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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cellular senescence
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Accession:GO:2000773 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence.


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negative regulation of cellular senescence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO MGI:MGI:104738 (MGI:MGI:5449665|PMID:22729085) RGD PMID:22729085 MGI:MGI:5449665 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
JBrowse link
G Akt3 AKT serine/threonine kinase 3 ISO
IEA
(PMID:25323119)
GO_REF:0000107
RGD
Ensembl
PMID:25323119 GO_REF:0000107 NCBI chr13:95,076,308...95,348,913
Ensembl chr13:95,081,390...95,348,913
JBrowse link
G Bcl2l12 BCL2 like 12 ISO (MGI:MGI:4834958|PMID:20837658) RGD PMID:20837658 MGI:MGI:4834958 NCBI chr 1:100,984,550...100,993,269
Ensembl chr 1:100,984,550...100,993,269
JBrowse link
G Bcl6 BCL6, transcription repressor ISO MGI:MGI:2158436 (MGI:MGI:5469797|PMID:23209284) RGD PMID:23209284 MGI:MGI:5469797 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Cdk6 cyclin-dependent kinase 6 ISO (PMID:17420273) RGD PMID:17420273 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Fbxo5 F-box protein 5 ISO (PMID:17875940) RGD PMID:17875940 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
G Hmga2 high mobility group AT-hook 2 ISO (MGI:MGI:5582375|PMID:23072816) RGD PMID:23072816 MGI:MGI:5582375 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G LOC100912427 nuclease-sensitive element-binding protein 1-like ISO (MGI:MGI:6158172|PMID:29712925) RGD PMID:29712925 MGI:MGI:6158172 NCBI chr 1:186,635,408...186,641,503
Ensembl chr 1:186,640,425...186,641,393
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO (PMID:28640956) RGD PMID:28640956 NCBI chr10:94,280,703...94,349,372
Ensembl chr10:94,280,703...94,349,368
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IDA RGD PMID:28125705 RGD:13781884 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Plk2 polo-like kinase 2 ISO (MGI:MGI:6120300|PMID:27908889) RGD PMID:27908889 MGI:MGI:6120300 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit IMP RGD PMID:22981234 RGD:8696027 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 ISO (PMID:28595801) RGD PMID:28595801 NCBI chr 3:153,263,692...153,321,351
Ensembl chr 3:153,263,692...153,321,352
JBrowse link
G Sirt1 sirtuin 1 ISO
IEA
(PMID:20203304), (PMID:20424141)
GO_REF:0000107
RGD
Ensembl
PMID:20203304, PMID:20424141 GO_REF:0000107 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc30a10 solute carrier family 30, member 10 ISO (PMID:22427991) RGD PMID:22427991 NCBI chr13:103,396,295...103,406,759
Ensembl chr13:103,396,314...103,410,363
JBrowse link
G Terf2 telomeric repeat binding factor 2 ISO (PMID:11927518) RGD PMID:11927518 NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893
JBrowse link
G Tert telomerase reverse transcriptase ISO (PMID:11313459), (PMID:11927518) RGD PMID:11313459, PMID:11927518 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tp63 tumor protein p63 ISO (PMID:19451233) RGD PMID:19451233 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:17690110) RGD PMID:17690110 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
G Ybx1 Y box binding protein 1 ISS
IEA
GO_REF:0000024
GO_REF:0000107
UniProt
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 5:138,319,754...138,336,721
Ensembl chr 5:138,319,762...138,336,475
JBrowse link
G Zkscan3 zinc finger with KRAB and SCAN domains 3 ISO (PMID:23434374) RGD PMID:23434374 NCBI chr17:45,247,724...45,263,422
Ensembl chr17:45,247,776...45,263,418
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    negative regulation of biological process 5698
      negative regulation of response to stimulus 1663
        negative regulation of cellular senescence 21
Path 2
Term Annotations click to browse term
  biological_process 20015
    biological regulation 13760
      regulation of biological process 13073
        regulation of response to stimulus 4099
          regulation of response to stress 1402
            regulation of cellular response to stress 728
              regulation of cellular senescence 44
                negative regulation of cellular senescence 21
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.