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ONTOLOGY REPORT - ANNOTATIONS


Term:response to manganese-induced endoplasmic reticulum stress
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Accession:GO:1990737 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus.
Synonyms:exact_synonym: manganese-induced ER stress response;   response to Mn-induced ER stress;   response to manganese-induced ER stress


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response to manganese-induced endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chrNW_004936492:2,114,478...2,115,969 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chrNW_004936712:413,602...454,443 JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chrNW_004936495:10,746,687...10,769,304 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11998
    response to stimulus 6422
      response to stress 3059
        cellular response to stress 1652
          response to endoplasmic reticulum stress 223
            response to manganese-induced endoplasmic reticulum stress 3
Path 2
Term Annotations click to browse term
  biological_process 11998
    cellular process 11174
      cellular response to stimulus 5139
        cellular response to chemical stimulus 2708
          cellular response to inorganic substance 240
            cellular response to metal ion 203
              cellular response to manganese ion 22
                response to manganese-induced endoplasmic reticulum stress 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.