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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
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Accession:GO:1990440 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.
Synonyms:exact_synonym: activation of transcription from RNA polymerase II promoter in response to ER stress;   stimulation of transcription from RNA polymerase II promoter in response to ER stress;   up-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;   upregulation of Pol II transcription induced by ER stress;   upregulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
 broad_synonym: ER stress-induced upregulation of transcription;   up-regulation of transcription induced by ER stress


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positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF3 activating transcription factor 3 IDA (PMID:24939851) ParkinsonsUK-UCL PMID:24939851 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G ATF4 activating transcription factor 4 IMP
IBA
IDA
(PMID:21113145)
(PMID:21873635)
(PMID:12871976)
ParkinsonsUK-UCL
GO_Central
PMID:12871976, PMID:21113145, PMID:21873635 NCBI chr22:39,514,494...39,522,686
Ensembl chr22:39,519,672...39,522,683
Ensembl chr22:39,519,672...39,522,683
JBrowse link
G ATF6 activating transcription factor 6 IDA
TAS
(PMID:11163209), (PMID:11256944), (PMID:16469704)
(PMID:22013210)
ParkinsonsUK-UCL PMID:11163209, PMID:11256944, PMID:16469704, PMID:22013210 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,320...161,964,070
JBrowse link
G ATF6B activating transcription factor 6 beta IDA
TAS
(PMID:11256944)
(PMID:22013210)
ParkinsonsUK-UCL PMID:11256944, PMID:22013210 NCBI chr 6:32,115,264...32,128,246
Ensembl chr 6:32,115,264...32,128,253
JBrowse link
G CEBPB CCAAT enhancer binding protein beta IDA (PMID:15775988) ParkinsonsUK-UCL PMID:15775988 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
JBrowse link
G CREB3L1 cAMP responsive element binding protein 3 like 1 ISS ParkinsonsUK-UCL GO_REF:0000024 NCBI chr11:46,277,661...46,321,409
Ensembl chr11:46,277,662...46,321,409
JBrowse link
G CREB3L3 cAMP responsive element binding protein 3 like 3 IDA (PMID:16469704) ParkinsonsUK-UCL PMID:16469704 NCBI chr19:4,153,631...4,173,054
Ensembl chr19:4,153,631...4,173,054
JBrowse link
G DDIT3 DNA damage inducible transcript 3 IMP
IBA
IDA
ISS
IGI
(PMID:22761832)
(PMID:21873635)
(PMID:15322075), (PMID:24939851)
(PMID:15775988)
ParkinsonsUK-UCL
GO_Central
PMID:15322075, PMID:15775988, PMID:21873635, PMID:22761832, PMID:24939851 GO_REF:0000024 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:MGI:3722921|PMID:14729979) ParkinsonsUK-UCL PMID:14729979 MGI:MGI:3722921 NCBI chr 2:88,556,741...88,627,464
Ensembl chr 2:88,556,741...88,627,464
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 TAS (PMID:14685163) ParkinsonsUK-UCL PMID:14685163 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 IGI
IBA
(PMID:11163209)
(PMID:21873635)
ParkinsonsUK-UCL
GO_Central
PMID:11163209, PMID:21873635 NCBI chr  X:21,839,617...21,885,423
Ensembl chr  X:21,839,617...21,885,423
JBrowse link
G TP53 tumor protein p53 ISS ParkinsonsUK-UCL GO_REF:0000024 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G XBP1 X-box binding protein 1 TAS (PMID:22013210) ParkinsonsUK-UCL PMID:22013210 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    response to stimulus 10153
      response to stress 4580
        cellular response to stress 2289
          response to endoplasmic reticulum stress 313
            positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 13
Path 2
Term Annotations click to browse term
  biological_process 18670
    metabolic process 12302
      cellular metabolic process 11281
        cellular aromatic compound metabolic process 6234
          nucleobase-containing compound metabolic process 5982
            nucleic acid metabolic process 5435
              RNA metabolic process 4899
                RNA biosynthetic process 3901
                  regulation of RNA biosynthetic process 3713
                    regulation of nucleic acid-templated transcription 3708
                      regulation of transcription, DNA-templated 3637
                        positive regulation of transcription, DNA-templated 1712
                          positive regulation of transcription by RNA polymerase II 1393
                            positive regulation of transcription from RNA polymerase II promoter in response to stress 27
                              positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.