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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of Rho guanyl-nucleotide exchange factor activity
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Accession:GO:2001107 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
Synonyms:exact_synonym: negative regulation of Rho guanine nucleotide exchange factor;   negative regulation of RhoGEF


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negative regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ripor1 RHO family interacting cell polarization regulator 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 8:105,594,087...105,622,219
Ensembl chr 8:105,605,255...105,622,219
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G Ripor2 RHO family interacting cell polarization regulator 2 IMP
ISO
(MGI:MGI:5887189|PMID:25588844) UniProtKB
MGI
PMID:25588844 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:5887189 NCBI chr13:24,501,524...24,733,806
Ensembl chr13:24,501,525...24,733,816
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23360
    negative regulation of biological process 5678
      negative regulation of guanyl-nucleotide exchange factor activity 8
        negative regulation of Rho guanyl-nucleotide exchange factor activity 2
Path 2
Term Annotations click to browse term
  biological_process 23360
    biological regulation 13063
      regulation of molecular function 2716
        regulation of binding 413
          regulation of protein binding 238
            regulation of guanyl-nucleotide exchange factor activity 12
              negative regulation of guanyl-nucleotide exchange factor activity 8
                negative regulation of Rho guanyl-nucleotide exchange factor activity 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.