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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of CD4-positive, alpha-beta T cell activation
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Accession:GO:2000514 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.


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regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd81 Cd81 molecule JBrowse link 1 216,237,663 216,253,460 RGD:1600115
RGD:1624291
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
negative regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 JBrowse link 1 64,241,742 64,256,646 RGD:1624291
G Twsg1 twisted gastrulation BMP signaling modulator 1 JBrowse link 9 113,699,151 113,732,601 RGD:1624291
negative regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd160 CD160 molecule JBrowse link 2 198,933,681 198,965,380 RGD:1624291
negative regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbfb core-binding factor subunit beta JBrowse link 19 37,127,508 37,171,075 RGD:1624291
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Runx1 RUNX family transcription factor 1 JBrowse link 11 32,765,147 33,003,061 RGD:1600115
RGD:1624291
G Runx3 RUNX family transcription factor 3 JBrowse link 5 153,507,093 153,531,137 RGD:1624291
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1600115
RGD:1624291
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:1624291
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
RGD:13792537
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 JBrowse link 1 64,241,742 64,256,646 RGD:1624291
G Twsg1 twisted gastrulation BMP signaling modulator 1 JBrowse link 9 113,699,151 113,732,601 RGD:1624291
G Vsir V-set immunoregulatory receptor JBrowse link 20 29,897,543 29,923,381 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
negative regulation of T-helper 1 cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:1624291
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
RGD:1600115
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
RGD:13792537
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Rc3h2 ring finger and CCCH-type domains 2 JBrowse link 3 21,621,976 21,676,789 RGD:1624291
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1600115
RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1600115
RGD:1624291
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Loxl3 lysyl oxidase-like 3 JBrowse link 4 113,866,782 113,883,713 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
G Tnfsf18 TNF superfamily member 18 JBrowse link 13 79,378,412 79,388,687 RGD:1624291
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:1624291
RGD:13792537
RGD:1600115
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Hlx H2.0-like homeobox JBrowse link 13 102,637,967 102,643,376 RGD:1624291
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:1624291
G Zfp35 zinc finger protein 35 JBrowse link 18 15,883,182 15,898,803 RGD:1624291
negative regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
positive regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd55 CD55 molecule (Cromer blood group) JBrowse link 13 47,125,156 47,153,557 RGD:1624291
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
positive regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd83 CD83 molecule JBrowse link 17 24,416,651 24,435,790 RGD:1624291
G Nckap1l NCK associated protein 1 like JBrowse link 7 145,068,239 145,113,507 RGD:1624291
RGD:1600115
G Sash3 SAM and SH3 domain containing 3 JBrowse link X 134,979,637 134,994,351 RGD:1624291
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:1600115
RGD:1624291
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1624291
positive regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd55 CD55 molecule (Cromer blood group) JBrowse link 13 47,125,156 47,153,557 RGD:1624291
G Cd81 Cd81 molecule JBrowse link 1 216,237,663 216,253,460 RGD:1600115
RGD:1624291
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
RGD:1600115
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Gimap5 GTPase, IMAP family member 5 JBrowse link 4 78,377,228 78,386,683 RGD:2303772
G Il2rg interleukin 2 receptor subunit gamma JBrowse link X 71,165,378 71,169,078 RGD:1624291
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:1624291
RGD:13792537
RGD:1600115
G Ccl19 C-C motif chemokine ligand 19 JBrowse link 5 58,181,025 58,182,969 RGD:1624291
G Hlx H2.0-like homeobox JBrowse link 13 102,637,967 102,643,376 RGD:1624291
G Ripk2 receptor-interacting serine-threonine kinase 2 JBrowse link 5 29,838,713 29,870,390 RGD:1624291
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:1624291
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Malt1 MALT1 paracaspase JBrowse link 18 61,108,712 61,162,446 RGD:1624291
G Mir326 microRNA 326 JBrowse link 1 164,518,401 164,518,495 RGD:1624291
G Nfkbid NFKB inhibitor delta JBrowse link 1 88,883,816 88,892,543 RGD:1624291
G Nfkbiz NFKB inhibitor zeta JBrowse link 11 47,243,342 47,271,487 RGD:1624291
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:1624291
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:1624291
RGD:13792537
positive regulation of T-helper 2 cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prkcq protein kinase C, theta JBrowse link 17 70,971,915 71,105,286 RGD:1600115
RGD:1624291
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:1624291
RGD:1600115
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:1624291
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:1624291
RGD:1600115
G Rara retinoic acid receptor, alpha JBrowse link 10 86,838,819 86,884,224 RGD:1624291
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
positive regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:1624291
G Shb SH2 domain containing adaptor protein B JBrowse link 5 60,970,650 61,077,881 RGD:1624291
regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
G Sh3rf1 SH3 domain containing ring finger 1 JBrowse link 16 32,062,425 32,227,526 RGD:1600115
RGD:1624291
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1624291
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il27 interleukin 27 JBrowse link 1 198,003,615 198,010,112 RGD:1624291
RGD:13792537
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl20 C-C motif chemokine ligand 20 JBrowse link 9 88,918,359 88,921,017 RGD:1624291
G Ccr6 C-C motif chemokine receptor 6 JBrowse link 1 53,063,380 53,087,519 RGD:1624291
G Mir301a microRNA 301a JBrowse link 10 74,417,746 74,417,845 RGD:1624291
regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il12rb2 interleukin 12 receptor subunit beta 2 JBrowse link 4 98,049,195 98,141,562 RGD:1331512

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    immune system process 2692
      regulation of immune system process 1473
        regulation of leukocyte activation 667
          regulation of lymphocyte activation 549
            regulation of T cell activation 322
              regulation of alpha-beta T cell activation 109
                regulation of CD4-positive, alpha-beta T cell activation 66
                  negative regulation of CD4-positive, alpha-beta T cell activation + 31
                  positive regulation of CD4-positive, alpha-beta T cell activation + 36
                  regulation of CD4-positive, alpha-beta T cell costimulation + 2
                  regulation of CD4-positive, alpha-beta T cell differentiation + 52
                  regulation of CD4-positive, alpha-beta T cell proliferation + 12
                  regulation of T-helper 1 cell activation + 1
                  regulation of T-helper 2 cell activation + 2
Path 2
Term Annotations click to browse term
  biological_process 19576
    biological regulation 13536
      regulation of biological process 12839
        regulation of cellular process 12332
          regulation of cell activation 711
            regulation of leukocyte activation 667
              regulation of lymphocyte activation 549
                regulation of T cell activation 322
                  regulation of alpha-beta T cell activation 109
                    regulation of CD4-positive, alpha-beta T cell activation 66
                      negative regulation of CD4-positive, alpha-beta T cell activation + 31
                      positive regulation of CD4-positive, alpha-beta T cell activation + 36
                      regulation of CD4-positive, alpha-beta T cell costimulation + 2
                      regulation of CD4-positive, alpha-beta T cell differentiation + 52
                      regulation of CD4-positive, alpha-beta T cell proliferation + 12
                      regulation of T-helper 1 cell activation + 1
                      regulation of T-helper 2 cell activation + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.