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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of double-strand break repair via homologous recombination
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Accession:GO:2000042 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination.
Synonyms:exact_synonym: negative regulation of HDR;   negative regulation of HRR;   negative regulation of Rad51-dependent recombinational repair;   negative regulation of Rhp51-dependent recombinational repair;   negative regulation of homologous recombinational repair;   negative regulation of homology-directed repair


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negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CGAS cyclic GMP-AMP synthase JBrowse link 1 92,483,253 92,500,376 RGD:14298760
G FANCB FA complementation group B JBrowse link X 11,386,360 11,408,958 RGD:14298760
G FBH1 F-box DNA helicase 1 JBrowse link 10 65,060,714 65,108,975 RGD:14298760
G HELB DNA helicase B JBrowse link 5 30,645,378 30,696,488 RGD:14298760
G KLHL15 kelch like family member 15 JBrowse link X 20,088,208 20,130,452 RGD:14298760
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 6 71,773,680 71,779,192 RGD:14298760
G MAGEF1 MAGE family member F1 JBrowse link 13 122,600,984 122,602,700 RGD:14298760
G PARPBP PARP1 binding protein JBrowse link 5 82,018,857 82,091,946 RGD:14298760
G POLQ DNA polymerase theta JBrowse link 13 138,962,634 139,108,499 RGD:14298760
G RADX RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 87,025,603 87,103,503 RGD:14298760
G RECQL5 RecQ like helicase 5 JBrowse link 12 5,732,336 5,770,136 RGD:14298760
G RIF1 replication timing regulatory factor 1 JBrowse link 15 769,518 832,036 RGD:14298760
G RMI2 RecQ mediated genome instability 2 JBrowse link 3 31,807,717 31,814,869 RGD:14298760
G SHLD1 shieldin complex subunit 1 JBrowse link 17 14,610,723 14,706,082 RGD:14298760
G SHLD2 shieldin complex subunit 2 JBrowse link 14 88,005,599 88,121,155 RGD:14298760
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 JBrowse link 6 103,809,732 103,986,057 RGD:14298760
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 1 127,958,500 128,032,370 RGD:14298760
G UBQLN4 ubiquilin 4 JBrowse link 4 93,976,386 93,994,830 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16411
    metabolic process 10434
      negative regulation of metabolic process 3022
        negative regulation of macromolecule metabolic process 2757
          negative regulation of DNA metabolic process 121
            negative regulation of DNA recombination 40
              negative regulation of double-strand break repair via homologous recombination 18
                negative regulation of double-strand break repair via break-induced replication 0
Path 2
Term Annotations click to browse term
  biological_process 16411
    metabolic process 10434
      cellular metabolic process 9428
        cellular aromatic compound metabolic process 4993
          nucleobase-containing compound metabolic process 4795
            nucleic acid metabolic process 4388
              DNA metabolic process 808
                regulation of DNA metabolic process 379
                  negative regulation of DNA metabolic process 121
                    negative regulation of DNA repair 32
                      negative regulation of double-strand break repair 31
                        negative regulation of double-strand break repair via homologous recombination 18
                          negative regulation of double-strand break repair via break-induced replication 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.