ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of reproductive process
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Accession:GO:2000242 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process.


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meiotic recombination checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hormad1 HORMA domain containing 1 JBrowse link 2 197,681,820 197,720,197 RGD:1600115
RGD:1624291
G Rad1 RAD1 checkpoint DNA exonuclease JBrowse link 2 60,461,513 60,469,646 RGD:1624291
RGD:1600115
G Trip13 thyroid hormone receptor interactor 13 JBrowse link 1 31,967,980 32,012,923 RGD:13792537
meiotic spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ttk Ttk protein kinase JBrowse link 8 91,368,065 91,405,995 RGD:1624291
RGD:1600115
negative regulation of acrosome reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Spink13 serine peptidase inhibitor, Kazal type 13 (putative) JBrowse link 18 57,935,271 58,081,096 RGD:8553255
negative regulation of binding of sperm to zona pellucida term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Astl astacin like metalloendopeptidase JBrowse link 3 119,783,717 119,799,450 RGD:1624291
RGD:13792537
G Zp3 zona pellucida glycoprotein 3 JBrowse link 12 23,735,225 23,752,734 RGD:1624291
RGD:1600115
G Zp4 zona pellucida glycoprotein 4 JBrowse link 17 65,497,359 65,503,912 RGD:1600115
RGD:1624291
negative regulation of cell differentiation involved in embryonic placenta development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
RGD:1600115
negative regulation of epithelial cell proliferation involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:1624291
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:1624291
RGD:1600115
G Eaf2 ELL associated factor 2 JBrowse link 11 66,878,658 66,923,092 RGD:1624291
RGD:1600115
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1600115
RGD:1624291
G Serpinf1 serpin family F member 1 JBrowse link 10 62,241,750 62,254,145 RGD:1624291
RGD:1600115
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:1624291
RGD:1600115
G Wdr77 WD repeat domain 77 JBrowse link 2 208,577,292 208,587,263 RGD:1624291
negative regulation of establishment of Sertoli cell barrier term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:10046056
negative regulation of female gonad development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 JBrowse link 3 22,998,900 23,020,441 RGD:1624291
RGD:1600115
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
RGD:1600115
G Zfpm2 zinc finger protein, multitype 2 JBrowse link 7 79,471,277 79,964,405 RGD:1624291
negative regulation of flagellated sperm motility term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eppin epididymal peptidase inhibitor JBrowse link 3 161,043,761 161,050,550 RGD:1624291
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:9590208
G Semg1 semenogelin 1 JBrowse link 3 160,627,609 160,630,457 RGD:1624291
G Svs3a seminal vesicle secretory protein 3A JBrowse link 3 159,082,547 159,084,618 RGD:1600115
G Svs3b seminal vesicle secretory protein 3B JBrowse link 3 159,082,346 159,084,621 RGD:1600115
negative regulation of male germ cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hpgds hematopoietic prostaglandin D synthase JBrowse link 4 95,945,356 95,970,666 RGD:1624291
RGD:1600115
G Prdx4 peroxiredoxin 4 JBrowse link X 43,495,453 43,512,994 RGD:1624291
RGD:1600115
G Ptgdr2 prostaglandin D2 receptor 2 JBrowse link 1 226,976,455 226,995,641 RGD:1624291
RGD:1600115
G Ptgds prostaglandin D2 synthase JBrowse link 3 2,686,125 2,689,059 RGD:1624291
RGD:1600115
negative regulation of male gonad development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asmt acetylserotonin O-methyltransferase JBrowse link 12 18,521,383 18,527,036 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
negative regulation of meiotic cell cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:1600115
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:1624291
RGD:1600115
G Npr2 natriuretic peptide receptor 2 JBrowse link 5 59,128,186 59,147,321 RGD:1624291
RGD:1600115
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:2312556
G Prkacb protein kinase cAMP-activated catalytic subunit beta JBrowse link 2 252,602,197 252,691,886 RGD:2312556
negative regulation of meiotic cell cycle phase transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ovol1 ovo like transcriptional repressor 1 JBrowse link 1 220,927,309 220,938,814 RGD:1624291
RGD:1600115
negative regulation of meiotic cell cycle process involved in oocyte maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:1624291
G Ccnb2 cyclin B2 JBrowse link 8 76,847,972 76,861,165 RGD:1624291
G Fzr1 fizzy and cell division cycle 20 related 1 JBrowse link 7 11,201,690 11,213,614 RGD:1624291
G Gpr3 G protein-coupled receptor 3 JBrowse link 5 151,394,118 151,397,634 RGD:1624291
G Grb14 growth factor receptor bound protein 14 JBrowse link 3 50,937,403 51,054,447 RGD:12793049
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:1624291
G Wee2 WEE1 homolog 2 JBrowse link 4 68,604,770 68,631,341 RGD:1624291
negative regulation of meiotic nuclear division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dmrt1 doublesex and mab-3 related transcription factor 1 JBrowse link 1 243,477,403 243,582,629 RGD:1624291
RGD:13792537
G Fbxo43 F-box protein 43 JBrowse link 7 74,925,091 74,938,796 RGD:1624291
RGD:13792537
G Fbxo5 F-box protein 5 JBrowse link 1 42,461,277 42,467,646 RGD:1624291
RGD:13792537
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:1624291
RGD:1600115
G Nanos2 nanos C2HC-type zinc finger 2 JBrowse link 1 79,894,450 79,895,910 RGD:1624291
RGD:1600115
G Osm oncostatin M JBrowse link 14 84,457,487 84,469,426 RGD:1624291
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha JBrowse link 10 97,940,705 97,959,199 RGD:633705
G Rps6ka2 ribosomal protein S6 kinase A2 JBrowse link 1 53,219,346 53,499,445 RGD:1624291
RGD:1600115
negative regulation of metaphase/anaphase transition of meiotic cell cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk1 leucine-rich repeat kinase 1 JBrowse link 1 127,166,866 127,301,053 RGD:13792537
G Mos MOS proto-oncogene, serine/threonine kinase JBrowse link 5 16,746,085 16,747,392 RGD:1600115
RGD:1624291
RGD:13792537
negative regulation of oocyte development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
RGD:1600115
G Wee2 WEE1 homolog 2 JBrowse link 4 68,604,770 68,631,341 RGD:1624291
negative regulation of oocyte maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpr3 G protein-coupled receptor 3 JBrowse link 5 151,394,118 151,397,634 RGD:1624291
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:1624291
RGD:1600115
G Npr2 natriuretic peptide receptor 2 JBrowse link 5 59,128,186 59,147,321 RGD:1624291
RGD:1600115
G Shb SH2 domain containing adaptor protein B JBrowse link 5 60,970,650 61,077,881 RGD:1624291
RGD:1600115
G Wee2 WEE1 homolog 2 JBrowse link 4 68,604,770 68,631,341 RGD:1624291
RGD:1600115
negative regulation of ovarian follicle development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amh anti-Mullerian hormone JBrowse link 7 11,775,155 11,777,503 RGD:2315646
G Hyal3 hyaluronidase 3 JBrowse link 8 116,336,512 116,342,147 RGD:1600115
RGD:1624291
negative regulation of ovulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpr149 G protein-coupled receptor 149 JBrowse link 2 152,838,836 152,912,027 RGD:1624291
RGD:1600115
negative regulation of penile erection term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
RGD:1600115
negative regulation of progesterone secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
negative regulation of prostatic bud formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
RGD:1600115
G Sulf1 sulfatase 1 JBrowse link 5 5,999,520 6,186,901 RGD:1600115
RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
negative regulation of sperm capacitation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lcn11 lipocalin 11 JBrowse link 3 2,935,396 2,938,883 RGD:1624291
negative regulation of trophoblast cell migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1c activin A receptor type 1C JBrowse link 3 44,272,859 44,342,501 RGD:1624291
RGD:1600115
G Arhgdib Rho GDP dissociation inhibitor beta JBrowse link 4 170,913,920 170,932,789 RGD:1624291
RGD:1600115
G Calr calreticulin JBrowse link 19 25,956,771 25,961,666 RGD:1624291
RGD:1600115
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
RGD:1600115
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:1624291
RGD:1600115
prevention of polyspermy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam24 ADAM metallopeptidase domain 24 JBrowse link 16 54,625,789 54,631,824 RGD:1600115
RGD:1624291
G Astl astacin like metalloendopeptidase JBrowse link 3 119,783,717 119,799,450 RGD:1624291
RGD:13792537
G Tpst2 tyrosylprotein sulfotransferase 2 JBrowse link 12 50,343,076 50,383,534 RGD:1624291
G Zp2 zona pellucida glycoprotein 2 JBrowse link 1 189,899,906 189,911,650 RGD:1600115
RGD:8554097
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17896
    negative regulation of biological process 5354
      negative regulation of reproductive process 73
        negative regulation of FtsZ-dependent cytokinesis 0
        negative regulation of amoeboid sperm motility 0
        negative regulation of cell differentiation involved in embryonic placenta development + 1
        negative regulation of conjugation with cellular fusion + 0
        negative regulation of embryo sac egg cell differentiation 0
        negative regulation of endosperm development 0
        negative regulation of epithelial cell proliferation involved in prostate gland development 7
        negative regulation of female pigmentation 0
        negative regulation of fertilization + 7
        negative regulation of flagellated sperm motility 5
        negative regulation of flower development + 0
        negative regulation of germ cell proliferation + 4
        negative regulation of gonad development + 9
        negative regulation of long-day photoperiodism, flowering 0
        negative regulation of male germ-line stem cell asymmetric division 0
        negative regulation of male mating behavior + 0
        negative regulation of male pigmentation 0
        negative regulation of maternal process involved in parturition 0
        negative regulation of mating type switching + 0
        negative regulation of meiotic cell cycle + 26
        negative regulation of nematode male tail tip morphogenesis 0
        negative regulation of oogenesis + 11
        negative regulation of oviposition 0
        negative regulation of ovulation 1
        negative regulation of penile erection 1
        negative regulation of placenta blood vessel development 0
        negative regulation of premature acrosome loss 0
        negative regulation of prostatic bud formation 4
        negative regulation of seed maturation + 0
        negative regulation of short-day photoperiodism, flowering 0
        negative regulation of signal transduction involved in conjugation with cellular fusion + 0
        negative regulation of sorocarp spore cell differentiation 0
        negative regulation of sperm capacitation 1
        negative regulation of spermatid nuclear differentiation 0
        negative regulation of spore-bearing organ development + 0
        negative regulation of trophoblast cell migration 5
        negative regulation of vitellogenesis 0
Path 2
Term Annotations click to browse term
  biological_process 17896
    biological regulation 12607
      regulation of biological process 11951
        negative regulation of biological process 5354
          negative regulation of reproductive process 73
            negative regulation of FtsZ-dependent cytokinesis 0
            negative regulation of amoeboid sperm motility 0
            negative regulation of cell differentiation involved in embryonic placenta development + 1
            negative regulation of conjugation with cellular fusion + 0
            negative regulation of embryo sac egg cell differentiation 0
            negative regulation of endosperm development 0
            negative regulation of epithelial cell proliferation involved in prostate gland development 7
            negative regulation of female pigmentation 0
            negative regulation of fertilization + 7
            negative regulation of flagellated sperm motility 5
            negative regulation of flower development + 0
            negative regulation of germ cell proliferation + 4
            negative regulation of gonad development + 9
            negative regulation of long-day photoperiodism, flowering 0
            negative regulation of male germ-line stem cell asymmetric division 0
            negative regulation of male mating behavior + 0
            negative regulation of male pigmentation 0
            negative regulation of maternal process involved in parturition 0
            negative regulation of mating type switching + 0
            negative regulation of meiotic cell cycle + 26
            negative regulation of nematode male tail tip morphogenesis 0
            negative regulation of oogenesis + 11
            negative regulation of oviposition 0
            negative regulation of ovulation 1
            negative regulation of penile erection 1
            negative regulation of placenta blood vessel development 0
            negative regulation of premature acrosome loss 0
            negative regulation of prostatic bud formation 4
            negative regulation of seed maturation + 0
            negative regulation of short-day photoperiodism, flowering 0
            negative regulation of signal transduction involved in conjugation with cellular fusion + 0
            negative regulation of sorocarp spore cell differentiation 0
            negative regulation of sperm capacitation 1
            negative regulation of spermatid nuclear differentiation 0
            negative regulation of spore-bearing organ development + 0
            negative regulation of trophoblast cell migration 5
            negative regulation of vitellogenesis 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.