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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of CD4-positive, alpha-beta T cell activation
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Accession:GO:2000515 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.


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negative regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 JBrowse link 1 64,241,742 64,256,646 RGD:1624291
G Twsg1 twisted gastrulation BMP signaling modulator 1 JBrowse link 9 113,699,151 113,732,601 RGD:1624291
negative regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbfb core-binding factor subunit beta JBrowse link 19 37,127,508 37,171,075 RGD:1624291
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Runx1 RUNX family transcription factor 1 JBrowse link 11 32,765,147 33,003,061 RGD:1600115
RGD:1624291
G Runx3 RUNX family transcription factor 3 JBrowse link 5 153,507,093 153,531,137 RGD:1624291
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1600115
RGD:1624291
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:1624291
G Lgals5 lectin, galactose binding, soluble 5 JBrowse link 10 66,226,015 66,229,293 RGD:13792537
G Lgals7 galectin 7 JBrowse link 1 87,044,823 87,047,223 RGD:13792537
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
RGD:13792537
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 JBrowse link 1 64,241,742 64,256,646 RGD:1624291
G Twsg1 twisted gastrulation BMP signaling modulator 1 JBrowse link 9 113,699,151 113,732,601 RGD:1624291
G Vsir V-set immunoregulatory receptor JBrowse link 20 29,897,543 29,923,381 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
negative regulation of T-helper 1 cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:1624291
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
RGD:1600115
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
RGD:13792537
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Rc3h2 ring finger and CCCH-type domains 2 JBrowse link 3 21,621,976 21,676,789 RGD:1624291
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1600115
RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1600115
RGD:1624291
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Loxl3 lysyl oxidase-like 3 JBrowse link 4 113,866,782 113,883,713 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
G Tnfsf18 TNF superfamily member 18 JBrowse link 13 79,378,412 79,388,687 RGD:1624291
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:1624291
RGD:13792537
RGD:1600115
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Hlx H2.0-like homeobox JBrowse link 13 102,637,967 102,643,376 RGD:1624291
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:1624291
G Zfp35 zinc finger protein 35 JBrowse link 18 15,883,182 15,898,803 RGD:1624291
negative regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    immune system process 2798
      leukocyte activation 1045
        lymphocyte activation 862
          T cell activation 515
            alpha-beta T cell activation 171
              CD4-positive, alpha-beta T cell activation 106
                negative regulation of CD4-positive, alpha-beta T cell activation 33
                  negative regulation of CD4-positive, alpha-beta T cell differentiation + 23
                  negative regulation of CD4-positive, alpha-beta T cell proliferation 10
                  negative regulation of T-helper 1 cell activation 1
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          regulation of cell activation 745
            regulation of leukocyte activation 699
              regulation of lymphocyte activation 578
                regulation of T cell activation 332
                  regulation of alpha-beta T cell activation 111
                    negative regulation of alpha-beta T cell activation 44
                      negative regulation of CD4-positive, alpha-beta T cell activation 33
                        negative regulation of CD4-positive, alpha-beta T cell differentiation + 23
                        negative regulation of CD4-positive, alpha-beta T cell proliferation 10
                        negative regulation of T-helper 1 cell activation 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.