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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of Rho guanyl-nucleotide exchange factor activity
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Accession:GO:2001107 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
Synonyms:exact_synonym: negative regulation of Rho guanine nucleotide exchange factor;   negative regulation of RhoGEF


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negative regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RIPOR1 RHO family interacting cell polarization regulator 1 ISO (PMID:25588844) UniProtKB PMID:25588844 NCBI chr16:47,872,769...47,890,776
Ensembl chr16:67,268,180...67,278,445
JBrowse link
G RIPOR2 RHO family interacting cell polarization regulator 2 ISO (PMID:23241886)
(MGI:MGI:5887189|PMID:25588844)
UniProtKB PMID:23241886, PMID:25588844 MGI:MGI:5887189 NCBI chr 6:24,642,239...24,768,074
Ensembl chr 6:24,973,412...25,204,745
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12564
    biological regulation 9168
      regulation of molecular function 2243
        regulation of binding 408
          positive regulation of binding 203
            negative regulation of guanyl-nucleotide exchange factor activity 8
              negative regulation of Rho guanyl-nucleotide exchange factor activity 2
Path 2
Term Annotations click to browse term
  biological_process 12564
    biological regulation 9168
      regulation of molecular function 2243
        regulation of binding 408
          regulation of protein binding 237
            negative regulation of protein binding 114
              negative regulation of Ras GTPase binding 2
                negative regulation of Rho guanyl-nucleotide exchange factor activity 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.