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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of Rho guanyl-nucleotide exchange factor activity
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Accession:GO:2001107 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
Synonyms:exact_synonym: negative regulation of Rho guanine nucleotide exchange factor;   negative regulation of RhoGEF


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negative regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ripor1 RHO family interacting cell polarization regulator 1 ISO (PMID:25588844) UniProtKB PMID:25588844 NCBI chrNW_004955484:9,110,208...9,119,678 JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 ISO (MGI:MGI:5887189|PMID:25588844)
(PMID:23241886)
UniProtKB PMID:23241886, PMID:25588844 MGI:MGI:5887189 NCBI chrNW_004955483:2,048,236...2,257,078 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11862
    negative regulation of biological process 4623
      negative regulation of guanyl-nucleotide exchange factor activity 8
        negative regulation of Rho guanyl-nucleotide exchange factor activity 2
Path 2
Term Annotations click to browse term
  biological_process 11862
    biological regulation 8697
      regulation of molecular function 2145
        regulation of binding 390
          regulation of protein binding 227
            regulation of guanyl-nucleotide exchange factor activity 10
              negative regulation of guanyl-nucleotide exchange factor activity 8
                negative regulation of Rho guanyl-nucleotide exchange factor activity 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.