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ONTOLOGY REPORT - ANNOTATIONS


Term:survivin complex
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Accession:GO:1990713 term browser browse the term
Definition:A protein complex that negatively regulates apoptotic processes. In human, this anti-apoptotic complex is a homodimer of BIRC5 (survivin) and provides one survivin molecule to the chromosomal passenger complex (CPC).
Comment:An example of this is BIRC5 in human (UniProt symbol O15392) in PMID:10949038 (inferred from physical interaction).
Synonyms:exact_synonym: Baculoviral IAP repeat-containing protein 5 complex
 narrow_synonym: survivin homodimer complex
 xref: IntAct:EBI-10714791;   IntAct:EBI-10727115


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  cellular_component 19738
    protein-containing complex 5748
      survivin complex 0
Path 2
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  cellular_component 19738
    cellular anatomical entity 19354
      organelle 12457
        intracellular organelle 11936
          intracellular membrane-bounded organelle 9924
            nucleus 6747
              nuclear lumen 3991
                nucleoplasm 3364
                  survivin complex 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.