ONTOLOGY REPORT - ANNOTATIONS


Term:cellular detoxification
go back to main search page
Accession:GO:1990748 term browser browse the term
Definition:Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


show annotations for term's descendants       view all columns           Sort by:
 
cellular detoxification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:1624291
cellular detoxification of aldehyde term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1a1 aldo-keto reductase family 1 member A1 JBrowse link 5 135,482,068 135,498,693 RGD:1624291
RGD:13838799
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:1624291
G Rdh11 retinol dehydrogenase 11 JBrowse link 6 102,356,498 102,372,618 RGD:1600115
RGD:1624291
G Rdh12 retinol dehydrogenase 12 JBrowse link 6 102,392,828 102,405,750 RGD:1600115
RGD:1624291
cellular detoxification of nitrogen compound term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:1624291
G Gstm2 glutathione S-transferase mu 2 JBrowse link 2 210,778,041 210,782,807 RGD:1624291
G Gstm3 glutathione S-transferase mu 3 JBrowse link 2 210,685,204 210,688,273 RGD:1624291
G Gstm5 glutathione S-transferase, mu 5 JBrowse link 2 210,685,338 210,688,133 RGD:1624291
cellular oxidant detoxification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5ap arachidonate 5-lipoxygenase activating protein JBrowse link 12 6,854,930 6,879,112 RGD:1600115
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1600115
G Apom apolipoprotein M JBrowse link 20 5,120,473 5,123,073 RGD:1600115
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:1600115
G Clic2 chloride intracellular channel 2 JBrowse link 20 295,338 310,363 RGD:1600115
G Cygb cytoglobin JBrowse link 10 105,618,325 105,628,091 RGD:1600115
G Duox1 dual oxidase 1 JBrowse link 3 114,251,794 114,286,827 RGD:1600115
G Duox2 dual oxidase 2 JBrowse link 3 114,218,187 114,237,808 RGD:1600115
G Epx eosinophil peroxidase JBrowse link 10 75,160,690 75,171,774 RGD:1600115
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:1600115
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:1600115
G Gpx2 glutathione peroxidase 2 JBrowse link 6 99,839,960 99,843,245 RGD:1600115
G Gpx3 glutathione peroxidase 3 JBrowse link 10 40,247,436 40,255,423 RGD:1600115
G Gpx4 glutathione peroxidase 4 JBrowse link 7 12,516,357 12,519,154 RGD:1600115
G Gpx5 glutathione peroxidase 5 JBrowse link 17 45,508,657 45,518,686 RGD:1600115
G Gpx6 glutathione peroxidase 6 JBrowse link 17 45,439,268 45,446,952 RGD:1600115
G Gpx7 glutathione peroxidase 7 JBrowse link 5 128,001,766 128,009,610 RGD:1600115
G Gpx8 glutathione peroxidase 8 JBrowse link 2 44,903,337 44,907,046 RGD:1600115
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:1600115
G Gstk1 glutathione S-transferase kappa 1 JBrowse link 4 71,621,777 71,626,096 RGD:1600115
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:1600115
G Gsto2 glutathione S-transferase omega 2 JBrowse link 1 267,617,517 267,640,455 RGD:1600115
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:1600115
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:1600115
G Gstt2 glutathione S-transferase, theta 2 JBrowse link 20 13,760,810 13,764,481 RGD:1600115
G Hba-a1 hemoglobin alpha, adult chain 1 JBrowse link 10 15,602,794 15,603,649 RGD:1600115
G Hba-a2 hemoglobin alpha, adult chain 2 JBrowse link 10 15,589,364 15,590,207 RGD:1600115
G Hba-a3 hemoglobin alpha, adult chain 3 JBrowse link 10 15,577,249 15,577,977 RGD:1600115
G Hbb hemoglobin subunit beta JBrowse link 1 168,971,269 168,972,680 RGD:1600115
G Hbe1 hemoglobin subunit epsilon 1 JBrowse link 1 169,003,904 169,005,184 RGD:1600115
G Hbe2 hemoglobin, epsilon 2 JBrowse link 1 169,000,133 169,001,761 RGD:1600115
G Hbg1 hemoglobin subunit gamma 1 JBrowse link 1 168,992,841 168,994,219 RGD:1600115
G Hbz hemoglobin subunit zeta JBrowse link 10 15,609,348 15,610,826 RGD:1600115
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:1600115
G Iyd iodotyrosine deiodinase JBrowse link 1 40,086,513 40,100,966 RGD:1600115
G Kdm3b lysine demethylase 3B JBrowse link 18 27,593,823 27,631,129 RGD:1600115
G LOC100134871 beta globin minor gene JBrowse link 1 168,957,460 168,958,836 RGD:1600115
G LOC103690044 glutathione S-transferase omega-2 JBrowse link 1 271,228,018 271,243,517 RGD:1600115
G LOC103694857 hemoglobin subunit beta-2 RGD:1600115
G LOC689064 beta-globin JBrowse link 1 168,964,202 168,965,568 RGD:1600115
G Loxhd1 lipoxygenase homology domains 1 JBrowse link 18 73,645,365 73,812,271 RGD:1600115
G Lpo lactoperoxidase JBrowse link 10 75,100,385 75,120,247 RGD:1600115
G Ltc4s leukotriene C4 synthase JBrowse link 10 35,736,486 35,743,088 RGD:1600115
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link 4 172,119,382 172,134,609 RGD:1600115
G Mgst2 microsomal glutathione S-transferase 2 JBrowse link 2 140,708,396 140,727,381 RGD:1600115
G Mgst3 microsomal glutathione S-transferase 3 JBrowse link 13 85,601,499 85,622,392 RGD:1600115
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:1600115
G Nnt nicotinamide nucleotide transhydrogenase JBrowse link 2 52,189,523 52,283,095 RGD:13513982
G Nxn nucleoredoxin JBrowse link 10 64,411,710 64,550,147 RGD:1600115
G Prdx3 peroxiredoxin 3 JBrowse link 1 282,238,774 282,251,193 RGD:1600115
G Prdx4 peroxiredoxin 4 JBrowse link X 43,495,453 43,512,994 RGD:1600115
G Prdx5 peroxiredoxin 5 JBrowse link 1 222,164,462 222,167,447 RGD:1600115
G Prdx6 peroxiredoxin 6 JBrowse link 13 79,077,567 79,088,113 RGD:1624291
RGD:1600115
G Prxl2a peroxiredoxin like 2A JBrowse link 16 17,494,000 17,513,781 RGD:1600115
G Prxl2b peroxiredoxin like 2B JBrowse link 5 172,304,799 172,307,402 RGD:1600115
G Prxl2c peroxiredoxin like 2C JBrowse link 17 1,798,224 1,830,011 RGD:1600115
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:1600115
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1600115
G Pxdn peroxidasin JBrowse link 6 48,866,496 48,982,368 RGD:1600115
G S100a8 S100 calcium binding protein A8 JBrowse link 2 190,073,239 190,074,333 RGD:1600115
G S100a9 S100 calcium binding protein A9 JBrowse link 2 190,097,436 190,100,209 RGD:1600115
G Selenof selenoprotein F JBrowse link 2 250,600,823 250,633,903 RGD:1600115
G Selenos selenoprotein S JBrowse link 1 126,979,579 126,989,344 RGD:1600115
G Selenot selenoprotein T JBrowse link 2 148,765,412 148,781,080 RGD:12793008
G Selenow selenoprotein W JBrowse link 1 77,530,692 77,535,765 RGD:1600115
G Sesn1 sestrin 1 JBrowse link 20 46,667,116 46,758,306 RGD:1624291
RGD:1600115
G Sesn2 sestrin 2 JBrowse link 5 150,684,891 150,703,846 RGD:1624291
RGD:1600115
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 JBrowse link 5 24,402,895 24,419,651 RGD:1600115
G Tpo thyroid peroxidase JBrowse link 6 49,020,918 49,089,855 RGD:1600115
G Txn1 thioredoxin 1 JBrowse link 5 75,049,735 75,057,731 RGD:1600115
G Txndc17 thioredoxin domain containing 17 JBrowse link 10 58,776,792 58,779,764 RGD:1600115
G Txnrd1 thioredoxin reductase 1 JBrowse link 7 26,946,124 26,984,400 RGD:1600115
G Txnrd2 thioredoxin reductase 2 JBrowse link 11 86,667,994 86,716,063 RGD:1600115
G Txnrd3 thioredoxin reductase 3 JBrowse link 4 121,612,332 121,650,543 RGD:1600115
G Ubiad1 UbiA prenyltransferase domain containing 1 JBrowse link 5 165,247,630 165,259,228 RGD:1600115
formaldehyde catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide JBrowse link 2 243,702,035 243,720,063 RGD:13792537
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide JBrowse link 2 243,728,500 243,740,907 RGD:1624291
RGD:13792537
G Esd esterase D JBrowse link 15 56,756,848 56,776,348 RGD:1600115
positive regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:9590277
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
regulation of removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:1624291
RGD:1600115
G Fbln5 fibulin 5 JBrowse link 6 125,644,797 125,723,957 RGD:1624291
RGD:1600115
G Gch1 GTP cyclohydrolase 1 JBrowse link 15 23,935,011 23,968,971 RGD:1624291
RGD:1600115
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:1624291
RGD:1600115
regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Szt2 SZT2 subunit of KICSTOR complex JBrowse link 5 137,192,120 137,238,384 RGD:1624291
RGD:8554220
removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa4 apolipoprotein A4 JBrowse link 8 50,536,983 50,539,371 RGD:1624291
RGD:1600115
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:1624291
G Ccs copper chaperone for superoxide dismutase JBrowse link 1 220,075,251 220,096,319 RGD:1600115
RGD:13792537
G Fancc FA complementation group C JBrowse link 17 826,512 955,703 RGD:1624291
RGD:1600115
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:1624291
RGD:1600115
G Mt3 metallothionein 3 JBrowse link 19 11,324,708 11,326,112 RGD:1624291
RGD:1600115
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:1624291
RGD:1600115
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:1600115
G Prdx1 peroxiredoxin 1 JBrowse link 5 135,536,413 135,551,986 RGD:1624291
RGD:13792537
G Prdx2 peroxiredoxin 2 JBrowse link 19 26,084,816 26,090,095 RGD:1624291
RGD:13792537
RGD:1600115
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:730094
RGD:13792537
RGD:1624291
RGD:1600115
RGD:8655968
RGD:1601266
RGD:634854
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:2291939
RGD:1624291
RGD:2291946
RGD:2317387
G Sod3 superoxide dismutase 3 JBrowse link 14 60,958,583 60,971,143 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17896
    detoxification 119
      cellular detoxification 108
        cellular detoxification of aldehyde + 7
        cellular detoxification of cadmium ion 0
        cellular detoxification of copper ion 0
        cellular detoxification of fluoride 0
        cellular detoxification of nitrogen compound 4
        cellular oxidant detoxification + 96
        toxic metabolite repair 0
Path 2
Term Annotations click to browse term
  biological_process 17896
    cellular process 16040
      cellular response to stimulus 8288
        cellular response to chemical stimulus 3279
          cellular response to toxic substance 304
            cellular detoxification 108
              cellular detoxification of aldehyde + 7
              cellular detoxification of cadmium ion 0
              cellular detoxification of copper ion 0
              cellular detoxification of fluoride 0
              cellular detoxification of nitrogen compound 4
              cellular oxidant detoxification + 96
              toxic metabolite repair 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.