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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of reactive oxygen species metabolic process
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Accession:GO:2000379 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.
Synonyms:exact_synonym: positive regulation of ROS metabolic process;   positive regulation of reactive oxygen species metabolism


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positive regulation of reactive oxygen species metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acod1 aconitate decarboxylase 1 JBrowse link 15 93,612,968 93,622,322 RGD:1624291
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:7244243
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:1624291
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:7829726
G Duoxa1 dual oxidase maturation factor 1 JBrowse link 3 114,241,057 114,251,720 RGD:1624291
G Eif5a eukaryotic translation initiation factor 5A JBrowse link 10 56,527,075 56,531,615 RGD:10395362
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:1600115
RGD:1624291
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:1624291
RGD:1600115
G Grb2 growth factor receptor bound protein 2 JBrowse link 10 104,193,953 104,263,071 RGD:1624291
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:8693628
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:1624291
RGD:1600115
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:1624291
G Nox1 NADPH oxidase 1 JBrowse link X 104,909,328 104,932,508 RGD:1581408
G Nox4 NADPH oxidase 4 JBrowse link 1 150,796,359 150,976,186 RGD:2324674
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 17 32,131,847 32,158,559 RGD:11073697
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1600115
RGD:1624291
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1624291
RGD:1600115
G Pid1 phosphotyrosine interaction domain containing 1 JBrowse link 9 91,667,748 91,683,468 RGD:1624291
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:6484217
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:1642626
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 15 34,470,796 34,479,741 RGD:1624291
G Rnf41 ring finger protein 41 JBrowse link 7 2,827,242 2,854,230 RGD:1624291
G Romo1 reactive oxygen species modulator 1 JBrowse link 3 151,688,213 151,689,813 RGD:1624291
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:2317161
RGD:1624291
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:1600115
RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
positive regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Duoxa1 dual oxidase maturation factor 1 JBrowse link 3 114,241,057 114,251,720 RGD:1624291
G Duoxa2 dual oxidase maturation factor 2 JBrowse link 3 114,236,718 114,240,086 RGD:1624291
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:12910740
G Mt-co2 mitochondrially encoded cytochrome c oxidase II JBrowse link MT 7,006 7,689 RGD:13506652
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:27095884
G Zfp13 zinc finger protein 13 JBrowse link 10 12,908,643 12,916,784 RGD:1624291
positive regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nnt nicotinamide nucleotide transhydrogenase JBrowse link 2 52,189,523 52,283,095 RGD:13513981
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:1624291
positive regulation of nitric oxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:8548892
G Agxt2 alanine-glyoxylate aminotransferase 2 JBrowse link 2 60,337,667 60,379,144 RGD:1624291
RGD:13792537
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:2313017
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:2313325
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Ass1 argininosuccinate synthase 1 JBrowse link 3 10,327,411 10,375,847 RGD:1624291
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Clec7a C-type lectin domain containing 7A JBrowse link 4 163,216,152 163,227,367 RGD:1624291
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:1624291
RGD:1600115
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:9586000
G Ddah1 dimethylarginine dimethylaminohydrolase 1 JBrowse link 2 251,634,368 251,766,009 RGD:727432
RGD:13792537
RGD:1624291
G Ddah2 dimethylarginine dimethylaminohydrolase 2 JBrowse link 20 5,049,260 5,052,573 RGD:13792537
G Dnm2 dynamin 2 JBrowse link 8 22,458,869 22,540,649 RGD:9685181
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:727463
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:1624291
RGD:1600115
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:1600239
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1624291
RGD:1600115
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:2306941
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1624291
RGD:1600115
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:1600239
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1641934
G Klf2 Kruppel-like factor 2 JBrowse link 16 19,223,087 19,225,037 RGD:1624291
G Klf4 Kruppel like factor 4 JBrowse link 5 72,283,311 72,287,669 RGD:1624291
G Klrk1 killer cell lectin like receptor K1 JBrowse link 4 163,392,652 163,403,735 RGD:1624291
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like JBrowse link 20 3,242,236 3,253,995 RGD:1624291
G LOC103692716 heat shock protein HSP 90-alpha JBrowse link 6 135,044,833 135,050,417 RGD:1600115
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:2304240
G Mir29b1 microRNA 29b-1 JBrowse link 4 58,344,310 58,344,390 RGD:13702880
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:1600115
RGD:1624291
RGD:13792525
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:10041012
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:1624291
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:5135054
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:10041069
G Ptx3 pentraxin 3 JBrowse link 2 158,097,843 158,103,653 RGD:1624291
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 JBrowse link 20 1,814,661 1,833,033 RGD:1600115
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:11535100
RGD:1624291
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:10042970
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:1624291
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:1624291
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1600115
RGD:1624291
G Tlr5 toll-like receptor 5 JBrowse link 13 101,364,784 101,385,764 RGD:1643119
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:2317115
G Ulbp1 UL16 binding protein 1 JBrowse link 1 1,181,301 1,200,526 RGD:1624291
positive regulation of nitric oxide metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:10448932
G Tmem106a transmembrane protein 106A JBrowse link 10 89,484,269 89,493,288 RGD:1600115
RGD:1624291
positive regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adgrb1 adhesion G protein-coupled receptor B1 JBrowse link 7 115,766,484 115,828,514 RGD:1624291
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Clcn3 chloride voltage-gated channel 3 JBrowse link 16 32,448,821 32,520,649 RGD:1624291
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:1624291
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:10402204
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:12910994
G Hdac4 histone deacetylase 4 JBrowse link 9 99,052,945 99,299,715 RGD:9681442
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:10402792
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:12910740
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:1624291
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 71,540,870 71,585,906 RGD:9590189
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
G Rab27a RAB27A, member RAS oncogene family JBrowse link 8 79,722,334 79,776,228 RGD:1624291
G Slc5a3 solute carrier family 5 member 3 JBrowse link 11 32,229,366 32,231,812 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:1624291
positive regulation of superoxide anion generation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:5129173
G Agtr1a angiotensin II receptor, type 1a JBrowse link 17 35,907,102 35,958,136 RGD:5129195
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Cd177 CD177 molecule JBrowse link 1 82,964,683 82,987,306 RGD:1624291
G Clec7a C-type lectin domain containing 7A JBrowse link 4 163,216,152 163,227,367 RGD:1624291
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:1624291
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:1600115
RGD:1624291
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:8693734
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:7204494
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
RGD:1600115
G Fpr2 formyl peptide receptor 2 JBrowse link 1 59,800,558 59,809,507 RGD:1624291
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:13507308
G Gnai3 G protein subunit alpha i3 JBrowse link 2 210,896,779 210,934,733 RGD:13507308
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:1624291
RGD:1600115
G Hvcn1 hydrogen voltage-gated channel 1 JBrowse link 12 39,822,814 39,851,093 RGD:14985214
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:4889403
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:1624291
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:1624291
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:1600115
RGD:1624291
G Olr1 oxidized low density lipoprotein receptor 1 JBrowse link 4 163,239,853 163,261,937 RGD:1624291
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1624291
RGD:1600115
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1624291
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tyrobp transmembrane immune signaling adaptor Tyrobp JBrowse link 1 88,875,370 88,879,305 RGD:1624291
positive regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:1624291
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:9590277
G Sirt3 sirtuin 3 JBrowse link 1 213,613,502 213,636,061 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      cellular metabolic process 10918
        positive regulation of cellular metabolic process 3567
          positive regulation of reactive oxygen species metabolic process 120
            positive regulation of hydrogen peroxide metabolic process + 8
            positive regulation of nitric oxide metabolic process + 52
            positive regulation of reactive oxygen species biosynthetic process + 66
            positive regulation of removal of superoxide radicals + 5
            positive regulation of superoxide anion generation 25
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        positive regulation of biological process 6625
          positive regulation of cellular process 6118
            positive regulation of cellular metabolic process 3567
              positive regulation of reactive oxygen species metabolic process 120
                positive regulation of hydrogen peroxide metabolic process + 8
                positive regulation of nitric oxide metabolic process + 52
                positive regulation of reactive oxygen species biosynthetic process + 66
                positive regulation of removal of superoxide radicals + 5
                positive regulation of superoxide anion generation 25
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.