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ONTOLOGY REPORT - ANNOTATIONS


Term:response to manganese-induced endoplasmic reticulum stress
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Accession:GO:1990737 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus.
Synonyms:exact_synonym: manganese-induced ER stress response;   response to Mn-induced ER stress;   response to manganese-induced ER stress


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response to manganese-induced endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr22:39,514,494...39,522,686
Ensembl chr22:39,519,672...39,522,683
Ensembl chr22:39,519,672...39,522,683
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 2:88,556,741...88,627,464
Ensembl chr 2:88,556,741...88,627,464
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,151...67,386,516
Ensembl chr14:67,360,151...67,386,516
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    response to stimulus 10152
      response to stress 4579
        cellular response to stress 2286
          response to endoplasmic reticulum stress 313
            response to manganese-induced endoplasmic reticulum stress 3
Path 2
Term Annotations click to browse term
  biological_process 18670
    cellular process 17687
      cellular response to stimulus 8419
        cellular response to chemical stimulus 3965
          cellular response to inorganic substance 338
            cellular response to metal ion 258
              cellular response to manganese ion 24
                response to manganese-induced endoplasmic reticulum stress 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.