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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of DNA-templated transcription, initiation
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Accession:GO:2000144 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation.
Synonyms:exact_synonym: positive regulation of DNA-dependent transcription, initiation;   positive regulation of initiation of DNA-dependent transcription
 related_synonym: transactivation;   transcriptional transactivation


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positive regulation of DNA-templated transcription, initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bclaf1 BCL2-associated transcription factor 1 ISO (PMID:17938203) RGD PMID:17938203 NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha ISO (PMID:28186500) RGD PMID:28186500 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Ctnnb1 catenin beta 1 ISO
IEA
(MGI:MGI:5428344|PMID:22723415)
GO_REF:0000107
RGD
Ensembl
PMID:22723415 GO_REF:0000107, MGI:MGI:5428344 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit ISO (PMID:23027619) RGD PMID:23027619 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO (PMID:23027619) RGD PMID:23027619 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Mitf melanocyte inducing transcription factor ISO (PMID:12204775), (PMID:8995290) RGD PMID:8995290, PMID:12204775 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Setx senataxin ISO (PMID:21700224) RGD PMID:21700224 NCBI chr 3:7,680,430...7,731,815
Ensembl chr 3:7,686,503...7,730,539
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:17332325) RGD PMID:17332325 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
positive regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor ISO (MGI:MGI:62922|PMID:8215422) RGD PMID:8215422 MGI:MGI:62922 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Cand1 cullin-associated and neddylation-dissociated 1 IDA PMID:10567521 UniProt PMID:10567521 RGD:8553447 NCBI chr 7:62,124,362...62,162,451
Ensembl chr 7:62,124,362...62,162,453
JBrowse link
G Creb1 cAMP responsive element binding protein 1 IMP RGD PMID:16891311 RGD:1625706 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Esr1 estrogen receptor 1 IEA
ISO
GO_REF:0000107
(PMID:9841876)
Ensembl
RGD
PMID:9841876 GO_REF:0000107 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO MGI:MGI:2158690 (MGI:MGI:5317044|PMID:21245044) RGD PMID:21245044 MGI:MGI:5317044 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:9,867,132...9,881,383
Ensembl chr 4:9,867,101...9,881,484
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:79,876,938...79,882,319
Ensembl chr 3:79,876,938...79,882,319
JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:84,978,220...84,986,536
Ensembl chr 1:84,978,206...84,986,581
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:94,445,877...94,451,811
Ensembl chr10:94,445,877...94,451,811
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914
JBrowse link
G Tp53 tumor protein p53 ISO (PMID:24289924) RGD PMID:24289924 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Wnt10b Wnt family member 10B ISO (MGI:MGI:3820325|PMID:19056892) RGD PMID:19056892 MGI:MGI:3820325 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268
JBrowse link
positive regulation of transcription initiation from RNA polymerase II promoter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx36 DEAH-box helicase 36 ISS
ISO
GO_REF:0000024
(PMID:21993297)
UniProt
RGD
PMID:21993297 GO_REF:0000024 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO (MGI:MGI:5314556|PMID:22323595) RGD PMID:22323595 MGI:MGI:5314556 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor ISO MGI:MGI:1932102|MGI:MGI:99135 (MGI:MGI:5314556|PMID:22323595) RGD PMID:22323595 MGI:MGI:5314556 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Gtf2b general transcription factor IIB ISS
ISO
IEA
GO_REF:0000024
(PMID:12931194), (PMID:9420329)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:9420329, PMID:12931194 GO_REF:0000024, GO_REF:0000107 NCBI chr 2:248,709,433...248,727,741
Ensembl chr 2:248,715,281...248,727,741
JBrowse link
G Hnf1a HNF1 homeobox A ISO UniProtKB:P35680 (PMID:15355349) RGD PMID:15355349 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hnf1b HNF1 homeobox B ISO (PMID:15355349) RGD PMID:15355349 NCBI chr10:71,159,863...71,218,902
Ensembl chr10:71,159,869...71,218,902
JBrowse link
G Irf8 interferon regulatory factor 8 NOT ISO (MGI:MGI:5448615|PMID:22942423) RGD PMID:22942423 MGI:MGI:5448615 NCBI chr19:54,314,859...54,336,643
Ensembl chr19:54,314,865...54,336,640
JBrowse link
G Med1 mediator complex subunit 1 ISO
ISS
(PMID:12218053), (PMID:16314496)
GO_REF:0000024
RGD
UniProt
PMID:12218053, PMID:16314496 GO_REF:0000024 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Med12 mediator complex subunit 12 ISO
IEA
(PMID:12218053)
GO_REF:0000107
RGD
Ensembl
PMID:12218053 GO_REF:0000107 NCBI chr  X:71,174,653...71,197,812
Ensembl chr  X:71,174,699...71,197,812
JBrowse link
G Med13 mediator complex subunit 13 ISO
IEA
(PMID:12218053)
GO_REF:0000107
RGD
Ensembl
PMID:12218053 GO_REF:0000107 NCBI chr10:73,702,327...73,787,084
Ensembl chr10:73,702,327...73,787,083
JBrowse link
G Med14 mediator complex subunit 14 ISO
IEA
(PMID:12218053)
GO_REF:0000107
RGD
Ensembl
PMID:12218053 GO_REF:0000107 NCBI chr  X:10,964,035...11,082,403
Ensembl chr  X:10,963,809...11,082,565
JBrowse link
G Med16 mediator complex subunit 16 ISO
IEA
(PMID:12218053)
GO_REF:0000107
RGD
Ensembl
PMID:12218053 GO_REF:0000107 NCBI chr 7:12,619,739...12,632,241
Ensembl chr 7:12,542,713...12,632,298
JBrowse link
G Med17 mediator complex subunit 17 ISO (PMID:12218053) RGD PMID:12218053 NCBI chr 8:13,522,257...13,835,302
Ensembl chr 8:13,819,563...13,835,168
JBrowse link
G Med24 mediator complex subunit 24 ISO (PMID:12218053) RGD PMID:12218053 NCBI chr10:86,620,166...86,658,014
Ensembl chr10:86,620,160...86,645,529
JBrowse link
G Med30 mediator complex subunit 30 ISO
IEA
(PMID:12218053)
GO_REF:0000107
RGD
Ensembl
PMID:12218053 GO_REF:0000107 NCBI chr 7:92,234,584...92,260,019
Ensembl chr 7:92,234,597...92,256,100
JBrowse link
G Med4 mediator complex subunit 4 ISO
IEA
(PMID:12218053)
GO_REF:0000107
RGD
Ensembl
PMID:12218053 GO_REF:0000107 NCBI chr15:55,406,543...55,416,816
Ensembl chr15:55,406,543...55,416,815
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO (MGI:MGI:6377809|PMID:26691508) RGD PMID:26691508 MGI:MGI:6377809 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nkx2-5 NK2 homeobox 5 ISO
IEA
(MGI:MGI:83559|PMID:8887666)
GO_REF:0000107
RGD
Ensembl
PMID:8887666 GO_REF:0000107, MGI:MGI:83559 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Paxip1 PAX interacting protein 1 ISO (PMID:17925232)
(MGI:MGI:4354659|PMID:19583951), (MGI:MGI:4821506|PMID:20671152)
RGD PMID:17925232, PMID:19583951, PMID:20671152 MGI:MGI:4354659, MGI:MGI:4821506 NCBI chr 4:3,956,931...4,008,326
Ensembl chr 4:3,959,640...4,008,326
JBrowse link
G Pou5f1 POU class 5 homeobox 1 ISO (MGI:MGI:6377809|PMID:26691508) RGD PMID:26691508 MGI:MGI:6377809 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Srf serum response factor ISO (PMID:8887666) RGD PMID:8887666 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Sub1 SUB1 regulator of transcription IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:62,019,902...62,034,704
Ensembl chr 2:62,022,567...62,034,628
JBrowse link
G Taf6 TATA-box binding protein associated factor 6 ISO (PMID:11583621), (PMID:18628956) RGD PMID:11583621, PMID:18628956 NCBI chr12:19,320,269...19,328,706
Ensembl chr12:19,320,271...19,328,637
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor ISO MGI:MGI:1100494 (MGI:MGI:5314556|PMID:22323595) RGD PMID:22323595 MGI:MGI:5314556 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      positive regulation of metabolic process 4083
        positive regulation of macromolecule metabolic process 3765
          positive regulation of gene expression 2524
            positive regulation of transcription, DNA-templated 1698
              positive regulation of DNA-templated transcription, initiation 44
                positive regulation of transcription initiation from RNA polymerase II promoter + 36
Path 2
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      cellular metabolic process 11064
        cellular aromatic compound metabolic process 5708
          nucleobase-containing compound metabolic process 5483
            nucleic acid metabolic process 4980
              RNA metabolic process 4470
                RNA biosynthetic process 3478
                  regulation of RNA biosynthetic process 3343
                    regulation of nucleic acid-templated transcription 3338
                      positive regulation of nucleic acid-templated transcription 1758
                        positive regulation of transcription, DNA-templated 1698
                          positive regulation of DNA-templated transcription, initiation 44
                            positive regulation of transcription initiation from RNA polymerase II promoter + 36
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.