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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of neural precursor cell proliferation
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Accession:GO:2000178 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.


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negative regulation of neural precursor cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 ISO (MGI:MGI:6271956|PMID:28965332) RGD PMID:28965332 MGI:MGI:6271956 NCBI chr 7:26,256,179...26,306,128
Ensembl chr 7:26,256,459...26,306,126
JBrowse link
G Btg2 BTG anti-proliferation factor 2 ISO MGI:MGI:3525505 (MGI:MGI:4418391|PMID:20020054) RGD PMID:20020054 MGI:MGI:4418391 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IMP RGD PMID:20940264 RGD:4889880 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Gata2 GATA binding protein 2 ISO MGI:MGI:1857743 (MGI:MGI:3629248|PMID:16672344)
(PMID:16672344)
RGD PMID:16672344 MGI:MGI:3629248 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488
JBrowse link
G Il1b interleukin 1 beta IDA RGD PMID:22270046 RGD:6482669 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Ilk integrin-linked kinase ISO MGI:MGI:103040|MGI:MGI:3653044|MGI:MGI:3767432 (MGI:MGI:5561134|PMID:24719101) RGD PMID:24719101 MGI:MGI:5561134 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Kdm2b lysine demethylase 2B ISO (MGI:MGI:4949568|PMID:21220025) RGD PMID:21220025 MGI:MGI:4949568 NCBI chr12:39,021,924...39,161,954
Ensembl chr12:39,078,119...39,161,956
JBrowse link
G Lims1 LIM zinc finger domain containing 1 ISO MGI:MGI:2385067 (MGI:MGI:5561134|PMID:24719101) RGD PMID:24719101 MGI:MGI:5561134 NCBI chr20:27,895,981...28,004,767
Ensembl chr20:27,954,433...28,002,082
JBrowse link
G Lims2 LIM zinc finger domain containing 2 ISO MGI:MGI:1195263 (MGI:MGI:5561134|PMID:24719101) RGD PMID:24719101 MGI:MGI:5561134 NCBI chr18:24,707,951...24,746,159
Ensembl chr18:24,708,115...24,746,159
JBrowse link
G Nr2e1 nuclear receptor subfamily 2, group E, member 1 ISO MGI:MGI:2151350 (MGI:MGI:3527227|PMID:12527005), (MGI:MGI:3629819|PMID:15385616) RGD PMID:12527005, PMID:15385616 MGI:MGI:3527227, MGI:MGI:3629819 NCBI chr20:47,286,843...47,306,318
Ensembl chr20:47,288,137...47,306,318
JBrowse link
G Pax6 paired box 6 ISO
IEA
MGI:MGI:1856155 (MGI:MGI:5494876|PMID:23622063)
GO_REF:0000107
RGD
Ensembl
PMID:23622063 GO_REF:0000107, MGI:MGI:5494876 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 ISO MGI:MGI:2445403 (MGI:MGI:3701731|PMID:16858399) RGD PMID:16858399 MGI:MGI:3701731 NCBI chr 3:8,189,594...8,307,077
Ensembl chr 3:8,192,575...8,304,976
JBrowse link
G Slc16a2 solute carrier family 16 member 2 ISO
IEA
(PMID:19022891)
GO_REF:0000107
RGD
Ensembl
PMID:19022891 GO_REF:0000107 NCBI chr  X:74,578,600...74,706,068
Ensembl chr  X:74,577,131...74,706,214
JBrowse link
G Spint1 serine peptidase inhibitor, Kunitz type 1 IMP RGD PMID:23409135 RGD:10043095 NCBI chr 3:111,049,132...111,061,991
Ensembl chr 3:111,049,118...111,062,011
JBrowse link
G Spint2 serine peptidase inhibitor, Kunitz type, 2 IMP RGD PMID:23409135 RGD:10043095 NCBI chr 1:87,199,373...87,221,826
Ensembl chr 1:87,199,313...87,221,892
JBrowse link
negative regulation of cell proliferation in midbrain term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt5a Wnt family member 5A ISO
IEA
(MGI:MGI:3829860|PMID:18953410)
GO_REF:0000107
RGD
Ensembl
PMID:18953410 GO_REF:0000107, MGI:MGI:3829860 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
negative regulation of cerebellar granule cell precursor proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cend1 cell cycle exit and neuronal differentiation 1 ISO MGI:MGI:4831137 (MGI:MGI:4830814|PMID:20153830) RGD PMID:20153830 MGI:MGI:4830814 NCBI chr 1:214,407,072...214,410,069
Ensembl chr 1:214,408,100...214,408,549
JBrowse link
G Slc6a4 solute carrier family 6 member 4 IMP RGD PMID:18573488 RGD:4889489 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
negative regulation of neuroblast proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor ISO (MGI:MGI:2664423|PMID:12798291) RGD PMID:12798291 MGI:MGI:2664423 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Cd24 CD24 molecule ISO MGI:MGI:2179996 (MGI:MGI:2178911|PMID:11978835) RGD PMID:11978835 MGI:MGI:2178911 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Ctnna1 catenin alpha 1 ISO MGI:MGI:108075|MGI:MGI:2176173|MGI:MGI:2677796 (MGI:MGI:3619284|PMID:16543460) RGD PMID:16543460 MGI:MGI:3619284 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
JBrowse link
G Kctd11 potassium channel tetramerization domain containing 11 ISO (MGI:MGI:3603087|PMID:16148242) RGD PMID:16148242 MGI:MGI:3603087 NCBI chr10:56,489,552...56,491,715
Ensembl chr10:56,489,552...56,491,715
JBrowse link
G Nf1 neurofibromin 1 ISO
ISS
IEA
MGI:MGI:1857444 (MGI:MGI:66069|PMID:7926784)
GO_REF:0000024
GO_REF:0000107
RGD
HGNC
Ensembl
PMID:7926784 GO_REF:0000024, GO_REF:0000107, MGI:MGI:66069 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Ptn pleiotrophin ISS
ISO
GO_REF:0000024
(MGI:MGI:3045656|PMID:15121180)
UniProt
RGD
PMID:15121180 GO_REF:0000024, MGI:MGI:3045656 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IDA RGD PMID:16177030 RGD:1579761 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tp53 tumor protein p53 ISO MGI:MGI:97306 (MGI:MGI:1203920|PMID:9608530) RGD PMID:9608530 MGI:MGI:1203920 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Vax1 ventral anterior homeobox 1 ISO MGI:MGI:1859863 (MGI:MGI:3531600|PMID:15590934) RGD PMID:15590934 MGI:MGI:3531600 NCBI chr 1:280,334,897...280,338,813
Ensembl chr 1:280,334,897...280,338,813
JBrowse link
negative regulation of oligodendrocyte progenitor proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt2 sirtuin 2 IMP PMID:17344398 UniProt PMID:17344398 RGD:8553877 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    negative regulation of biological process 5696
      negative regulation of cellular process 5144
        negative regulation of cell population proliferation 733
          negative regulation of neural precursor cell proliferation 28
            negative regulation of cell proliferation in dorsal spinal cord 0
            negative regulation of cell proliferation in midbrain 1
            negative regulation of cerebellar granule cell precursor proliferation + 2
            negative regulation of neuroblast proliferation + 9
            negative regulation of oligodendrocyte progenitor proliferation 1
Path 2
Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological process 13071
        negative regulation of biological process 5696
          negative regulation of cellular process 5144
            negative regulation of cell population proliferation 733
              negative regulation of neural precursor cell proliferation 28
                negative regulation of cell proliferation in dorsal spinal cord 0
                negative regulation of cell proliferation in midbrain 1
                negative regulation of cerebellar granule cell precursor proliferation + 2
                negative regulation of neuroblast proliferation + 9
                negative regulation of oligodendrocyte progenitor proliferation 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.