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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
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Accession:GO:1990441 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.
Synonyms:exact_synonym: ER stress-induced negative regulation of transcription from RNA polymerase II promoter;   down regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;   inhibition of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;   negative regulation of transcription from RNA polymerase II promoter in response to ER stress;   reduction of transcription from RNA polymerase II promoter under ER stress;   repression of transcription from RNA polymerase II promoter under ER stress;   suppression of transcription from RNA polymerase II promoter under ER stress


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negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO (PMID:21113145) RGD PMID:21113145 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Nck1 NCK adaptor protein 1 ISO (PMID:16835242)
UniProtKB:O55033 (MGI:MGI:5613475|PMID:16835242)
RGD PMID:16835242 MGI:MGI:5613475 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779
JBrowse link
G Nck2 NCK adaptor protein 2 ISO UniProtKB:Q99M51 (MGI:MGI:5613475|PMID:16835242) RGD PMID:16835242 MGI:MGI:5613475 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A ISO (MGI:MGI:5605960|PMID:11381086) RGD PMID:11381086 MGI:MGI:5605960 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 ISO (MGI:MGI:3840374|PMID:19328063) RGD PMID:19328063 MGI:MGI:3840374 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      response to stress 4061
        cellular response to stress 1982
          response to endoplasmic reticulum stress 261
            negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 5
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      cellular metabolic process 11085
        cellular aromatic compound metabolic process 5715
          nucleobase-containing compound metabolic process 5489
            nucleic acid metabolic process 4985
              RNA metabolic process 4469
                RNA biosynthetic process 3477
                  nucleic acid-templated transcription 3463
                    regulation of nucleic acid-templated transcription 3336
                      regulation of transcription, DNA-templated 3287
                        regulation of transcription by RNA polymerase II 2417
                          regulation of transcription from RNA polymerase II promoter in response to stress 51
                            negative regulation of transcription from RNA polymerase II promoter in response to stress 16
                              negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.