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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of stem cell differentiation
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Accession:GO:2000736 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of stem cell differentiation.


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regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III ISO MGI:MGI:3589287 (MGI:MGI:3528782|PMID:15713842) RGD PMID:15713842 MGI:MGI:3528782 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Kdm3a lysine demethylase 3A ISO
IEA
(MGI:MGI:3759699|PMID:17938240)
GO_REF:0000107
RGD
Ensembl
PMID:17938240 GO_REF:0000107, MGI:MGI:3759699 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Kdm4c lysine demethylase 4C ISO (MGI:MGI:3759699|PMID:17938240) RGD PMID:17938240 MGI:MGI:3759699 NCBI chr 5:90,800,139...91,012,662
Ensembl chr 5:90,800,082...91,012,659
JBrowse link
G Nsun2 NOP2/Sun RNA methyltransferase 2 ISO (MGI:MGI:5304206|PMID:22144916) RGD PMID:22144916 MGI:MGI:5304206 NCBI chr 1:36,295,650...36,319,906
Ensembl chr 1:36,295,650...36,319,966
JBrowse link
G Ociad1 OCIA domain containing 1 ISO
ISS
(MGI:MGI:5908327|PMID:23972987)
GO_REF:0000024
RGD
UniProt
PMID:23972987 GO_REF:0000024, MGI:MGI:5908327 NCBI chr14:37,458,023...37,475,485
Ensembl chr14:37,458,029...37,475,418
JBrowse link
G Prdm4 PR/SET domain 4 IMP PMID:23048031 ParkinsonsUK-UCL PMID:23048031 RGD:10054084 NCBI chr 7:23,959,932...23,986,535
Ensembl chr 7:23,960,378...23,985,525
JBrowse link
G Tead2 TEA domain transcription factor 2 ISO (MGI:MGI:5317256|PMID:21385842) RGD PMID:21385842 MGI:MGI:5317256 NCBI chr 1:101,213,782...101,230,483
Ensembl chr 1:101,213,788...101,230,477
JBrowse link
negative regulation of amniotic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rest RE1-silencing transcription factor ISO
ISS
(PMID:20942606)
GO_REF:0000024
RGD
UniProt
PMID:20942606 GO_REF:0000024 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prickle1 prickle planar cell polarity protein 1 IEA
ISO
GO_REF:0000107
(PMID:21199191)
Ensembl
RGD
PMID:21199191 GO_REF:0000107 NCBI chr 7:134,702,964...134,799,437
Ensembl chr 7:134,702,964...134,722,215
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
negative regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa9 heat shock protein family A (Hsp70) member 9 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5784980|PMID:21123823)
Ensembl
UniProt
RGD
PMID:21123823 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5784980 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G N4bp2l2 NEDD4 binding protein 2-like 2 ISO (PMID:19506020) RGD PMID:19506020 NCBI chr12:627,128...650,604
Ensembl chr12:628,488...650,376
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO (MGI:MGI:5476857|PMID:23434824) RGD PMID:23434824 MGI:MGI:5476857 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
negative regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir154 microRNA 154 ISO (MGI:MGI:5705446|PMID:25959411) RGD PMID:25959411 MGI:MGI:5705446 NCBI chr 6:133,888,586...133,888,669
Ensembl chr 6:133,888,586...133,888,669
JBrowse link
G Rest RE1-silencing transcription factor ISO (PMID:18570921) RGD PMID:18570921 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
negative regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnk cyclin K ISO (MGI:MGI:5467199|PMID:22547058) RGD PMID:22547058 MGI:MGI:5467199 NCBI chr 6:132,090,235...132,113,560
Ensembl chr 6:132,090,218...132,113,557
JBrowse link
G Cdk12 cyclin-dependent kinase 12 ISO (MGI:MGI:5467199|PMID:22547058) RGD PMID:22547058 MGI:MGI:5467199 NCBI chr10:86,157,186...86,210,657
Ensembl chr10:86,157,608...86,222,707
JBrowse link
G Cdk13 cyclin-dependent kinase 13 ISO (MGI:MGI:5467199|PMID:22547058) RGD PMID:22547058 MGI:MGI:5467199 NCBI chr17:49,833,194...49,922,932
Ensembl chr17:49,833,400...49,921,550
JBrowse link
G Esrrb estrogen-related receptor beta ISO
ISS
(MGI:MGI:5887187|PMID:26206133)
GO_REF:0000024
RGD
UniProt
PMID:26206133 GO_REF:0000024, MGI:MGI:5887187 NCBI chr 6:110,360,940...110,458,406
Ensembl chr 6:110,410,141...110,455,906
JBrowse link
G H1f8 H1.8 linker histone ISO
ISS
(MGI:MGI:5559660|PMID:22868987)
GO_REF:0000024
RGD
UniProt
PMID:22868987 GO_REF:0000024, MGI:MGI:5559660 NCBI chr 4:147,844,658...147,849,779
Ensembl chr 4:147,844,658...147,849,779
JBrowse link
G Hes1 hes family bHLH transcription factor 1 IEA
ISO
GO_REF:0000107
(PMID:19682396)
Ensembl
RGD
PMID:19682396 GO_REF:0000107 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hes5 hes family bHLH transcription factor 5 ISO
ISS
(PMID:19682396)
GO_REF:0000024
RGD
UniProt
PMID:19682396 GO_REF:0000024 NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5908336|PMID:21235343)
(PMID:21235343)
Ensembl
UniProt
RGD
PMID:21235343 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5908336 NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
JBrowse link
G Jag1 jagged canonical Notch ligand 1 IEA
ISO
GO_REF:0000107
(PMID:19682396)
Ensembl
RGD
PMID:19682396 GO_REF:0000107 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Lbh LBH regulator of WNT signaling pathway ISO (MGI:MGI:5634223|PMID:25655704) RGD PMID:25655704 MGI:MGI:5634223 NCBI chr 6:24,154,207...24,184,217
Ensembl chr 6:24,160,226...24,181,866
JBrowse link
G Mir125a microRNA 125a ISO MGI:MGI:1921298 (MGI:MGI:5465045|PMID:22751012) RGD PMID:22751012 MGI:MGI:5465045 NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 ISO (MGI:MGI:5467164|PMID:22977234) RGD PMID:22977234 MGI:MGI:5467164 NCBI chr 3:162,692,176...162,788,582
Ensembl chr 3:162,692,185...162,787,548
JBrowse link
G Nelfb negative elongation factor complex member B ISO (MGI:MGI:3845453|PMID:19340312) RGD PMID:19340312 MGI:MGI:3845453 NCBI chr 3:2,414,448...2,431,148
Ensembl chr 3:2,414,451...2,431,148
JBrowse link
G Notch1 notch receptor 1 ISO (PMID:19682396) RGD PMID:19682396 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO (MGI:MGI:5659778|PMID:25335925) RGD PMID:25335925 MGI:MGI:5659778 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Trim6 tripartite motif containing 6 ISO (MGI:MGI:5492022|PMID:22328504) RGD PMID:22328504 MGI:MGI:5492022 NCBI chr 1:169,410,084...169,423,305
Ensembl chr 1:169,410,115...169,423,283
JBrowse link
G Yap1 Yes1 associated transcriptional regulator ISO (MGI:MGI:4455217|PMID:20516196) RGD PMID:20516196 MGI:MGI:4455217 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 ISO (MGI:MGI:5500826|PMID:23748442) RGD PMID:23748442 MGI:MGI:5500826 NCBI chr 6:7,417,416...7,423,447
Ensembl chr 6:7,417,425...7,421,456
JBrowse link
positive regulation of cardioblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx36 DEAH-box helicase 36 ISS
ISO
GO_REF:0000024
(MGI:MGI:6201954|PMID:26489465)
UniProt
RGD
PMID:26489465 GO_REF:0000024, MGI:MGI:6201954 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Gata4 GATA binding protein 4 ISO (PMID:16137232) RGD PMID:16137232 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gata6 GATA binding protein 6 ISO
IEA
(PMID:16137232)
GO_REF:0000107
RGD
Ensembl
PMID:16137232 GO_REF:0000107 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Nkx2-5 NK2 homeobox 5 ISO
IEA
(MGI:MGI:3784761|PMID:11889119)
GO_REF:0000107
RGD
Ensembl
PMID:11889119 GO_REF:0000107, MGI:MGI:3784761 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Tbx5 T-box transcription factor 5 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:11431700)
Ensembl
UniProt
RGD
PMID:11431700 GO_REF:0000024, GO_REF:0000107 NCBI chr12:42,059,688...42,148,226
Ensembl chr12:42,097,626...42,148,146
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO
ISS
(PMID:15896309)
GO_REF:0000024
RGD
UniProt
PMID:15896309 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
positive regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc1 forkhead box C1 ISO (MGI:MGI:5569870|PMID:24590069) RGD PMID:24590069 MGI:MGI:5569870 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484
JBrowse link
positive regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ltbp3 latent transforming growth factor beta binding protein 3 ISO (PMID:18672106) RGD PMID:18672106 NCBI chr 1:221,099,155...221,116,096
Ensembl chr 1:221,099,998...221,116,096
JBrowse link
G Sox5 SRY-box transcription factor 5 ISO (PMID:21401405) RGD PMID:21401405 NCBI chr 4:178,062,267...179,031,991
Ensembl chr 4:178,066,165...178,441,547
JBrowse link
G Sox6 SRY-box transcription factor 6 ISO (PMID:21401405) RGD PMID:21401405 NCBI chr 1:185,631,702...186,186,192
Ensembl chr 1:185,673,177...186,182,829
JBrowse link
G Sox9 SRY-box transcription factor 9 ISO
ISS
(PMID:21401405)
GO_REF:0000024
RGD
UniProt
PMID:21401405 GO_REF:0000024 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
positive regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3b glycogen synthase kinase 3 beta ISO (MGI:MGI:5319061|PMID:22064483) RGD PMID:22064483 MGI:MGI:5319061 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hoxb4 homeo box B4 ISO (PMID:18932205) RGD PMID:18932205 NCBI chr10:84,167,331...84,169,913
Ensembl chr10:84,167,331...84,169,907
JBrowse link
G Mir100 microRNA 100 ISO (MGI:MGI:4822296|PMID:20439489) RGD PMID:20439489 MGI:MGI:4822296 NCBI chr 8:45,746,948...45,747,027
Ensembl chr 8:45,746,948...45,747,027
JBrowse link
G Mir137 microRNA 137 ISO (MGI:MGI:4822296|PMID:20439489) RGD PMID:20439489 MGI:MGI:4822296 NCBI chr 2:221,658,106...221,658,207
Ensembl chr 2:221,658,106...221,658,207
JBrowse link
G Mir34a microRNA 34a ISO (MGI:MGI:4822296|PMID:20439489) RGD PMID:20439489 MGI:MGI:4822296 NCBI chr 5:167,092,491...167,092,592
Ensembl chr 5:167,092,491...167,092,592
JBrowse link
G Nudt21 nudix hydrolase 21 ISS
ISO
GO_REF:0000024
(MGI:MGI:6110185|PMID:29249356)
UniProt
RGD
PMID:29249356 GO_REF:0000024, MGI:MGI:6110185 NCBI chr19:11,451,366...11,470,637
Ensembl chr19:11,450,760...11,467,644
JBrowse link
G Ptn pleiotrophin ISS
ISO
GO_REF:0000024
(MGI:MGI:3045656|PMID:15121180)
UniProt
RGD
PMID:15121180 GO_REF:0000024, MGI:MGI:3045656 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
JBrowse link
G Pwp1 PWP1 homolog, endonuclein ISO (MGI:MGI:5659778|PMID:25335925) RGD PMID:25335925 MGI:MGI:5659778 NCBI chr 7:23,988,776...24,004,774
Ensembl chr 7:23,988,776...24,004,774
JBrowse link
G Rbm24 RNA binding motif protein 24 ISO (PMID:26990106) RGD PMID:26990106 NCBI chr17:18,671,037...18,682,876
Ensembl chr17:18,671,044...18,682,876
JBrowse link
G Sp7 Sp7 transcription factor ISO (PMID:18932205) RGD PMID:18932205 NCBI chr 7:143,957,316...143,967,488
Ensembl chr 7:143,958,858...143,967,484
JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 ISO
IBA
IEA
(MGI:MGI:5440097|PMID:23070813)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:23070813, PMID:21873635 GO_REF:0000107, MGI:MGI:5440097, RGD:13792537 NCBI chr 4:98,341,187...98,342,887
Ensembl chr 4:98,341,188...98,342,887
JBrowse link
G Vsir V-set immunoregulatory receptor ISO MGI:MGI:2676809 (MGI:MGI:5465045|PMID:22751012) RGD PMID:22751012 MGI:MGI:5465045 NCBI chr20:29,897,543...29,923,381
Ensembl chr20:29,897,594...29,919,998
JBrowse link
regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk6 cyclin-dependent kinase 6 ISO MGI:MGI:3053975 (MGI:MGI:5636128|PMID:25342715) RGD PMID:25342715 MGI:MGI:5636128 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 ISO
ISS
(MGI:MGI:5487705|PMID:23403623)
GO_REF:0000024
RGD
UniProt
PMID:23403623 GO_REF:0000024, MGI:MGI:5487705 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO (MGI:MGI:6414739|PMID:32103174) RGD PMID:32103174 MGI:MGI:6414739 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Pus7 pseudouridine synthase 7 ISO (PMID:29628141) RGD PMID:29628141 NCBI chr 4:7,889,727...7,931,357
Ensembl chr 4:7,889,869...7,930,706
JBrowse link
G Setd1a SET domain containing 1A, histone lysine methyltransferase ISO (PMID:27141965) RGD PMID:27141965 NCBI chr 1:199,222,584...199,247,993
Ensembl chr 1:199,225,100...199,247,988
JBrowse link
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 ISO (MGI:MGI:6316688|PMID:30065315), (MGI:MGI:6317061|PMID:30150673) RGD PMID:30065315, PMID:30150673 MGI:MGI:6316688, MGI:MGI:6317061 NCBI chr 5:150,364,490...150,390,173
Ensembl chr 5:150,365,101...150,390,099
JBrowse link
regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfra platelet derived growth factor receptor alpha ISO
IEA
ISS
(PMID:21596750)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:21596750 GO_REF:0000024, GO_REF:0000107 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
regulation of neural crest cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A NOT ISO (MGI:MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:MGI:3040576 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A NOT ISO (MGI:MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:MGI:3040576 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      regulation of developmental process 2644
        regulation of cell differentiation 1683
          regulation of stem cell differentiation 63
            negative regulation of stem cell differentiation + 25
            positive regulation of stem cell differentiation + 23
            regulation of cardioblast differentiation + 8
            regulation of hematopoietic stem cell differentiation + 10
            regulation of mesenchymal stem cell differentiation + 7
            regulation of neural crest cell differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cellular developmental process 4459
        cell differentiation 4363
          regulation of cell differentiation 1683
            regulation of stem cell differentiation 63
              negative regulation of stem cell differentiation + 25
              positive regulation of stem cell differentiation + 23
              regulation of cardioblast differentiation + 8
              regulation of hematopoietic stem cell differentiation + 10
              regulation of mesenchymal stem cell differentiation + 7
              regulation of neural crest cell differentiation + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.