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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of Rho guanyl-nucleotide exchange factor activity
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Accession:GO:2001107 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
Synonyms:exact_synonym: negative regulation of Rho guanine nucleotide exchange factor;   negative regulation of RhoGEF


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negative regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RIPOR1 RHO family interacting cell polarization regulator 1 ISO (PMID:25588844) UniProtKB PMID:25588844 NCBI chr 5:81,879,359...81,888,613
Ensembl chr 5:81,879,652...81,887,650
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G RIPOR2 RHO family interacting cell polarization regulator 2 IEA Ensembl GO_REF:0000107 NCBI chr35:22,823,053...23,041,765
Ensembl chr35:22,824,106...23,041,743
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16190
    biological regulation 11558
      regulation of molecular function 2823
        negative regulation of molecular function 1104
          negative regulation of guanyl-nucleotide exchange factor activity 8
            negative regulation of Rho guanyl-nucleotide exchange factor activity 2
Path 2
Term Annotations click to browse term
  biological_process 16190
    biological regulation 11558
      regulation of molecular function 2823
        regulation of catalytic activity 2139
          regulation of hydrolase activity 1166
            regulation of GTPase activity 416
              regulation of guanyl-nucleotide exchange factor activity 12
                negative regulation of guanyl-nucleotide exchange factor activity 8
                  negative regulation of Rho guanyl-nucleotide exchange factor activity 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.