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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of double-strand break repair
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Accession:GO:2000779 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of double-strand break repair.


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regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dek DEK proto-oncogene ISO
IBA
(PMID:21653549)
PMID:21873635
RGD PMID:21653549, PMID:21873635 RGD:13792537 NCBI chr17:17,965,872...17,987,836
Ensembl chr17:17,965,881...17,987,834
JBrowse link
G Pml PML nuclear body scaffold ISO (PMID:21639834) RGD PMID:21639834 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Trip12 thyroid hormone receptor interactor 12 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:92,305,059...92,435,388
Ensembl chr 9:92,305,051...92,435,365
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:76,789,110...76,835,517
NCBI chr 7:76,839,661...76,907,441
Ensembl chr 7:76,789,531...76,853,840
JBrowse link
negative regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 ISO
IBA
ISS
(PMID:20725033)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:20725033, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:222,451,674...222,459,952
Ensembl chr 1:222,451,674...222,459,952
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:127,282,445...127,301,086
Ensembl chr 6:127,282,466...127,301,083
JBrowse link
G Rnf169 ring finger protein 169 ISO (PMID:22492721), (PMID:22733822), (PMID:22742833) RGD PMID:22492721, PMID:22733822, PMID:22742833 NCBI chr 1:164,917,069...164,978,061
Ensembl chr 1:164,922,080...164,977,633
JBrowse link
G Trip12 thyroid hormone receptor interactor 12 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:22884692)
Ensembl
UniProt
RGD
PMID:22884692 GO_REF:0000024, GO_REF:0000107 NCBI chr 9:92,305,059...92,435,388
Ensembl chr 9:92,305,051...92,435,365
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:17690110) RGD PMID:17690110 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:22884692)
Ensembl
UniProt
RGD
PMID:22884692 GO_REF:0000024, GO_REF:0000107 NCBI chr 7:76,789,110...76,835,517
NCBI chr 7:76,839,661...76,907,441
Ensembl chr 7:76,789,531...76,853,840
JBrowse link
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase ISO
IBA
(PMID:30356214)
PMID:21873635
(MGI:MGI:6241455|PMID:30356214)
RGD PMID:30356214, PMID:21873635 MGI:MGI:6241455, RGD:13792537 NCBI chr 8:85,789,515...85,804,008
Ensembl chr 8:85,789,763...85,803,433
JBrowse link
G Fancb FA complementation group B ISO
IBA
MGI:MGI:2156841 (MGI:MGI:5648586|PMID:25520194)
PMID:21873635
RGD PMID:25520194, PMID:21873635 MGI:MGI:5648586, RGD:13792537 NCBI chr  X:31,124,018...31,140,790
Ensembl chr  X:31,124,018...31,140,711
JBrowse link
G Fbh1 F-box DNA helicase 1 ISO (PMID:19736316)
(MGI:MGI:5566975|PMID:24108124)
RGD PMID:19736316, PMID:24108124 MGI:MGI:5566975 NCBI chr17:70,399,093...70,437,151
Ensembl chr17:70,399,049...70,437,144
JBrowse link
G Helb DNA helicase B ISO
IBA
(PMID:26774285)
PMID:21873635
(MGI:MGI:5766842|PMID:26774285)
RGD PMID:26774285, PMID:21873635 MGI:MGI:5766842, RGD:13792537 NCBI chr 7:64,860,641...64,888,146
Ensembl chr 7:64,860,666...64,887,448
JBrowse link
G Klhl15 kelch-like family member 15 ISO (PMID:27561354) RGD PMID:27561354 NCBI chr  X:63,342,277...63,390,915
Ensembl chr  X:63,343,546...63,389,989
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:164,943,183...164,956,255
Ensembl chr 5:164,950,917...164,956,255
JBrowse link
G Parpbp PARP1 binding protein ISO
IBA
IEA
ISS
(PMID:22153967)
PMID:21873635
GO_REF:0000002
GO_REF:0000024
RGD
InterPro
UniProt
PMID:22153967, PMID:21873635 GO_REF:0000002, GO_REF:0000024, RGD:13792537 NCBI chr 7:28,654,707...28,724,412
Ensembl chr 7:28,654,707...28,715,224
JBrowse link
G Polq DNA polymerase theta ISO (PMID:25642963)
(MGI:MGI:5621198|PMID:25642960)
RGD PMID:25642960, PMID:25642963 MGI:MGI:5621198 NCBI chr11:66,585,860...66,695,369
Ensembl chr11:66,585,881...66,695,353
JBrowse link
G Radx RPA1 related single stranded DNA binding protein, X-linked ISO
ISS
(PMID:28735897)
GO_REF:0000024
RGD
UniProt
PMID:28735897 GO_REF:0000024 NCBI chr  X:110,670,037...110,782,420
Ensembl chr  X:110,670,119...110,782,284
JBrowse link
G Recql5 RecQ like helicase 5 ISO MGI:MGI:2448558 (MGI:MGI:5648586|PMID:25520194) RGD PMID:25520194 MGI:MGI:5648586 NCBI chr10:104,443,735...104,482,889
Ensembl chr10:104,443,736...104,482,838
JBrowse link
G Rif1 replication timing regulatory factor 1 ISO (PMID:23333306)
(MGI:MGI:5468037|PMID:23306437), (MGI:MGI:5476381|PMID:23333305)
RGD PMID:23306437, PMID:23333305, PMID:23333306 MGI:MGI:5468037, MGI:MGI:5476381 NCBI chr 3:37,599,540...37,648,818
Ensembl chr 3:37,599,728...37,647,631
JBrowse link
G Rmi2 RecQ mediated genome instability 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:4,904,458...4,910,339
Ensembl chr10:4,905,210...4,910,305
JBrowse link
G Shld1 shieldin complex subunit 1 ISO
IBA
(PMID:29656893)
PMID:21873635
RGD PMID:29656893, PMID:21873635 RGD:13792537 NCBI chr 3:125,318,682...125,396,705
Ensembl chr 3:125,320,680...125,396,821
JBrowse link
G Shld2 shieldin complex subunit 2 ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:10,570,307...10,661,528
Ensembl chr16:10,570,314...10,661,528
JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 ISO (PMID:25294876) RGD PMID:25294876 NCBI chr 9:119,675,750...119,818,620
Ensembl chr 9:119,676,628...119,818,310
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 ISO (PMID:23333306), (PMID:23345425)
(MGI:MGI:5476381|PMID:23333305), (MGI:MGI:5887194|PMID:20362325)
RGD PMID:20362325, PMID:23333305, PMID:23333306, PMID:23345425 MGI:MGI:5476381, MGI:MGI:5887194 NCBI chr 3:113,160,030...113,259,701
Ensembl chr 3:113,160,000...113,231,790
JBrowse link
G Ubqln4 ubiquilin 4 ISO (PMID:30612738) RGD PMID:30612738 NCBI chr 2:187,915,701...187,931,035
Ensembl chr 2:187,915,751...187,931,035
JBrowse link
negative regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aunip aurora kinase A and ninein interacting protein ISO
ISS
(PMID:29042561)
GO_REF:0000024
RGD
UniProt
PMID:29042561 GO_REF:0000024 NCBI chr 5:152,721,799...152,734,577
Ensembl chr 5:152,721,940...152,734,572
JBrowse link
G Cyren cell cycle regulator of NHEJ ISO
ISS
(PMID:28959974)
GO_REF:0000024
RGD
UniProt
PMID:28959974 GO_REF:0000024 NCBI chr 4:62,391,770...62,397,162
Ensembl chr 4:62,391,770...62,396,035
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Hmga2 high mobility group AT-hook 2 ISO
ISS
(PMID:19549901)
GO_REF:0000024
RGD
UniProt
PMID:19549901 GO_REF:0000024 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Hsf1 heat shock transcription factor 1 ISO (PMID:26359349) RGD PMID:26359349 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Nudt16l1 nudix hydrolase 16 like 1 ISO (PMID:28241136) RGD PMID:28241136 NCBI chr10:10,829,866...10,831,782
Ensembl chr10:10,829,867...10,831,782
JBrowse link
negative regulation of double-strand break repair via single-strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ogg1 8-oxoguanine DNA glycosylase ISO (PMID:19506022) RGD PMID:19506022 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
positive regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx11 DEAD/H-box helicase 11 ISO (PMID:23797032) RGD PMID:23797032 NCBI chr 9:114,113,642...114,133,908
Ensembl chr 9:114,111,580...114,132,492
JBrowse link
G Fmn2 formin 2 ISO (PMID:26287480) RGD PMID:26287480 NCBI chr13:92,569,256...92,887,302 JBrowse link
G Foxm1 forkhead box M1 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(MGI:MGI:3698692|PMID:17101782)
(PMID:17101782)
Ensembl
RGD
PMID:17101782, PMID:21873635 GO_REF:0000107, MGI:MGI:3698692, RGD:13792537 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305
JBrowse link
G LOC100910636 zinc finger CW-type PWWP domain protein 1-like ISO (MGI:MGI:6358520|PMID:31453335) RGD PMID:31453335 MGI:MGI:6358520 NCBI chr12:21,690,074...21,720,186
Ensembl chr12:21,689,095...21,720,094
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO (PMID:24147153) RGD PMID:24147153 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Nudt16 nudix hydrolase 16 ISO (PMID:20385596) RGD PMID:20385596 NCBI chr 8:113,673,069...113,675,124
Ensembl chr 8:113,672,758...113,675,128
JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 2:4,095,126...4,195,819
Ensembl chr 2:4,095,129...4,195,810
JBrowse link
G Slf2 SMC5-SMC6 complex localization factor 2 ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 1:264,670,836...264,733,465
Ensembl chr 1:264,670,841...264,733,306
JBrowse link
G Spidr scaffold protein involved in DNA repair ISO (PMID:23509288) RGD PMID:23509288 NCBI chr11:89,009,931...89,260,361
Ensembl chr11:89,009,931...89,260,297
JBrowse link
G Spire1 spire-type actin nucleation factor 1 ISO (PMID:26287480) RGD PMID:26287480 NCBI chr18:63,226,557...63,357,420
Ensembl chr18:63,226,557...63,357,298
JBrowse link
G Spire2 spire-type actin nucleation factor 2 ISO (PMID:26287480) RGD PMID:26287480 NCBI chr19:56,136,904...56,175,500
Ensembl chr19:56,136,904...56,175,500
JBrowse link
G Timeless timeless circadian regulator ISO
ISS
(PMID:23797032)
GO_REF:0000024
RGD
UniProt
PMID:23797032 GO_REF:0000024 NCBI chr 7:2,643,288...2,667,329
Ensembl chr 7:2,643,288...2,667,628
JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 ISS
ISO
GO_REF:0000024
(PMID:27715493)
UniProt
RGD
PMID:27715493 GO_REF:0000024 NCBI chr10:56,169,024...56,185,800
Ensembl chr10:56,169,025...56,185,857
JBrowse link
G Zcwpw1 zinc finger CW-type and PWWP domain containing 1 ISO (MGI:MGI:6358520|PMID:31453335) RGD PMID:31453335 MGI:MGI:6358520 NCBI chr12:21,418,874...21,450,617 JBrowse link
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr2 actin related protein 2 ISS
ISO
GO_REF:0000024
(PMID:29925947)
UniProt
RGD
PMID:29925947 GO_REF:0000024 NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649
JBrowse link
G Arid2 AT-rich interaction domain 2 ISO (PMID:28381560) RGD PMID:28381560 NCBI chr 7:137,680,564...137,798,329
Ensembl chr 7:137,680,530...137,795,655
JBrowse link
G Blm BLM RecQ like helicase ISO MGI:MGI:2448558 (MGI:MGI:5648586|PMID:25520194) RGD PMID:25520194 MGI:MGI:5648586 NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Fancb FA complementation group B ISO
IBA
MGI:MGI:1328362 (MGI:MGI:5648586|PMID:25520194)
PMID:21873635
RGD PMID:25520194, PMID:21873635 MGI:MGI:5648586, RGD:13792537 NCBI chr  X:31,124,018...31,140,790
Ensembl chr  X:31,124,018...31,140,711
JBrowse link
G Fus FUS RNA binding protein ISO (PMID:10567410) RGD PMID:10567410 NCBI chr 1:199,412,805...199,426,705
Ensembl chr 1:199,412,834...199,426,702
JBrowse link
G Mms19 MMS19 homolog, cytosolic iron-sulfur assembly component ISO (PMID:29225034) RGD PMID:29225034 NCBI chr 1:261,191,646...261,229,070
Ensembl chr 1:261,191,646...261,229,046
JBrowse link
G Mrnip MRN complex interacting protein ISO (PMID:27568553) RGD PMID:27568553 NCBI chr10:35,680,687...35,704,685
Ensembl chr10:35,680,658...35,704,776
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISS
ISO
GO_REF:0000024
(PMID:26344098), (PMID:30356214)
UniProt
RGD
PMID:26344098, PMID:30356214 GO_REF:0000024 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Timeless timeless circadian regulator ISS
ISO
IEA
GO_REF:0000024
(PMID:26344098), (PMID:30356214)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:26344098, PMID:30356214 GO_REF:0000024, GO_REF:0000107 NCBI chr 7:2,643,288...2,667,329
Ensembl chr 7:2,643,288...2,667,628
JBrowse link
G Was WASP actin nucleation promoting factor ISO (PMID:29925947) RGD PMID:29925947 NCBI chr  X:15,155,246...15,164,099
Ensembl chr  X:15,155,230...15,164,105
JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 ISS
ISO
GO_REF:0000024
(PMID:25512560)
UniProt
RGD
PMID:25512560 GO_REF:0000024 NCBI chr10:56,169,024...56,185,800
Ensembl chr10:56,169,025...56,185,857
JBrowse link
positive regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dtx3l deltex E3 ubiquitin ligase 3L ISO (PMID:28525742) RGD PMID:28525742 NCBI chr11:67,758,093...67,767,623
NCBI chr11:67,768,542...67,772,428
Ensembl chr11:67,757,928...67,767,622
JBrowse link
G Fh fumarate hydratase ISS
ISO
GO_REF:0000024
(PMID:26237645)
UniProt
RGD
PMID:26237645 GO_REF:0000024 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
JBrowse link
G Kdm4d lysine demethylase 4D ISO (PMID:24550317) RGD PMID:24550317 NCBI chr 8:12,968,192...12,993,651
Ensembl chr 8:13,511,805...13,513,337
JBrowse link
G Kmt5b lysine methyltransferase 5B ISO
ISS
(PMID:28114273)
GO_REF:0000024
RGD
UniProt
PMID:28114273 GO_REF:0000024 NCBI chr 1:219,000,844...219,050,211
Ensembl chr 1:219,000,844...219,050,211
JBrowse link
G Kmt5c lysine methyltransferase 5C ISO
ISS
(PMID:28114273)
GO_REF:0000024
RGD
UniProt
PMID:28114273 GO_REF:0000024 NCBI chr 1:72,666,662...72,674,271
Ensembl chr 1:72,666,665...72,674,271
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:164,943,183...164,956,255
Ensembl chr 5:164,950,917...164,956,255
JBrowse link
G Parp3 poly (ADP-ribose) polymerase family, member 3 ISO (PMID:24598253) RGD PMID:24598253 NCBI chr 8:115,173,440...115,179,543
Ensembl chr 8:115,173,453...115,179,191
JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 ISO (PMID:28525742) RGD PMID:28525742 NCBI chr11:67,724,071...67,758,027
Ensembl chr11:67,724,076...67,756,799
JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase ISO (PMID:12032095) RGD PMID:12032095 NCBI chr 1:100,853,475...100,859,202
Ensembl chr 1:100,853,902...100,859,084
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO (PMID:26237645) RGD PMID:26237645 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Rif1 replication timing regulatory factor 1 ISO (PMID:28241136)
(MGI:MGI:5468037|PMID:23306437), (MGI:MGI:5476381|PMID:23333305)
RGD PMID:23306437, PMID:23333305, PMID:28241136 MGI:MGI:5468037, MGI:MGI:5476381 NCBI chr 3:37,599,540...37,648,818
Ensembl chr 3:37,599,728...37,647,631
JBrowse link
G Setmar SET domain and mariner transposase fusion gene ISO (PMID:20620605), (PMID:21491884) RGD PMID:20620605, PMID:21491884 NCBI chr 4:140,092,346...140,104,495
Ensembl chr 4:140,092,352...140,105,316
JBrowse link
G Shld1 shieldin complex subunit 1 ISO
IBA
(PMID:29656893)
PMID:21873635
RGD PMID:29656893, PMID:21873635 RGD:13792537 NCBI chr 3:125,318,682...125,396,705
Ensembl chr 3:125,320,680...125,396,821
JBrowse link
G Shld2 shieldin complex subunit 2 ISO (PMID:29656893), (PMID:29789392) RGD PMID:29656893, PMID:29789392 NCBI chr16:10,570,307...10,661,528
Ensembl chr16:10,570,314...10,661,528
JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 ISO (PMID:25294876) RGD PMID:25294876 NCBI chr 9:119,675,750...119,818,620
Ensembl chr 9:119,676,628...119,818,310
JBrowse link
G Top2b DNA topoisomerase II beta IMP RGD PMID:22019940 RGD:13432143 NCBI chr15:10,262,972...10,319,741
Ensembl chr15:10,262,651...10,320,233
JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 ISS
ISO
GO_REF:0000024
(PMID:25512560)
UniProt
RGD
PMID:25512560 GO_REF:0000024 NCBI chr10:56,169,024...56,185,800
Ensembl chr10:56,169,025...56,185,857
JBrowse link
regulation of DNA double-strand break processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Helb DNA helicase B ISO (PMID:26774285)
(MGI:MGI:5766842|PMID:26774285)
RGD PMID:26774285 MGI:MGI:5766842 NCBI chr 7:64,860,641...64,888,146
Ensembl chr 7:64,860,666...64,887,448
JBrowse link
G Wdr70 WD repeat domain 70 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:56,944,462...57,196,522
Ensembl chr 2:56,944,460...57,196,568
JBrowse link
regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek1 checkpoint kinase 1 ISO
ISS
(PMID:15665856)
GO_REF:0000024
RGD
UniProt
PMID:15665856 GO_REF:0000024 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Fign fidgetin, microtubule severing factor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:49,992,250...50,120,601
Ensembl chr 3:49,992,397...50,120,392
JBrowse link
G Fignl1 fidgetin-like 1 ISO
IBA
ISS
(PMID:23754376)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23754376, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr14:91,895,902...91,904,474
Ensembl chr14:91,895,909...91,904,433
JBrowse link
G Kdm1a lysine demethylase 1A ISO (PMID:24217620) RGD PMID:24217620 NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171
JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:20154705)
Ensembl
UniProt
RGD
PMID:20154705 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:198,219,012...198,225,775
Ensembl chr 1:198,219,054...198,225,580
JBrowse link
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 ISO (PMID:20154705) RGD PMID:20154705 NCBI chr 4:133,285,552...133,323,755
Ensembl chr 4:133,285,552...133,323,755
JBrowse link
G Rad51 RAD51 recombinase ISO (PMID:23754376) RGD PMID:23754376 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rad51ap1 RAD51 associated protein 1 ISO (PMID:23754376) RGD PMID:23754376 NCBI chr 4:159,469,803...159,482,869
Ensembl chr 4:159,469,804...159,482,869
JBrowse link
G Rpa2 replication protein A2 ISO
ISS
(PMID:20154705)
GO_REF:0000024
RGD
UniProt
PMID:20154705 GO_REF:0000024 NCBI chr 5:150,957,041...150,967,597
Ensembl chr 5:150,957,001...150,968,269
JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 ISO
IBA
IEA
ISS
(PMID:18957201)
PMID:21873635
GO_REF:0000104
GO_REF:0000024
RGD
UniProt
PMID:18957201, PMID:21873635 GO_REF:0000024, GO_REF:0000104, RGD:13792537 NCBI chr 3:176,818,012...176,856,531
Ensembl chr 3:176,818,437...176,856,531
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO (PMID:24843002) RGD PMID:24843002 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Shld2 shieldin complex subunit 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:10,570,307...10,661,528
Ensembl chr16:10,570,314...10,661,528
JBrowse link
G Sirt6 sirtuin 6 ISO (PMID:19135889) RGD PMID:19135889 NCBI chr 7:10,937,622...10,943,048
Ensembl chr 7:10,937,599...10,943,063
JBrowse link
G Spidr scaffold protein involved in DNA repair ISO (PMID:23754376) RGD PMID:23754376 NCBI chr11:89,009,931...89,260,361
Ensembl chr11:89,009,931...89,260,297
JBrowse link
G Terf2ip TERF2 interacting protein ISO
ISS
(MGI:MGI:4440768|PMID:20339076)
GO_REF:0000024
RGD
UniProt
PMID:20339076 GO_REF:0000024, MGI:MGI:4440768 NCBI chr19:44,231,317...44,238,406
Ensembl chr19:44,231,251...44,238,404
JBrowse link
G Tex15 testis expressed 15, meiosis and synapsis associated ISO MGI:MGI:3526165 (MGI:MGI:3794139|PMID:18283110) RGD PMID:18283110 MGI:MGI:3794139 NCBI chr16:62,313,284...62,373,288
Ensembl chr16:62,313,263...62,373,253
JBrowse link
G Usp51 ubiquitin specific peptidase 51 ISO (PMID:27083998) RGD PMID:27083998 NCBI chr  X:19,268,352...19,273,753
Ensembl chr  X:19,270,181...19,273,139
JBrowse link
G Zfp365 zinc finger protein 365 ISO
ISS
(PMID:23966166)
GO_REF:0000024
RGD
UniProt
PMID:23966166 GO_REF:0000024 NCBI chr20:22,060,160...22,083,766
Ensembl chr20:22,060,224...22,086,108
JBrowse link
regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr2 actin related protein 2 NOT ISS
ISO
GO_REF:0000024
(PMID:29925947)
UniProt
RGD
PMID:29925947 GO_REF:0000024 NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649
JBrowse link
G Dek DEK proto-oncogene ISO MGI:MGI:3838711 (MGI:MGI:5317387|PMID:21653549) RGD PMID:21653549 MGI:MGI:5317387 NCBI chr17:17,965,872...17,987,836
Ensembl chr17:17,965,881...17,987,834
JBrowse link
G Mrnip MRN complex interacting protein ISO (PMID:27568553) RGD PMID:27568553 NCBI chr10:35,680,687...35,704,685
Ensembl chr10:35,680,658...35,704,776
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 ISO (MGI:MGI:5462481|PMID:23241889) RGD PMID:23241889 MGI:MGI:5462481 NCBI chr14:82,119,210...82,196,501
Ensembl chr14:82,119,210...82,171,480
JBrowse link
G Pot1 protection of telomeres 1 ISO (PMID:29227966) RGD PMID:29227966 NCBI chr 4:51,888,632...51,946,764
Ensembl chr 4:51,888,634...51,946,715
JBrowse link
G Sirt7 sirtuin 7 ISS
ISO
GO_REF:0000024
(MGI:MGI:5789069|PMID:27225932)
UniProt
RGD
PMID:27225932 GO_REF:0000024, MGI:MGI:5789069 NCBI chr10:109,796,046...109,802,821
Ensembl chr10:109,796,020...109,802,739
JBrowse link
G Usp51 ubiquitin specific peptidase 51 ISO (PMID:27083998) RGD PMID:27083998 NCBI chr  X:19,268,352...19,273,753
Ensembl chr  X:19,270,181...19,273,139
JBrowse link
G Was WASP actin nucleation promoting factor NOT ISO (PMID:29925947) RGD PMID:29925947 NCBI chr  X:15,155,246...15,164,099
Ensembl chr  X:15,155,230...15,164,105
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      regulation of metabolic process 7007
        regulation of macromolecule metabolic process 6492
          regulation of DNA metabolic process 392
            regulation of DNA repair 130
              regulation of double-strand break repair 85
                negative regulation of double-strand break repair + 30
                positive regulation of double-strand break repair + 40
                regulation of DNA double-strand break processing 2
                regulation of double-strand break repair via homologous recombination + 45
                regulation of double-strand break repair via nonhomologous end joining + 31
                regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends 0
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      cellular metabolic process 11065
        cellular aromatic compound metabolic process 5708
          nucleobase-containing compound metabolic process 5483
            nucleic acid metabolic process 4980
              DNA metabolic process 919
                DNA repair 482
                  regulation of DNA repair 130
                    regulation of double-strand break repair 85
                      negative regulation of double-strand break repair + 30
                      positive regulation of double-strand break repair + 40
                      regulation of DNA double-strand break processing 2
                      regulation of double-strand break repair via homologous recombination + 45
                      regulation of double-strand break repair via nonhomologous end joining + 31
                      regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.