ONTOLOGY REPORT - ANNOTATIONS


Term:adaptive thermogenesis
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Accession:GO:1990845 term browser browse the term
Definition:The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.


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adaptive thermogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HNRNPU heterogeneous nuclear ribonucleoprotein U JBrowse link 1 225,830,663 225,842,031 RGD:9068941
G PM20D1 peptidase M20 domain containing 1 JBrowse link 1 185,720,642 185,742,757 RGD:9068941
G PPARGC1A PPARG coactivator 1 alpha JBrowse link 4 23,483,377 24,160,574 RGD:9068941
G THADA THADA armadillo repeat containing JBrowse link 2A 44,166,091 44,529,671 RGD:9068941
G UCP1 uncoupling protein 1 JBrowse link 4 144,230,858 144,239,803 RGD:9068941
G UCP2 uncoupling protein 2 JBrowse link 11 72,354,529 72,363,185 RGD:9068941
G UCP3 uncoupling protein 3 JBrowse link 11 72,380,180 72,389,274 RGD:9068941
G ZBTB7B zinc finger and BTB domain containing 7B JBrowse link 1 133,959,365 133,975,729 RGD:9068941
diet induced thermogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRB1 adrenoceptor beta 1 JBrowse link 10 114,075,628 114,076,596 RGD:9068941
G ADRB2 adrenoceptor beta 2 JBrowse link 5 150,267,321 150,269,339 RGD:9068941
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 JBrowse link 12 106,150,955 106,214,038 RGD:9068941
G BMP8A bone morphogenetic protein 8a JBrowse link 1 40,122,134 40,138,165 RGD:9068941
G MC4R melanocortin 4 receptor JBrowse link 18 57,069,089 57,070,670 RGD:9068941
G OMA1 OMA1 zinc metallopeptidase JBrowse link 1 59,253,869 59,516,474 RGD:9068941
G TRPV1 transient receptor potential cation channel subfamily V member 1 JBrowse link 17 3,609,952 3,655,011 RGD:9068941
G TRPV4 transient receptor potential cation channel subfamily V member 4 JBrowse link 12 110,754,238 110,786,182 RGD:9068941
G UCP1 uncoupling protein 1 JBrowse link 4 144,230,858 144,239,803 RGD:9068941
negative regulation of cold-induced thermogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABHD6 abhydrolase domain containing 6 JBrowse link 3 59,586,537 59,641,824 RGD:9068941
G ACOT11 acyl-CoA thioesterase 11 JBrowse link 1 55,411,806 55,501,119 RGD:9068941
G ACOT13 acyl-CoA thioesterase 13 JBrowse link 6 24,837,145 24,872,121 RGD:9068941
G ACTN3 actinin alpha 3 JBrowse link 11 65,229,043 65,245,429 RGD:9068941
G ACVR2B activin A receptor type 2B JBrowse link 3 38,633,097 38,671,843 RGD:9068941
G ADAM17 ADAM metallopeptidase domain 17 JBrowse link 2A 9,641,194 9,708,091 RGD:9068941
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 JBrowse link 21 26,738,671 26,788,736 RGD:9068941
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 3 192,341,471 192,354,885 RGD:9068941
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 JBrowse link 9 71,680,352 71,859,144 RGD:9068941
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 11 13,163,028 13,240,376 RGD:9068941
G ARRDC3 arrestin domain containing 3 JBrowse link 5 24,126,407 24,140,858 RGD:9068941
G ATF4 activating transcription factor 4 JBrowse link 22 38,246,337 38,249,333 RGD:9068941
G CIDEA cell death inducing DFFA like effector a JBrowse link 18 17,162,126 17,185,450 RGD:9068941
G DDIT3 DNA damage inducible transcript 3 JBrowse link 12 31,664,766 31,668,699 RGD:9068941
G DOCK7 dedicator of cytokinesis 7 JBrowse link 1 63,528,826 63,760,513 RGD:9068941
G FLCN folliculin JBrowse link 17 38,988,520 39,013,189 RGD:9068941
G FOXC2 forkhead box C2 JBrowse link 16 86,569,509 86,571,878 RGD:9068941
G HOXC10 homeobox C10 JBrowse link 12 35,553,262 35,558,393 RGD:9068941
G ID1 inhibitor of DNA binding 1, HLH protein JBrowse link 20 28,535,470 28,536,726 RGD:9068941
G IL15 interleukin 15 JBrowse link 4 145,307,339 145,416,622 RGD:9068941
G IL18R1 interleukin 18 receptor 1 JBrowse link 2A 103,459,397 103,488,025 RGD:9068941
G IP6K1 inositol hexakisphosphate kinase 1 JBrowse link 3 50,892,279 50,954,149 RGD:9068941
G LAMA4 laminin subunit alpha 4 JBrowse link 6 113,995,888 114,141,276 RGD:9068941
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 JBrowse link 11 27,232,801 27,291,571 RGD:9068941
G LNPEP leucyl and cystinyl aminopeptidase JBrowse link 5 97,800,922 97,902,830 RGD:9068941
G MAP2K6 mitogen-activated protein kinase kinase 6 JBrowse link 17 68,730,011 68,870,713 RGD:9068941
G NOTCH1 notch receptor 1 JBrowse link 9 136,544,639 136,595,511 RGD:9068941
G NOVA1 NOVA alternative splicing regulator 1 JBrowse link 14 25,314,077 25,466,715 RGD:9068941
G NOVA2 NOVA alternative splicing regulator 2 JBrowse link 19 51,483,909 51,524,480 RGD:9068941
G NPR3 natriuretic peptide receptor 3 JBrowse link 5 82,921,035 83,004,964 RGD:9068941
G NR1D1 nuclear receptor subfamily 1 group D member 1 JBrowse link 17 17,409,669 17,417,600 RGD:9068941
G NR1H2 nuclear receptor subfamily 1 group H member 2 JBrowse link 19 56,243,124 56,250,024 RGD:9068941
G NR1H3 nuclear receptor subfamily 1 group H member 3 JBrowse link 11 47,748,452 47,768,672 RGD:9068941
G NRDC nardilysin convertase JBrowse link 1 52,535,563 52,625,998 RGD:9068941
G PCTP phosphatidylcholine transfer protein JBrowse link 17 54,696,803 54,770,248 RGD:9068941
G PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase JBrowse link 12 134,787,682 134,800,626 RGD:9068941
G PLCL1 phospholipase C like 1 (inactive) JBrowse link 2B 202,947,931 203,286,656 RGD:9068941
G PLCL2 phospholipase C like 2 JBrowse link 3 17,154,506 17,351,287 RGD:9068941
G RB1 RB transcriptional corepressor 1 JBrowse link 13 48,155,608 48,326,396 RGD:9068941
G RBPJ recombination signal binding protein for immunoglobulin kappa J region JBrowse link 4 25,996,223 26,107,683 RGD:9068941
G RHEB Ras homolog, mTORC1 binding JBrowse link 7 155,203,244 155,235,404 RGD:9068941
G STK11 serine/threonine kinase 11 JBrowse link 19 1,188,537 1,210,677 RGD:9068941
G TFE3 transcription factor binding to IGHM enhancer 3 JBrowse link X 49,182,795 49,197,194 RGD:9068941
G TLE3 TLE family member 3, transcriptional corepressor JBrowse link 15 67,768,456 67,817,589 RGD:9068941
G TLR4 toll like receptor 4 JBrowse link 9 117,180,250 117,193,510 RGD:9068941
G WNT10B Wnt family member 10B JBrowse link 12 40,659,106 40,665,734 RGD:9068941
G ZNF423 zinc finger protein 423 JBrowse link 16 48,635,379 48,969,776 RGD:9068941
positive regulation of cold-induced thermogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACADL acyl-CoA dehydrogenase long chain JBrowse link 2B 215,847,775 215,885,524 RGD:9068941
G ACHE acetylcholinesterase (Cartwright blood group) JBrowse link 7 106,311,944 106,318,190 RGD:9068941
G ACSL1 acyl-CoA synthetase long chain family member 1 JBrowse link 4 189,145,403 189,216,458 RGD:9068941
G ADCYAP1 adenylate cyclase activating polypeptide 1 JBrowse link 18 15,712,078 15,718,693 RGD:9068941
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 3 192,341,471 192,354,885 RGD:9068941
G ADIPOR1 adiponectin receptor 1 JBrowse link 1 182,837,589 182,854,749 RGD:9068941
G ADIPOR2 adiponectin receptor 2 JBrowse link 12 1,750,756 1,852,251 RGD:9068941
G ADRB1 adrenoceptor beta 1 JBrowse link 10 114,075,628 114,076,596 RGD:9068941
G ADRB2 adrenoceptor beta 2 JBrowse link 5 150,267,321 150,269,339 RGD:9068941
G ADRB3 adrenoceptor beta 3 JBrowse link 8 34,440,099 34,444,043 RGD:9068941
G ALMS1 ALMS1 centrosome and basal body associated protein JBrowse link 2A 74,926,650 75,158,734 RGD:9068941
G APC APC regulator of WNT signaling pathway JBrowse link 5 113,873,993 114,009,709 RGD:9068941
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 JBrowse link 12 106,150,955 106,214,038 RGD:9068941
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin JBrowse link 11 61,399,314 61,416,494 RGD:9068941
G CAV1 caveolin 1 JBrowse link 7 121,193,678 121,229,655 RGD:9068941
G CCR2 C-C motif chemokine receptor 2 JBrowse link 3 47,361,118 47,368,312 RGD:9068941
G CD36 CD36 molecule JBrowse link 7 86,228,856 86,305,865 RGD:9068941
G CMKLR1 chemerin chemokine-like receptor 1 JBrowse link 12 109,256,329 109,307,526 RGD:9068941
G CNOT3 CCR4-NOT transcription complex subunit 3 JBrowse link 19 59,913,040 59,931,108 RGD:9068941
G CPT2 carnitine palmitoyltransferase 2 JBrowse link 1 54,069,334 54,086,994 RGD:9068941
G CXCR4 C-X-C motif chemokine receptor 4 JBrowse link 2B 140,185,803 140,189,626 RGD:9068941
G DBH dopamine beta-hydroxylase JBrowse link 9 133,371,818 133,394,581 RGD:9068941
G DECR1 2,4-dienoyl-CoA reductase 1 JBrowse link 8 88,642,676 88,693,224 RGD:9068941
G DIO2 iodothyronine deiodinase 2 JBrowse link 14 79,956,305 79,970,938 RGD:9068941
G DYNC1H1 dynein cytoplasmic 1 heavy chain 1 JBrowse link 14 102,406,807 102,489,678 RGD:9068941
G EHMT1 euchromatic histone lysine methyltransferase 1 JBrowse link 9 137,699,213 137,895,564 RGD:9068941
G ELOVL3 ELOVL fatty acid elongase 3 JBrowse link 10 102,297,291 102,300,601 RGD:9068941
G ELOVL6 ELOVL fatty acid elongase 6 JBrowse link 4 113,112,941 113,260,883 RGD:9068941
G EPAS1 endothelial PAS domain protein 1 JBrowse link 2A 47,332,286 47,421,560 RGD:9068941
G ESRRG estrogen related receptor gamma JBrowse link 1 196,929,197 197,508,064 RGD:9068941
G FABP4 fatty acid binding protein 4 JBrowse link 8 79,624,899 79,629,442 RGD:9068941
G FABP5 fatty acid binding protein 5 JBrowse link 8 79,426,678 79,430,879 RGD:9068941
G FFAR4 free fatty acid receptor 4 JBrowse link 10 93,823,004 93,846,402 RGD:9068941
G FGF21 fibroblast growth factor 21 JBrowse link 19 54,345,966 54,347,712 RGD:9068941
G FH fumarate hydratase JBrowse link 1 222,041,142 222,063,271 RGD:9068941
G G0S2 G0/G1 switch 2 JBrowse link 1 190,056,941 190,058,086 RGD:9068941
G GADD45G growth arrest and DNA damage inducible gamma JBrowse link 9 88,740,411 88,741,965 RGD:9068941
G GATM glycine amidinotransferase JBrowse link 15 42,639,597 42,657,209 RGD:9068941
G GHRL ghrelin and obestatin prepropeptide JBrowse link 3 10,573,537 10,580,723 RGD:9068941
G GJA1 gap junction protein alpha 1 JBrowse link 6 123,348,744 123,360,887 RGD:9068941
G GNAS GNAS complex locus JBrowse link 20 56,460,906 56,620,313 RGD:9068941
G GPR3 G protein-coupled receptor 3 JBrowse link 1 27,702,003 27,705,195 RGD:9068941
G GRB10 growth factor receptor bound protein 10 JBrowse link 7 51,474,166 51,676,864 RGD:9068941
G HADH hydroxyacyl-CoA dehydrogenase JBrowse link 4 111,067,537 111,112,945 RGD:9068941
G HCRT hypocretin neuropeptide precursor JBrowse link 17 15,353,203 15,354,594 RGD:9068941
G HDAC3 histone deacetylase 3 JBrowse link 5 143,094,406 143,110,322 RGD:9068941
G HSF1 heat shock transcription factor 1 JBrowse link 8 144,062,137 144,067,725 RGD:9068941
G IGF1R insulin like growth factor 1 receptor JBrowse link 15 96,576,930 96,832,974 RGD:9068941
G IL13 interleukin 13 JBrowse link 5 134,235,788 134,240,548 RGD:9068941
G IL18 interleukin 18 JBrowse link 11 110,867,586 110,888,371 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G IL4R interleukin 4 receptor JBrowse link 16 27,686,760 27,737,445 RGD:9068941
G IRF4 interferon regulatory factor 4 JBrowse link 6 341,637 360,492 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 9 5,006,271 5,156,626 RGD:9068941
G KDM1A lysine demethylase 1A JBrowse link 1 23,153,066 23,217,693 RGD:9068941
G KDM3A lysine demethylase 3A JBrowse link 2A 88,043,712 88,094,244 RGD:9068941
G KDM6B lysine demethylase 6B JBrowse link 17 7,858,734 7,876,220 RGD:9068941
G KSR2 kinase suppressor of ras 2 JBrowse link 12 118,416,905 118,926,529 RGD:9068941
G LCN2 lipocalin 2 JBrowse link 9 127,940,799 127,944,798 RGD:9068941
G LEP leptin JBrowse link 7 132,884,994 132,901,519 RGD:9068941
G LEPR leptin receptor JBrowse link 1 66,651,994 66,764,768 RGD:9068941
G LPIN1 lipin 1 JBrowse link 2A 11,847,419 11,961,551 RGD:9068941
G MFN2 mitofusin 2 JBrowse link 1 11,945,849 11,981,077 RGD:9068941
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 70,852,687 70,894,921 RGD:9068941
G OMA1 OMA1 zinc metallopeptidase JBrowse link 1 59,253,869 59,516,474 RGD:9068941
G OXTR oxytocin receptor JBrowse link 3 8,946,493 8,961,823 RGD:9068941
G PDGFC platelet derived growth factor C JBrowse link 4 160,921,353 161,132,308 RGD:9068941
G PEMT phosphatidylethanolamine N-methyltransferase JBrowse link 17 38,651,026 38,737,202 RGD:9068941
G PER2 period circadian regulator 2 JBrowse link 2B 244,328,122 244,371,040 RGD:9068941
G PHOX2B paired like homeobox 2B JBrowse link 4 41,918,047 41,922,449 RGD:9068941
G PLAC8 placenta associated 8 JBrowse link 4 46,939,019 46,964,131 RGD:9068941
G PPARGC1A PPARG coactivator 1 alpha JBrowse link 4 23,483,377 24,160,574 RGD:9068941
G PPARGC1B PPARG coactivator 1 beta JBrowse link 5 151,172,020 151,286,285 RGD:9068941
G PRDM16 PR/SET domain 16 JBrowse link 1 2,981,854 3,231,741 RGD:9068941
G PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 JBrowse link 12 120,624,004 120,637,585 RGD:9068941
G PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2 JBrowse link 1 112,934,877 112,952,364 RGD:9068941
G PRLR prolactin receptor JBrowse link 5 80,420,061 80,585,559 RGD:9068941
G PTH2R parathyroid hormone 2 receptor JBrowse link 2B 213,722,389 213,866,526 RGD:9068941
G SCD stearoyl-CoA desaturase JBrowse link 10 100,428,627 100,446,647 RGD:9068941
G SIRT6 sirtuin 6 JBrowse link 19 4,146,057 4,154,132 RGD:9068941
G SLN sarcolipin JBrowse link 11 106,076,861 106,081,534 RGD:9068941
G STAT6 signal transducer and activator of transcription 6 JBrowse link 12 32,068,645 32,085,099 RGD:9068941
G SYK spleen associated tyrosine kinase JBrowse link 9 89,959,599 90,056,101 RGD:9068941
G THRA thyroid hormone receptor alpha JBrowse link 17 17,420,186 17,448,502 RGD:9068941
G TRPM8 transient receptor potential cation channel subfamily M member 8 JBrowse link 2B 240,029,984 240,130,524 RGD:9068941
G TRPV2 transient receptor potential cation channel subfamily V member 2 JBrowse link 2A 110,620,793 110,642,926 RGD:9068941
G TSHR thyroid stimulating hormone receptor JBrowse link 14 80,718,183 80,907,839 RGD:9068941
G UCP1 uncoupling protein 1 JBrowse link 4 144,230,858 144,239,803 RGD:9068941
G UCP2 uncoupling protein 2 JBrowse link 11 72,354,529 72,363,185 RGD:9068941
G VEGFA vascular endothelial growth factor A JBrowse link 6 44,651,855 44,666,353 RGD:9068941
G YBX2 Y-box binding protein 2 JBrowse link 17 7,306,548 7,312,632 RGD:9068941
G ZBTB7B zinc finger and BTB domain containing 7B JBrowse link 1 133,959,365 133,975,729 RGD:9068941
G ZNF516 zinc finger protein 516 JBrowse link 18 73,021,762 73,150,904 RGD:9068941

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  biological_process 15676
    metabolic process 10496
      adaptive thermogenesis 147
        cold-induced thermogenesis + 139
        diet induced thermogenesis 9
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.