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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of interleukin-1-mediated signaling pathway
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Accession:GO:2000659 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of interleukin-1-mediated signaling pathway.
Synonyms:exact_synonym: regulation of IL-1-mediated signaling pathway;   regulation of interleukin-1-mediated signalling pathway
 related_synonym: regulation of IL-1 alpha-mediated signaling pathway;   regulation of IL-1 beta-mediated signaling pathway;   regulation of interleukin-1 alpha-mediated signaling pathway;   regulation of interleukin-1 beta-mediated signaling pathway


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regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vrk2 VRK serine/threonine kinase 2 ISO (PMID:18286207) RGD PMID:18286207 NCBI chr14:110,739,835...110,883,836
Ensembl chr14:110,739,226...110,883,803
JBrowse link
G Zbp1 Z-DNA binding protein 1 ISS
ISO
GO_REF:0000024
(MGI:6394181|PMID:31630209)
UniProt
RGD
PMID:31630209 GO_REF:0000024, MGI:6394181 NCBI chr 3:171,276,062...171,292,062
Ensembl chr 3:171,276,062...171,286,537
JBrowse link
negative regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1r2 interleukin 1 receptor type 2 IEA
ISO
GO_REF:0000107
PR:000045525 (MGI:5468848|PMID:23395675)
Ensembl
RGD
PMID:23395675 GO_REF:0000107, MGI:5468848 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Il1rn interleukin 1 receptor antagonist IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:2137200), (PMID:2139180)
Ensembl
RGD
PMID:2137200, PMID:2139180, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 ISO (MGI:5795829|PMID:11159963) RGD PMID:11159963 MGI:5795829 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Otud4 OTU deubiquitinase 4 ISO
IBA
(PMID:29395066)
(MGI:6120140|PMID:29395066)
PMID:21873635
RGD PMID:29395066, PMID:21873635 MGI:6120140, RGD:13792537 NCBI chr19:31,895,753...31,942,509
Ensembl chr19:31,899,087...31,942,180
JBrowse link
positive regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1r1 interleukin 1 receptor type 1 IEA
ISO
GO_REF:0000107
PR:000045524 (MGI:5468848|PMID:23395675)
Ensembl
RGD
PMID:23395675 GO_REF:0000107, MGI:5468848 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    regulation of biological process 13071
      regulation of response to stimulus 3982
        regulation of signal transduction 2934
          regulation of cytokine-mediated signaling pathway 113
            regulation of interleukin-1-mediated signaling pathway 7
              negative regulation of interleukin-1-mediated signaling pathway 4
              positive regulation of interleukin-1-mediated signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 20020
    response to stimulus 10580
      response to chemical 6337
        response to organic substance 3864
          response to cytokine 1132
            cellular response to cytokine stimulus 998
              cytokine-mediated signaling pathway 406
                regulation of cytokine-mediated signaling pathway 113
                  regulation of interleukin-1-mediated signaling pathway 7
                    negative regulation of interleukin-1-mediated signaling pathway 4
                    positive regulation of interleukin-1-mediated signaling pathway 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.