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Term:IRE1-TRAF2-ASK1 complex
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Accession:GO:1990604 term browser browse the term
Definition:A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K).
Synonyms:related_synonym: ERN1-TRAF2-ASK1 complex

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IRE1-TRAF2-ASK1 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1624291
G Ern2 endoplasmic reticulum to nucleus signaling 2 JBrowse link 1 192,126,023 192,142,865 RGD:1624291
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:1624291
G Traf2 Tnf receptor-associated factor 2 JBrowse link 3 2,746,061 2,770,690 RGD:1624291

Term paths to the root
Path 1
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  cellular_component 19843
    protein-containing complex 5779
      membrane protein complex 1210
        IRE1-TRAF2-ASK1 complex 4
Path 2
Term Annotations click to browse term
  cellular_component 19843
    cellular anatomical entity 19457
      organelle 12557
        membrane-bounded organelle 10879
          organelle membrane 2679
            endoplasmic reticulum membrane 860
              IRE1-TRAF2-ASK1 complex 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.