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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of Rho guanyl-nucleotide exchange factor activity
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Accession:GO:2001107 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
Synonyms:exact_synonym: negative regulation of Rho guanine nucleotide exchange factor;   negative regulation of RhoGEF


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negative regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RIPOR1 RHO family interacting cell polarization regulator 1 ISO (PMID:25588844) UniProtKB PMID:25588844 NCBI chr 6:28,156,508...28,183,640
Ensembl chr 6:28,132,115...28,183,788
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G RIPOR2 RHO family interacting cell polarization regulator 2 IEA Ensembl GO_REF:0000107 NCBI chr 7:19,609,358...19,842,345
Ensembl chr 7:19,587,685...19,838,093
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16548
    biological regulation 12014
      regulation of molecular function 2830
        negative regulation of molecular function 1110
          negative regulation of guanyl-nucleotide exchange factor activity 8
            negative regulation of Rho guanyl-nucleotide exchange factor activity 2
Path 2
Term Annotations click to browse term
  biological_process 16548
    biological regulation 12014
      regulation of molecular function 2830
        regulation of catalytic activity 2142
          regulation of hydrolase activity 1163
            regulation of GTPase activity 412
              regulation of guanyl-nucleotide exchange factor activity 11
                negative regulation of guanyl-nucleotide exchange factor activity 8
                  negative regulation of Rho guanyl-nucleotide exchange factor activity 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.