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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of T-helper 17 cell differentiation
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Accession:GO:2000319 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation.
Synonyms:related_synonym: regulation of T-helper 17 cell development


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regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT ISO (MGI:MGI:3820359|PMID:19050256) RGD PMID:19050256 MGI:MGI:3820359 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 NOT ISO (MGI:MGI:3820359|PMID:19050256) RGD PMID:19050256 MGI:MGI:3820359 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474
JBrowse link
G Mir301a microRNA 301a ISO (MGI:MGI:5426073|PMID:22517757) RGD PMID:22517757 MGI:MGI:5426073 NCBI chr10:74,417,746...74,417,845
Ensembl chr10:74,417,746...74,417,845
JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 ISO (PMID:23169781) RGD PMID:23169781 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Il2 interleukin 2 ISO RNAcentral:URS000039ED8D_10090 (MGI:MGI:5634593|PMID:25642768) RGD PMID:25642768 MGI:MGI:5634593 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 ISO
IBA
(MGI:MGI:3817792|PMID:18792410)
PMID:21873635
RGD PMID:18792410, PMID:21873635 MGI:MGI:3817792, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 ISO (MGI:MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:MGI:6142401 NCBI chr13:78,723,028...78,794,663
Ensembl chr13:78,722,763...78,789,266
JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 ISO (MGI:MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:MGI:6142401 NCBI chr 3:21,621,976...21,676,789
Ensembl chr 3:21,623,041...21,670,014
JBrowse link
G Smad7 SMAD family member 7 IEA
ISO
GO_REF:0000107
(MGI:MGI:5634593|PMID:25642768)
Ensembl
RGD
PMID:25642768 GO_REF:0000107, MGI:MGI:5634593 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Tbx21 T-box transcription factor 21 ISO (MGI:MGI:4868293|PMID:21151104) RGD PMID:21151104 MGI:MGI:4868293 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B ISO MGI:MGI:3530739 (MGI:MGI:5450776|PMID:23034280) RGD PMID:23034280 MGI:MGI:5450776 NCBI chr 2:188,704,989...188,719,674
Ensembl chr 2:188,704,687...188,718,704
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A ISS
ISO
GO_REF:0000024
(MGI:MGI:6142401|PMID:25282160)
UniProt
RGD
PMID:25282160 GO_REF:0000024, MGI:MGI:6142401 NCBI chr 5:143,111,342...143,120,131
Ensembl chr 5:143,111,074...143,120,165
JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Loxl3 lysyl oxidase-like 3 ISO (MGI:MGI:5825383|PMID:28065600) RGD PMID:28065600 MGI:MGI:5825383 NCBI chr 4:113,866,782...113,883,713
Ensembl chr 4:113,866,804...113,883,477
JBrowse link
G Tbx21 T-box transcription factor 21 ISO (MGI:MGI:4868293|PMID:21151104) RGD PMID:21151104 MGI:MGI:4868293 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
G Tnfsf18 TNF superfamily member 18 ISO (MGI:MGI:5551556|PMID:24107315) RGD PMID:24107315 MGI:MGI:5551556 NCBI chr13:79,378,412...79,388,687
Ensembl chr13:79,378,733...79,388,498
JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Malt1 MALT1 paracaspase ISO (MGI:MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:MGI:6142401 NCBI chr18:61,108,712...61,162,446
Ensembl chr18:61,109,069...61,162,445
JBrowse link
G Mir326 microRNA 326 ISO (MGI:MGI:4436838|PMID:19838199) RGD PMID:19838199 MGI:MGI:4436838 NCBI chr 1:164,518,401...164,518,495
Ensembl chr 1:164,518,401...164,518,495
JBrowse link
G Nfkbid NFKB inhibitor delta ISO (MGI:MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:MGI:6142401 NCBI chr 1:88,883,816...88,892,543
Ensembl chr 1:88,885,937...88,892,615
JBrowse link
G Nfkbiz NFKB inhibitor zeta ISO (MGI:MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:MGI:6142401 NCBI chr11:47,243,342...47,271,487
Ensembl chr11:47,243,342...47,271,487
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO (MGI:MGI:5689221|PMID:26098997) RGD PMID:26098997 MGI:MGI:5689221 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23a interleukin 23 subunit alpha ISO
IBA
(MGI:MGI:3851279|PMID:19501566)
PMID:21873635
RGD PMID:19501566, PMID:21873635 MGI:MGI:3851279, RGD:13792537 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    immune system process 2837
      immune effector process 881
        regulation of immune effector process 427
          regulation of T-helper cell differentiation 38
            regulation of T-helper 17 cell differentiation 20
              negative regulation of T-helper 17 cell differentiation + 11
              positive regulation of T-helper 17 cell differentiation + 6
              regulation of T-helper 17 cell lineage commitment + 4
Path 2
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            immune system development 1073
              hematopoietic or lymphoid organ development 1008
                hemopoiesis 956
                  leukocyte differentiation 595
                    lymphocyte differentiation 407
                      T cell differentiation 289
                        T cell differentiation involved in immune response 75
                          alpha-beta T cell differentiation involved in immune response 67
                            CD4-positive, alpha-beta T cell differentiation involved in immune response 66
                              T-helper cell differentiation 64
                                regulation of T-helper cell differentiation 38
                                  regulation of T-helper 17 cell differentiation 20
                                    negative regulation of T-helper 17 cell differentiation + 11
                                    positive regulation of T-helper 17 cell differentiation + 6
                                    regulation of T-helper 17 cell lineage commitment + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.