Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:HFE-transferrin receptor complex
go back to main search page
Accession:GO:1990712 term browser browse the term
Definition:A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription.


show annotations for term's descendants           Sort by:
 
HFE-transferrin receptor complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin ISO (PMID:9990067) BHF-UCL PMID:9990067 NCBI chr15:23,668,108...23,674,791
Ensembl chr15:41,836,345...41,842,991
JBrowse link
G HFE homeostatic iron regulator ISO (PMID:12704209), (PMID:22728873), (PMID:9465039), (PMID:9546397), (PMID:9990067)
(MGI:3695785|PMID:16893896)
BHF-UCL PMID:9465039, PMID:9546397, PMID:9990067, PMID:12704209, PMID:16893896, PMID:22728873 MGI:3695785 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591
JBrowse link
G HJV hemojuvelin BMP co-receptor ISO (PMID:22728873) BHF-UCL PMID:22728873 NCBI chr 1:121,738,465...121,742,743
Ensembl chr 1:113,926,383...113,930,761
JBrowse link
G LOC100995326 serotransferrin ISO (PMID:9546397) BHF-UCL PMID:9546397 NCBI chr 3:130,799,063...130,830,227
Ensembl chr 3:138,274,159...138,305,476
JBrowse link
G TFR2 transferrin receptor 2 ISO (PMID:12704209), (PMID:22728873)
(MGI:3695785|PMID:16893896)
BHF-UCL PMID:12704209, PMID:16893896, PMID:22728873 MGI:3695785 NCBI chr 7:92,647,431...92,669,889
Ensembl chr 7:106,048,935...106,069,238
JBrowse link
G TFRC transferrin receptor ISO (PMID:9465039), (PMID:9546397), (PMID:9990067)
(MGI:3695785|PMID:16893896)
BHF-UCL PMID:9465039, PMID:9546397, PMID:9990067, PMID:16893896 MGI:3695785 NCBI chr 3:193,384,817...193,417,532
Ensembl chr 3:203,333,953...203,373,998
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12671
    protein-containing complex 3939
      receptor complex 299
        plasma membrane signaling receptor complex 157
          HFE-transferrin receptor complex 6
Path 2
Term Annotations click to browse term
  cellular_component 12671
    cellular anatomical entity 12512
      cell periphery 3460
        plasma membrane 3329
          plasma membrane protein complex 413
            plasma membrane signaling receptor complex 157
              HFE-transferrin receptor complex 6
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.