ONTOLOGY REPORT - ANNOTATIONS


Term:adaptive thermogenesis
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Accession:GO:1990845 term browser browse the term
Definition:The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.


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adaptive thermogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HNRNPU heterogeneous nuclear ribonucleoprotein U JBrowse link 7 35,832,956 35,842,898 RGD:9068941
G PM20D1 peptidase M20 domain containing 1 JBrowse link 38 2,247,645 2,270,286 RGD:13508589
RGD:9068941
G PPARGC1A PPARG coactivator 1 alpha JBrowse link 3 85,645,942 86,284,570 RGD:9068941
G THADA THADA armadillo repeat containing JBrowse link 10 45,754,873 46,084,496 RGD:9068941
G UCP1 uncoupling protein 1 JBrowse link 19 2,254,881 2,289,902 RGD:13508589
RGD:9068941
G UCP2 uncoupling protein 2 JBrowse link 21 24,304,410 24,311,392 RGD:9068941
G ZBTB7B zinc finger and BTB domain containing 7B JBrowse link 7 42,468,376 42,482,219 RGD:9068941
diet induced thermogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRB1 adrenoceptor beta 1 JBrowse link 28 24,908,224 24,909,684 RGD:9068941
G ADRB2 adrenoceptor beta 2 JBrowse link 4 60,048,502 60,050,447 RGD:9068941
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 JBrowse link 10 33,192,261 33,243,034 RGD:13508589
RGD:9068941
G MC4R melanocortin 4 receptor JBrowse link 1 16,131,829 16,132,827 RGD:9068941
G OMA1 OMA1 zinc metallopeptidase JBrowse link 5 51,143,437 51,213,913 RGD:13508589
RGD:9068941
G SCTR secretin receptor JBrowse link 19 30,505,059 30,577,371 RGD:9068941
G TRPV1 transient receptor potential cation channel subfamily V member 1 JBrowse link 9 47,404,987 47,443,871 RGD:13508589
RGD:9068941
G TRPV4 transient receptor potential cation channel subfamily V member 4 JBrowse link 26 17,293,334 17,330,156 RGD:9068941
G UCP1 uncoupling protein 1 JBrowse link 19 2,254,881 2,289,902 RGD:9068941
negative regulation of cold-induced thermogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABHD6 abhydrolase domain containing 6 JBrowse link 20 32,301,120 32,331,030 RGD:13508589
RGD:9068941
G ACOT11 acyl-CoA thioesterase 11 JBrowse link 5 54,510,865 54,558,740 RGD:9068941
G ACOT13 acyl-CoA thioesterase 13 JBrowse link 35 22,707,214 22,723,345 RGD:13508589
RGD:9068941
G ACTN3 actinin alpha 3 JBrowse link 18 50,787,353 50,801,036 RGD:9068941
G ACVR2B activin A receptor type 2B JBrowse link 23 8,211,555 8,225,596 RGD:9068941
G ADAM17 ADAM metallopeptidase domain 17 JBrowse link 17 6,589,874 6,638,788 RGD:9068941
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 JBrowse link 31 22,242,901 22,289,453 RGD:9068941
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 34 19,398,310 19,410,519 RGD:13508589
RGD:9068941
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 JBrowse link 1 84,940,411 84,994,789 RGD:9068941
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 21 36,254,235 36,323,915 RGD:9068941
G ARRDC3 arrestin domain containing 3 JBrowse link 3 17,691,631 17,705,507 RGD:13508589
RGD:9068941
G ATF4 activating transcription factor 4 JBrowse link 10 25,528,880 25,531,018 RGD:13508589
RGD:9068941
G CIDEA cell death inducing DFFA like effector a JBrowse link 7 77,685,383 77,703,320 RGD:13508589
RGD:9068941
G DDIT3 DNA damage inducible transcript 3 JBrowse link 10 1,606,693 1,612,410 RGD:13508589
RGD:9068941
G DOCK7 dedicator of cytokinesis 7 JBrowse link 5 47,435,209 47,653,312 RGD:9068941
G FLCN folliculin JBrowse link 5 42,176,093 42,195,718 RGD:13508589
RGD:9068941
G FOXC2 forkhead box C2 JBrowse link 5 66,234,336 66,296,007 RGD:9068941
RGD:13508589
G HOXC10 homeobox C10 JBrowse link 27 1,272,272 1,277,411 RGD:13508589
RGD:9068941
G ID1 inhibitor of DNA binding 1, HLH protein JBrowse link 24 21,094,339 21,096,276 RGD:9068941
G IL15 interleukin 15 JBrowse link 19 1,339,607 1,364,762 RGD:13508589
RGD:9068941
G IL18R1 interleukin 18 receptor 1 JBrowse link 10 40,614,336 40,653,300 RGD:13508589
RGD:9068941
G IP6K1 inositol hexakisphosphate kinase 1 JBrowse link 20 39,484,487 39,550,199 RGD:9068941
G LAMA4 laminin subunit alpha 4 JBrowse link 12 68,535,614 68,639,115 RGD:9068941
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 JBrowse link 21 47,952,019 47,995,530 RGD:9068941
G LNPEP leucyl and cystinyl aminopeptidase JBrowse link 3 12,668,994 12,766,712 RGD:13508589
RGD:9068941
G MAP2K6 mitogen-activated protein kinase kinase 6 JBrowse link 9 15,840,714 15,962,400 RGD:13508589
RGD:9068941
G NOTCH1 notch receptor 1 JBrowse link 9 48,975,972 49,018,985 RGD:9068941
G NOVA1 NOVA alternative splicing regulator 1 JBrowse link 8 6,133,608 6,281,508 RGD:13508589
RGD:9068941
G NOVA2 NOVA alternative splicing regulator 2 JBrowse link 1 109,657,693 109,683,277 RGD:9068941
G NPR3 natriuretic peptide receptor 3 JBrowse link 4 74,794,553 74,863,344 RGD:9068941
G NR1D1 nuclear receptor subfamily 1 group D member 1 JBrowse link 9 22,461,556 22,469,243 RGD:13508589
RGD:9068941
G NR1H2 nuclear receptor subfamily 1 group H member 2 JBrowse link 1 106,332,691 106,339,168 RGD:9068941
G NR1H3 nuclear receptor subfamily 1 group H member 3 JBrowse link 18 42,333,173 42,346,152 RGD:9068941
G NRDC nardilysin convertase JBrowse link 15 9,413,878 9,505,355 RGD:9068941
G PCTP phosphatidylcholine transfer protein JBrowse link 9 30,725,209 30,749,891 RGD:9068941
G PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase JBrowse link 26 406,871 414,874 RGD:9068941
G PLCL1 phospholipase C like 1 (inactive) JBrowse link 37 7,235,403 7,575,429 RGD:13508589
RGD:9068941
G PLCL2 phospholipase C like 2 JBrowse link 23 25,814,392 25,999,666 RGD:9068941
G RB1 RB transcriptional corepressor 1 JBrowse link 22 3,061,621 3,204,625 RGD:9068941
G RBPJ recombination signal binding protein for immunoglobulin kappa J region JBrowse link 3 84,060,417 84,286,008 RGD:13508589
RGD:9068941
G RHEB Ras homolog, mTORC1 binding JBrowse link 16 15,439,910 15,483,489 RGD:13508589
RGD:9068941
G STK11 serine/threonine kinase 11 JBrowse link 20 57,558,966 57,579,163 RGD:9068941
G TFE3 transcription factor binding to IGHM enhancer 3 JBrowse link X 42,181,639 42,192,709 RGD:9068941
G TLE3 TLE family member 3, transcriptional corepressor JBrowse link 30 33,803,719 33,895,204 RGD:9068941
G TLR4 toll like receptor 4 JBrowse link 11 71,356,390 71,367,166 RGD:13508589
RGD:9068941
G ZNF423 zinc finger protein 423 JBrowse link 2 65,512,342 65,778,410 RGD:9068941
positive regulation of cold-induced thermogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACADL acyl-CoA dehydrogenase long chain JBrowse link 37 18,028,244 18,073,975 RGD:9068941
G ACHE acetylcholinesterase JBrowse link 6 8,874,747 8,879,926 RGD:9068941
G ACSL1 acyl-CoA synthetase long chain family member 1 JBrowse link 16 45,735,675 45,806,235 RGD:9068941
G ADCYAP1 adenylate cyclase activating polypeptide 1 JBrowse link 7 67,682,421 67,691,035 RGD:9068941
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 34 19,398,310 19,410,519 RGD:13508589
RGD:9068941
G ADIPOR1 adiponectin receptor 1 JBrowse link 7 240,035 254,287 RGD:13508589
RGD:9068941
G ADIPOR2 adiponectin receptor 2 JBrowse link 27 43,739,269 43,840,116 RGD:13508589
RGD:9068941
G ADRB1 adrenoceptor beta 1 JBrowse link 28 24,908,224 24,909,684 RGD:9068941
G ADRB2 adrenoceptor beta 2 JBrowse link 4 60,048,502 60,050,447 RGD:9068941
G ADRB3 adrenoceptor beta 3 JBrowse link 16 27,445,601 27,446,796 RGD:9068941
G ALMS1 ALMS1 centrosome and basal body associated protein JBrowse link 17 49,301,397 49,513,729 RGD:9068941
G APC APC regulator of WNT signaling pathway JBrowse link 3 252,052 380,506 RGD:9068941
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 JBrowse link 10 33,192,261 33,243,034 RGD:13508589
RGD:9068941
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin JBrowse link 18 53,958,380 53,971,120 RGD:9068941
G CAV1 caveolin 1 JBrowse link 14 55,458,934 55,494,563 RGD:13508589
RGD:9068941
G CCR2 C-C motif chemokine receptor 2 JBrowse link 20 42,305,344 42,313,258 RGD:13508589
RGD:9068941
G CD36 CD36 molecule JBrowse link 18 20,299,808 20,375,856 RGD:13508589
RGD:9068941
G CEBPB CCAAT enhancer binding protein beta JBrowse link 24 36,661,294 36,663,162 RGD:9068941
G CMKLR1 chemerin chemokine-like receptor 1 JBrowse link 26 18,487,700 18,539,678 RGD:13508589
RGD:9068941
G CNOT3 CCR4-NOT transcription complex subunit 3 JBrowse link 1 103,057,392 103,070,612 RGD:13508589
RGD:9068941
G CPT2 carnitine palmitoyltransferase 2 JBrowse link 5 55,718,209 55,786,175 RGD:9068941
G CXCR4 C-X-C motif chemokine receptor 4 JBrowse link 19 38,874,650 38,877,740 RGD:9068941
G DBH dopamine beta-hydroxylase JBrowse link 9 50,004,806 50,024,130 RGD:13508589
RGD:9068941
G DECR1 2,4-dienoyl-CoA reductase 1 JBrowse link 29 35,495,348 35,544,955 RGD:13508589
RGD:9068941
G DIO2 iodothyronine deiodinase 2 JBrowse link 8 52,686,211 52,695,226 RGD:9068941
G DYNC1H1 dynein cytoplasmic 1 heavy chain 1 JBrowse link 8 69,997,021 70,064,886 RGD:13508589
RGD:9068941
G EBF2 EBF transcription factor 2 JBrowse link 25 31,478,361 31,671,018 RGD:13508589
RGD:9068941
G EHMT1 euchromatic histone lysine methyltransferase 1 JBrowse link 9 48,031,593 48,110,954 RGD:9068941
G ELOVL3 ELOVL fatty acid elongase 3 JBrowse link 28 14,756,019 14,759,893 RGD:9068941
G ELOVL6 ELOVL fatty acid elongase 6 JBrowse link 32 30,221,858 30,360,761 RGD:13508589
RGD:9068941
G EPAS1 endothelial PAS domain protein 1 JBrowse link 10 48,550,836 48,636,776 RGD:9068941
G ESRRG estrogen related receptor gamma JBrowse link 38 11,825,055 12,439,143 RGD:13508589
RGD:9068941
G FABP4 fatty acid binding protein 4 JBrowse link 29 28,651,550 28,656,255 RGD:9068941
G FABP5 fatty acid binding protein 5 JBrowse link 29 28,488,818 28,492,698 RGD:9068941
G FFAR4 free fatty acid receptor 4 JBrowse link 28 7,801,713 7,820,048 RGD:9068941
G FGF21 fibroblast growth factor 21 JBrowse link 1 107,571,449 107,576,630 RGD:13508589
RGD:9068941
G FH fumarate hydratase JBrowse link 7 32,900,250 32,927,436 RGD:13508589
RGD:9068941
G G0S2 G0/G1 switch 2 JBrowse link 7 8,335,699 8,336,615 RGD:9068941
G GADD45G growth arrest and DNA damage inducible gamma JBrowse link 1 96,745,001 96,746,535 RGD:9068941
G GATM glycine amidinotransferase JBrowse link 30 11,724,446 11,742,214 RGD:13508589
RGD:9068941
G GHRL ghrelin and obestatin prepropeptide JBrowse link 20 8,092,921 8,097,512 RGD:13508589
RGD:9068941
G GJA1 gap junction protein alpha 1 JBrowse link 1 60,941,772 60,944,694 RGD:13508589
RGD:9068941
G GNAS GNAS complex locus JBrowse link 24 43,643,409 43,658,641 RGD:9068941
G GPR3 G protein-coupled receptor 3 JBrowse link 2 72,882,127 72,885,369 RGD:9068941
G GRB10 growth factor receptor bound protein 10 JBrowse link 18 1,890,689 2,014,836 RGD:9068941
G HADH hydroxyacyl-CoA dehydrogenase JBrowse link 32 28,460,445 28,506,141 RGD:9068941
G HCRT hypocretin neuropeptide precursor JBrowse link 9 20,729,616 20,732,074 RGD:13508589
RGD:9068941
G HDAC3 histone deacetylase 3 JBrowse link 2 36,583,283 36,598,121 RGD:9068941
G HSF1 heat shock transcription factor 1 JBrowse link 13 37,724,741 37,745,259 RGD:13508589
RGD:9068941
G IGF1R insulin like growth factor 1 receptor JBrowse link 3 41,795,337 42,096,255 RGD:9068941
G IL13 interleukin 13 JBrowse link 11 20,957,870 20,961,391 RGD:9068941
G IL18 interleukin 18 JBrowse link 5 20,972,742 20,995,327 RGD:13508589
RGD:9068941
G IL4 interleukin 4 JBrowse link 11 20,972,693 20,981,539 RGD:9068941
G IL4R interleukin 4 receptor JBrowse link 6 19,254,183 19,280,973 RGD:9068941
G IRF4 interferon regulatory factor 4 JBrowse link 35 760,367 782,314 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 93,321,055 93,438,898 RGD:9068941
G KDM1A lysine demethylase 1A JBrowse link 2 76,313,742 76,375,716 RGD:9068941
G KDM3A lysine demethylase 3A JBrowse link 17 38,690,962 38,744,507 RGD:13508589
RGD:9068941
G KDM6B lysine demethylase 6B JBrowse link 5 32,689,000 32,711,026 RGD:13508589
RGD:9068941
G KSR2 kinase suppressor of ras 2 JBrowse link 26 13,986,172 14,394,236 RGD:9068941
G LCN2 lipocalin 2 JBrowse link 9 55,328,118 55,342,535 RGD:9068941
G LEP leptin JBrowse link 14 8,115,396 8,130,946 RGD:13508589
RGD:9068941
G LEPR leptin receptor JBrowse link 5 44,684,118 44,775,626 RGD:13508589
RGD:9068941
G LPIN1 lipin 1 JBrowse link 17 8,348,860 8,480,447 RGD:9068941
G MFAP2 microfibril associated protein 2 JBrowse link 2 81,217,197 81,223,726 RGD:9068941
G MFN2 mitofusin 2 JBrowse link 2 84,284,719 84,310,715 RGD:13508589
RGD:9068941
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 55,821,227 55,857,597 RGD:13508589
RGD:9068941
G OMA1 OMA1 zinc metallopeptidase JBrowse link 5 51,143,437 51,213,913 RGD:13508589
RGD:9068941
G OXT oxytocin/neurophysin I prepropeptide JBrowse link 24 18,193,381 18,194,232 RGD:9068941
G OXTR oxytocin receptor JBrowse link 20 9,358,797 9,382,308 RGD:9068941
G PDGFC platelet derived growth factor C JBrowse link 15 54,143,637 54,239,962 RGD:9068941
G PEMT phosphatidylethanolamine N-methyltransferase JBrowse link 5 41,871,685 41,960,831 RGD:13508589
RGD:9068941
G PER2 period circadian regulator 2 JBrowse link 25 48,716,499 48,761,617 RGD:9068941
G PHOX2B paired like homeobox 2B JBrowse link 13 38,865,963 38,869,912 RGD:13508589
RGD:9068941
G PLAC8B placenta specific 8 B JBrowse link 32 7,004,147 7,049,877 RGD:13508589
RGD:9068941
G PPARGC1A PPARG coactivator 1 alpha JBrowse link 3 85,645,942 86,284,570 RGD:13508589
RGD:9068941
G PPARGC1B PPARG coactivator 1 beta JBrowse link 4 59,167,041 59,278,977 RGD:13508589
RGD:9068941
G PRDM16 PR/SET domain 16 JBrowse link 5 57,805,951 58,018,817 RGD:9068941
G PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 JBrowse link 26 15,706,583 15,716,612 RGD:13508589
RGD:9068941
G PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2 JBrowse link 17 57,614,499 57,630,041 RGD:13508589
RGD:9068941
G PRLR prolactin receptor JBrowse link 4 73,147,919 73,280,970 RGD:9068941
G PTH2R parathyroid hormone 2 receptor JBrowse link 37 16,656,573 16,758,313 RGD:9068941
G SCD stearoyl-CoA desaturase JBrowse link 28 13,112,741 13,129,129 RGD:9068941
G SIRT6 sirtuin 6 JBrowse link 20 55,412,989 55,424,944 RGD:13508589
RGD:9068941
G SLN sarcolipin JBrowse link 5 24,710,057 24,716,834 RGD:9068941
G STAT6 signal transducer and activator of transcription 6 JBrowse link 10 1,232,515 1,247,011 RGD:13508589
RGD:9068941
G SYK spleen associated tyrosine kinase JBrowse link 1 95,903,501 95,955,577 RGD:9068941
G THRA thyroid hormone receptor alpha JBrowse link 9 22,469,466 22,493,445 RGD:9068941
G TRPM8 transient receptor potential cation channel subfamily M member 8 JBrowse link 25 45,261,092 45,357,560 RGD:9068941
G TRPV2 transient receptor potential cation channel subfamily V member 2 JBrowse link 5 39,488,155 39,512,454 RGD:13508589
RGD:9068941
G TSHR thyroid stimulating hormone receptor JBrowse link 8 53,327,280 53,482,898 RGD:9068941
G UCP1 uncoupling protein 1 JBrowse link 19 2,254,881 2,289,902 RGD:9068941
G UCP2 uncoupling protein 2 JBrowse link 21 24,304,410 24,311,392 RGD:13508589
RGD:9068941
G VEGFA vascular endothelial growth factor A JBrowse link 12 12,209,032 12,224,978 RGD:9068941
G YBX2 Y-box binding protein 2 JBrowse link 5 32,244,536 32,250,130 RGD:9068941
G ZBTB7B zinc finger and BTB domain containing 7B JBrowse link 7 42,468,376 42,482,219 RGD:9068941
G ZNF516 zinc finger protein 516 JBrowse link 1 3,275,255 3,400,761 RGD:9068941

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  biological_process 15735
    metabolic process 10450
      adaptive thermogenesis 149
        cold-induced thermogenesis + 142
        diet induced thermogenesis 9
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.