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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
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Accession:GO:1990440 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.
Synonyms:exact_synonym: activation of transcription from RNA polymerase II promoter in response to ER stress;   stimulation of transcription from RNA polymerase II promoter in response to ER stress;   up-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;   upregulation of Pol II transcription induced by ER stress;   upregulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
 broad_synonym: ER stress-induced upregulation of transcription;   up-regulation of transcription induced by ER stress


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positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 ISO (PMID:24939851) ParkinsonsUK-UCL PMID:24939851 NCBI chrNW_004936557:909,302...922,619 JBrowse link
G Atf4 activating transcription factor 4 ISO (PMID:21113145)
(MGI:MGI:5433837|PMID:21113145), (MGI:MGI:5613480|PMID:12871976)
(PMID:12871976)
ParkinsonsUK-UCL PMID:12871976, PMID:21113145 MGI:MGI:5433837, MGI:MGI:5613480 NCBI chrNW_004936492:2,114,478...2,115,969 JBrowse link
G Atf6b activating transcription factor 6 beta ISO (PMID:11256944) ParkinsonsUK-UCL PMID:11256944 NCBI chrNW_004936727:1,476,061...1,487,353 JBrowse link
G Creb3l1 cAMP responsive element binding protein 3 like 1 ISO (MGI:MGI:5616321|PMID:15665855) ParkinsonsUK-UCL PMID:15665855 MGI:MGI:5616321, RGD:1558627 NCBI chrNW_004936562:2,739,908...2,772,484 JBrowse link
G Creb3l3 cAMP responsive element binding protein 3 like 3 ISO (MGI:MGI:5616319|PMID:16469704)
(PMID:16469704)
ParkinsonsUK-UCL PMID:16469704 MGI:MGI:5616319 NCBI chrNW_004936588:2,378,802...2,386,490 JBrowse link
G Ddit3 DNA damage inducible transcript 3 ISO (PMID:15322075), (PMID:24939851)
(PMID:15775988)
(MGI:MGI:3525819|PMID:15601821)
PMID:8657121
(PMID:22761832)
ParkinsonsUK-UCL PMID:8657121, PMID:15322075, PMID:15601821, PMID:15775988, PMID:22761832, PMID:24939851 MGI:MGI:3525819, RGD:1599740 NCBI chrNW_004936646:1,665,019...1,669,212 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:MGI:3722921|PMID:14729979) ParkinsonsUK-UCL PMID:14729979 MGI:MGI:3722921 NCBI chrNW_004936712:413,602...454,443 JBrowse link
G Mbtps2 membrane bound transcription factor peptidase, site 2 ISO (PMID:11163209) ParkinsonsUK-UCL PMID:11163209 NCBI chrNW_004936624:2,464,152...2,510,984 JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:5621265|PMID:16407291) ParkinsonsUK-UCL PMID:16407291 MGI:MGI:5621265 NCBI chrNW_004936595:919,807...935,367 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12001
    response to stimulus 6422
      response to stress 3058
        cellular response to stress 1653
          response to endoplasmic reticulum stress 223
            positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 9
Path 2
Term Annotations click to browse term
  biological_process 12001
    metabolic process 7670
      cellular metabolic process 7071
        cellular aromatic compound metabolic process 3755
          nucleobase-containing compound metabolic process 3585
            nucleic acid metabolic process 3298
              RNA metabolic process 2919
                RNA biosynthetic process 2373
                  regulation of RNA biosynthetic process 2292
                    regulation of nucleic acid-templated transcription 2287
                      regulation of transcription, DNA-templated 2279
                        positive regulation of transcription, DNA-templated 1388
                          positive regulation of transcription by RNA polymerase II 1112
                            positive regulation of transcription from RNA polymerase II promoter in response to stress 22
                              positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.