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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of double-strand break repair via nonhomologous end joining
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Accession:GO:2001033 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
Synonyms:exact_synonym: negative regulation of NHEJ


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negative regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aunip aurora kinase A and ninein interacting protein ISO
ISS
(PMID:29042561)
GO_REF:0000024
RGD
UniProt
PMID:29042561 GO_REF:0000024 NCBI chr 5:152,721,799...152,734,577
Ensembl chr 5:152,721,940...152,734,572
JBrowse link
G Cyren cell cycle regulator of NHEJ ISO
ISS
(PMID:28959974)
GO_REF:0000024
RGD
UniProt
PMID:28959974 GO_REF:0000024 NCBI chr 4:62,391,770...62,397,162
Ensembl chr 4:62,391,770...62,396,035
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Hmga2 high mobility group AT-hook 2 ISO
ISS
(PMID:19549901)
GO_REF:0000024
RGD
UniProt
PMID:19549901 GO_REF:0000024 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Hsf1 heat shock transcription factor 1 ISO (PMID:26359349) RGD PMID:26359349 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Nudt16l1 nudix hydrolase 16 like 1 ISO (PMID:28241136) RGD PMID:28241136 NCBI chr10:10,829,866...10,831,782
Ensembl chr10:10,829,867...10,831,782
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    cellular process 18791
      negative regulation of cellular process 5158
        negative regulation of response to DNA damage stimulus 77
          negative regulation of DNA repair 31
            negative regulation of double-strand break repair 30
              negative regulation of double-strand break repair via nonhomologous end joining 6
Path 2
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      cellular metabolic process 11064
        cellular aromatic compound metabolic process 5708
          nucleobase-containing compound metabolic process 5483
            nucleic acid metabolic process 4980
              DNA metabolic process 919
                DNA repair 482
                  regulation of DNA repair 130
                    regulation of double-strand break repair 85
                      regulation of double-strand break repair via nonhomologous end joining 31
                        negative regulation of double-strand break repair via nonhomologous end joining 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.