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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of DNA-templated transcription, initiation
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Accession:GO:2000143 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation.
Synonyms:exact_synonym: negative regulation of DNA-dependent transcription, initiation;   negative regulation of initiation of DNA-dependent transcription


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negative regulation of DNA-templated transcription, initiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Morc1 MORC family CW-type zinc finger 1 ISO MGI:MGI:1857787 (MGI:MGI:5694015|PMID:25503965) RGD PMID:25503965 MGI:MGI:5694015 NCBI chr11:54,762,654...55,044,581
Ensembl chr11:54,762,654...55,044,581
JBrowse link
G Thra thyroid hormone receptor alpha ISO (PMID:8524305) RGD PMID:8524305 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
negative regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 ISO (PMID:8006019) RGD PMID:8006019 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Thra thyroid hormone receptor alpha IEA
ISO
GO_REF:0000107
(PMID:8524305)
Ensembl
RGD
PMID:8524305 GO_REF:0000107 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
negative regulation of transcription initiation from RNA polymerase II promoter term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnbip1 catenin, beta-interacting protein 1 ISO (MGI:MGI:4821083|PMID:11751639) RGD PMID:11751639 MGI:MGI:4821083 NCBI chr 5:166,464,170...166,513,030
Ensembl chr 5:166,464,252...166,513,027
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 ISO (PMID:10692439) RGD PMID:10692439 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Zfp451 zinc finger protein 451 ISO (PMID:24324267) RGD PMID:24324267 NCBI chr 9:38,395,464...38,451,585
Ensembl chr 9:38,396,449...38,451,656
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      negative regulation of metabolic process 3315
        negative regulation of macromolecule metabolic process 3042
          negative regulation of gene expression 2157
            negative regulation of transcription, DNA-templated 1341
              negative regulation of DNA-templated transcription, initiation 6
                negative regulation of transcription initiation from RNA polymerase II promoter + 5
Path 2
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      cellular metabolic process 11064
        cellular aromatic compound metabolic process 5708
          nucleobase-containing compound metabolic process 5483
            nucleic acid metabolic process 4980
              RNA metabolic process 4470
                RNA biosynthetic process 3478
                  regulation of RNA biosynthetic process 3343
                    regulation of nucleic acid-templated transcription 3338
                      negative regulation of nucleic acid-templated transcription 1374
                        negative regulation of transcription, DNA-templated 1341
                          negative regulation of DNA-templated transcription, initiation 6
                            negative regulation of transcription initiation from RNA polymerase II promoter + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.