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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular smooth muscle cell dedifferentiation
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Accession:GO:1990936 term browser browse the term
Definition:The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.


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positive regulation of vascular smooth muscle cell dedifferentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1624291
RGD:1600115
regulation of vascular smooth muscle cell dedifferentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Olfm2 olfactomedin 2 JBrowse link 8 21,684,307 21,762,000 RGD:13441204

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  biological_process 19317
    developmental process 6647
      dedifferentiation 9
        cell dedifferentiation 9
          cell dedifferentiation involved in phenotypic switching 2
            vascular smooth muscle cell dedifferentiation 2
              negative regulation of vascular smooth muscle cell dedifferentiation 0
              positive regulation of vascular smooth muscle cell dedifferentiation 1
              regulation of vascular smooth muscle cell dedifferentiation + 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.