ONTOLOGY REPORT - ANNOTATIONS


Term:adaptive thermogenesis
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Accession:GO:1990845 term browser browse the term
Definition:The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.


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adaptive thermogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 1 178,321,108 178,337,810 RGD:2290270
G Pm20d1 peptidase M20 domain containing 1 JBrowse link 1 131,797,384 131,821,419 RGD:2290270
G Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) JBrowse link 8 83,290,348 83,298,456 RGD:2290270
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) JBrowse link 7 100,493,358 100,499,629 RGD:2290270
G Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) JBrowse link 7 100,472,991 100,486,432 RGD:2290270
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 3 89,377,644 89,394,815 RGD:2290270
diet induced thermogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenergic receptor, beta 1 JBrowse link 19 56,722,372 56,724,862 RGD:2290270
G Adrb2 adrenergic receptor, beta 2 JBrowse link 18 62,177,713 62,179,981 RGD:2290270
G Adrb3 adrenergic receptor, beta 3 JBrowse link 8 27,225,776 27,230,807 RGD:2290270
G Appl2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 JBrowse link 10 83,600,033 83,648,860 RGD:2290270
G Bmp8a bone morphogenetic protein 8a JBrowse link 4 123,312,645 123,343,252 RGD:2290270
G Bmp8b bone morphogenetic protein 8b JBrowse link 4 123,104,307 123,126,094 RGD:2290270
G Clic5 chloride intracellular channel 5 JBrowse link 17 44,134,664 44,280,169 RGD:2290270
G Gpr39 G protein-coupled receptor 39 JBrowse link 1 125,676,996 125,873,862 RGD:2290270
G Mc4r melanocortin 4 receptor JBrowse link 18 66,857,705 66,860,487 RGD:2290270
G Oma1 OMA1 zinc metallopeptidase JBrowse link 4 103,313,209 103,371,869 RGD:2290270
G Pparg peroxisome proliferator activated receptor gamma JBrowse link 6 115,360,877 115,490,404 RGD:2290270
G Sct secretin JBrowse link 7 141,278,329 141,279,171 RGD:2290270
G Sctr secretin receptor JBrowse link 1 120,006,899 120,063,539 RGD:2290270
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 11 73,234,149 73,261,322 RGD:2290270
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 5 114,622,152 114,658,435 RGD:2290270
G Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) JBrowse link 8 83,290,348 83,298,456 RGD:2290270
negative regulation of cold-induced thermogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd6 abhydrolase domain containing 6 JBrowse link 14 8,002,803 8,056,773 RGD:2290270
G Acot11 acyl-CoA thioesterase 11 JBrowse link 4 106,744,555 106,806,086 RGD:2290270
G Acot13 acyl-CoA thioesterase 13 JBrowse link 13 24,817,955 24,831,489 RGD:2290270
G Actn3 actinin alpha 3 JBrowse link 19 4,861,216 4,877,909 RGD:2290270
G Acvr2b activin receptor IIB JBrowse link 9 119,401,584 119,442,148 RGD:2290270
G Adam17 a disintegrin and metallopeptidase domain 17 JBrowse link 12 21,323,509 21,373,632 RGD:2290270
G Adamts5 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) JBrowse link 16 85,858,157 85,901,125 RGD:2290270
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 16 23,146,536 23,157,968 RGD:2290270
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 JBrowse link 19 20,601,982 20,643,462 RGD:2290270
G Arntl aryl hydrocarbon receptor nuclear translocator-like JBrowse link 7 113,178,470 113,314,126 RGD:2290270
G Arrdc3 arrestin domain containing 3 JBrowse link 13 80,883,338 80,896,042 RGD:2290270
G Atf4 activating transcription factor 4 JBrowse link 15 80,255,184 80,257,545 RGD:2290270
G Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A JBrowse link 18 67,343,564 67,367,794 RGD:2290270
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 10 127,290,793 127,296,291 RGD:2290270
G Dock7 dedicator of cytokinesis 7 JBrowse link 4 98,936,659 99,121,787 RGD:2290270
G Flcn folliculin JBrowse link 11 59,791,408 59,810,123 RGD:2290270
G Foxc2 forkhead box C2 JBrowse link 8 121,116,171 121,118,895 RGD:2290270
G Hoxc10 homeobox C10 JBrowse link 15 102,966,796 102,971,898 RGD:2290270
G Id1 inhibitor of DNA binding 1, HLH protein JBrowse link 2 152,736,234 152,737,410 RGD:2290270
G Il15 interleukin 15 JBrowse link 8 82,331,624 82,403,272 RGD:2290270
G Il18r1 interleukin 18 receptor 1 JBrowse link 1 40,465,552 40,500,854 RGD:2290270
G Ip6k1 inositol hexaphosphate kinase 1 JBrowse link 9 108,002,648 108,048,782 RGD:2290270
G Lama4 laminin, alpha 4 JBrowse link 10 38,965,515 39,110,188 RGD:2290270
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 JBrowse link 2 109,917,647 110,014,257 RGD:2290270
G Lnpep leucyl/cystinyl aminopeptidase JBrowse link 17 17,527,723 17,624,489 RGD:2290270
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 11 110,399,103 110,516,201 RGD:2290270
G Notch1 notch 1 JBrowse link 2 26,457,902 26,503,822 RGD:2290270
G Nova1 neuro-oncological ventral antigen 1 JBrowse link 12 46,694,517 46,819,194 RGD:2290270
G Nova2 neuro-oncological ventral antigen 2 JBrowse link 7 18,925,888 18,965,319 RGD:2290270
G Npr3 natriuretic peptide receptor 3 JBrowse link 15 11,839,896 11,907,371 RGD:2290270
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 JBrowse link 11 98,767,932 98,775,377 RGD:2290270
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 JBrowse link 7 44,549,616 44,553,968 RGD:2290270
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 JBrowse link 2 91,184,061 91,202,829 RGD:2290270
G Nrd1 nardilysin, N-arginine dibasic convertase, NRD convertase 1 JBrowse link 4 109,000,614 109,061,771 RGD:2290270
G Pctp phosphatidylcholine transfer protein JBrowse link 11 89,982,544 90,002,894 RGD:2290270
G Pgam5 phosphoglycerate mutase family member 5 JBrowse link 5 110,259,135 110,269,899 RGD:2290270
G Plcl1 phospholipase C-like 1 JBrowse link 1 55,405,946 55,754,285 RGD:2290270
G Plcl2 phospholipase C-like 2 JBrowse link 17 50,508,636 50,688,494 RGD:2290270
G Rb1 RB transcriptional corepressor 1 JBrowse link 14 73,194,453 73,325,885 RGD:2290270
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 5 53,466,115 53,657,445 RGD:2290270
G Rheb Ras homolog enriched in brain JBrowse link 5 24,802,823 24,842,361 RGD:2290270
G Stk11 serine/threonine kinase 11 JBrowse link 10 80,115,692 80,130,685 RGD:2290270
G Tfe3 transcription factor E3 JBrowse link X 7,762,537 7,775,202 RGD:2290270
G Tle3 transducin-like enhancer of split 3 JBrowse link 9 61,372,326 61,418,497 RGD:2290270
G Tlr4 toll-like receptor 4 JBrowse link 4 66,827,551 66,846,581 RGD:2290270
G Wnt10b wingless-type MMTV integration site family, member 10B JBrowse link 15 98,770,712 98,778,212 RGD:2290270
G Zfp423 zinc finger protein 423 JBrowse link 8 87,661,810 87,959,595 RGD:2290270
positive regulation of cold-induced thermogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acadl acyl-Coenzyme A dehydrogenase, long-chain JBrowse link 1 66,830,839 66,863,309 RGD:2290270
G Ache acetylcholinesterase JBrowse link 5 137,288,215 137,294,466 RGD:2290270
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 8 46,471,037 46,536,051 RGD:2290270
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 17 93,198,908 93,206,541 RGD:2290270
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 16 23,146,536 23,157,968 RGD:2290270
G Adipor1 adiponectin receptor 1 JBrowse link 1 134,415,378 134,433,351 RGD:2290270
G Adipor2 adiponectin receptor 2 JBrowse link 6 119,353,150 119,417,483 RGD:2290270
G Adrb1 adrenergic receptor, beta 1 JBrowse link 19 56,722,372 56,724,862 RGD:2290270
G Adrb2 adrenergic receptor, beta 2 JBrowse link 18 62,177,713 62,179,981 RGD:2290270
G Adrb3 adrenergic receptor, beta 3 JBrowse link 8 27,225,776 27,230,807 RGD:2290270
G Apc APC, WNT signaling pathway regulator JBrowse link 18 34,220,617 34,322,190 RGD:2290270
G Appl2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 JBrowse link 10 83,600,033 83,648,860 RGD:2290270
G Bscl2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) JBrowse link 19 8,837,467 8,848,683 RGD:2290270
G Cav1 caveolin 1, caveolae protein JBrowse link 6 17,306,335 17,341,328 RGD:2290270
G Ccr2 chemokine (C-C motif) receptor 2 JBrowse link 9 124,101,918 124,109,140 RGD:2290270
G Cd36 CD36 molecule JBrowse link 5 17,781,690 17,888,959 RGD:2290270
G Cebpb CCAAT/enhancer binding protein (C/EBP), beta JBrowse link 2 167,688,915 167,690,432 RGD:2290270
G Cmklr1 chemokine-like receptor 1 JBrowse link 5 113,612,355 113,650,474 RGD:2290270
G Cnot3 CCR4-NOT transcription complex, subunit 3 JBrowse link 7 3,645,269 3,661,109 RGD:2290270
G Cpt2 carnitine palmitoyltransferase 2 JBrowse link 4 107,903,982 107,923,589 RGD:2290270
G Cxcr4 chemokine (C-X-C motif) receptor 4 JBrowse link 1 128,588,199 128,592,311 RGD:2290270
G Dbh dopamine beta hydroxylase JBrowse link 2 27,165,507 27,183,204 RGD:2290270
G Decr1 2,4-dienoyl CoA reductase 1, mitochondrial JBrowse link 4 15,917,240 15,945,507 RGD:2290270
G Dio2 deiodinase, iodothyronine, type II JBrowse link 12 90,724,552 90,739,037 RGD:2290270
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 JBrowse link 12 110,601,395 110,666,944 RGD:2290270
G Ebf2 early B cell factor 2 JBrowse link 14 67,233,292 67,430,952 RGD:2290270
G Ehmt1 euchromatic histone methyltransferase 1 JBrowse link 2 24,790,769 24,919,643 RGD:2290270
G Elovl3 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3 JBrowse link 19 46,131,899 46,135,694 RGD:2290270
G Elovl6 ELOVL family member 6, elongation of long chain fatty acids (yeast) JBrowse link 3 129,532,386 129,638,495 RGD:2290270
G Epas1 endothelial PAS domain protein 1 JBrowse link 17 86,753,864 86,833,410 RGD:2290270
G Esrrg estrogen-related receptor gamma JBrowse link 1 187,608,791 188,214,884 RGD:2290270
G Fabp4 fatty acid binding protein 4, adipocyte JBrowse link 3 10,204,342 10,208,602 RGD:2290270
G Fabp5 fatty acid binding protein 5, epidermal JBrowse link 3 10,012,585 10,016,610 RGD:2290270
G Ffar4 free fatty acid receptor 4 JBrowse link 19 38,097,079 38,114,263 RGD:2290270
G Fgf21 fibroblast growth factor 21 JBrowse link 7 45,613,890 45,619,350 RGD:2290270
G Fh1 fumarate hydratase 1 JBrowse link 1 175,601,378 175,625,635 RGD:2290270
G G0s2 G0/G1 switch gene 2 JBrowse link 1 193,272,160 193,273,188 RGD:2290270
G Gadd45g growth arrest and DNA-damage-inducible 45 gamma JBrowse link 13 51,846,675 51,848,475 RGD:2290270
G Gatm glycine amidinotransferase (L-arginine:glycine amidinotransferase) JBrowse link 2 122,594,473 122,611,277 RGD:2290270
G Ghrl ghrelin JBrowse link 6 113,716,119 113,719,911 RGD:2290270
G Gja1 gap junction protein, alpha 1 JBrowse link 10 56,377,300 56,390,419 RGD:2290270
G Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus JBrowse link 2 174,284,306 174,346,744 RGD:2290270
G Gpr3 G-protein coupled receptor 3 JBrowse link 4 133,209,340 133,212,536 RGD:2290270
G Grb10 growth factor receptor bound protein 10 JBrowse link 11 11,930,499 12,037,422 RGD:2290270
G Hadh hydroxyacyl-Coenzyme A dehydrogenase JBrowse link 3 131,233,419 131,272,101 RGD:2290270
G Hcrt hypocretin JBrowse link 11 100,761,693 100,762,931 RGD:2290270
G Hdac3 histone deacetylase 3 JBrowse link 18 37,936,971 37,954,988 RGD:2290270
G Hsf1 heat shock factor 1 JBrowse link 15 76,477,367 76,500,982 RGD:2290270
G Igf1r insulin-like growth factor I receptor JBrowse link 7 67,951,833 68,233,668 RGD:2290270
G Il13 interleukin 13 JBrowse link 11 53,631,323 53,634,702 RGD:2290270
G Il18 interleukin 18 JBrowse link 9 50,554,705 50,581,841 RGD:2290270
G Il4 interleukin 4 JBrowse link 11 53,612,460 53,618,665 RGD:2290270
G Il4ra interleukin 4 receptor, alpha JBrowse link 7 125,552,282 125,579,474 RGD:2290270
G Irf4 interferon regulatory factor 4 JBrowse link 13 30,749,208 30,766,982 RGD:2290270
G Jak2 Janus kinase 2 JBrowse link 19 29,251,708 29,313,080 RGD:2290270
G Kdm1a lysine (K)-specific demethylase 1A JBrowse link 4 136,550,533 136,602,790 RGD:2290270
G Kdm3a lysine (K)-specific demethylase 3A JBrowse link 6 71,588,970 71,633,009 RGD:2290270
G Kdm6b KDM1 lysine (K)-specific demethylase 6B JBrowse link 11 69,398,508 69,418,147 RGD:2290270
G Ksr2 kinase suppressor of ras 2 JBrowse link 5 117,413,221 117,775,004 RGD:2290270
G Lcn2 lipocalin 2 JBrowse link 2 32,384,637 32,387,739 RGD:2290270
G Lep leptin JBrowse link 6 29,060,195 29,073,877 RGD:2290270
G Lepr leptin receptor JBrowse link 4 101,717,134 101,815,354 RGD:2290270
G Lpin1 lipin 1 JBrowse link 12 16,535,669 16,646,969 RGD:2290270
G Mfap2 microfibrillar-associated protein 2 JBrowse link 4 141,010,424 141,015,984 RGD:2290270
G Mfn2 mitofusin 2 JBrowse link 4 147,873,586 147,904,909 RGD:2290270
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) JBrowse link X 101,640,011 101,684,351 RGD:2290270
G Oma1 OMA1 zinc metallopeptidase JBrowse link 4 103,313,209 103,371,869 RGD:2290270
G Oxt oxytocin JBrowse link 2 130,574,520 130,577,054 RGD:2290270
G Oxtr oxytocin receptor JBrowse link 6 112,473,684 112,491,308 RGD:2290270
G Pdgfc platelet-derived growth factor, C polypeptide JBrowse link 3 81,035,887 81,214,040 RGD:2290270
G Pemt phosphatidylethanolamine N-methyltransferase JBrowse link 11 59,970,614 60,046,510 RGD:2290270
G Per2 period circadian clock 2 JBrowse link 1 91,415,977 91,459,402 RGD:2290270
G Phox2b paired-like homeobox 2b JBrowse link 5 67,094,397 67,099,126 RGD:2290270
G Plac8 placenta-specific 8 JBrowse link 5 100,551,589 100,572,251 RGD:2290270
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha JBrowse link 5 51,454,249 52,116,058 RGD:2290270
G Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta JBrowse link 18 61,291,445 61,401,462 RGD:2290270
G Prdm16 PR domain containing 16 JBrowse link 4 154,316,122 154,636,873 RGD:2290270
G Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit JBrowse link 5 116,013,586 116,024,503 RGD:2290270
G Prkab2 protein kinase, AMP-activated, beta 2 non-catalytic subunit JBrowse link 3 97,658,212 97,673,812 RGD:2290270
G Prlr prolactin receptor JBrowse link 15 10,177,238 10,349,180 RGD:2290270
G Pth2r parathyroid hormone 2 receptor JBrowse link 1 65,280,282 65,389,625 RGD:2290270
G Scd1 stearoyl-Coenzyme A desaturase 1 JBrowse link 19 44,394,450 44,407,709 RGD:2290270
G Sirt6 sirtuin 6 JBrowse link 10 81,621,786 81,627,797 RGD:2290270
G Sln sarcolipin JBrowse link 9 53,850,251 53,853,849 RGD:2290270
G Stat6 signal transducer and activator of transcription 6 JBrowse link 10 127,642,039 127,660,987 RGD:2290270
G Syk spleen tyrosine kinase JBrowse link 13 52,582,329 52,648,792 RGD:2290270
G Thra thyroid hormone receptor alpha JBrowse link 11 98,741,776 98,769,006 RGD:2290270
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 JBrowse link 1 88,306,712 88,388,853 RGD:2290270
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 JBrowse link 11 62,574,486 62,600,305 RGD:2290270
G Tshr thyroid stimulating hormone receptor JBrowse link 12 91,400,993 91,540,509 RGD:2290270
G Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) JBrowse link 8 83,290,348 83,298,456 RGD:2290270
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) JBrowse link 7 100,493,358 100,499,629 RGD:2290270
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:2290270
G Ybx2 Y box protein 2 JBrowse link 11 69,935,834 69,941,604 RGD:2290270
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 3 89,377,644 89,394,815 RGD:2290270
G Zfp516 zinc finger protein 516 JBrowse link 18 82,910,522 83,005,314 RGD:2290270

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  biological_process 22960
    metabolic process 10235
      adaptive thermogenesis 155
        cold-induced thermogenesis + 142
        diet induced thermogenesis 16
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.