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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of Rho guanyl-nucleotide exchange factor activity
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Accession:GO:2001107 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
Synonyms:exact_synonym: negative regulation of Rho guanine nucleotide exchange factor;   negative regulation of RhoGEF


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negative regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ripor1 RHO family interacting cell polarization regulator 1 ISO (PMID:25588844) RGD PMID:25588844 NCBI chr19:37,555,940...37,584,842
Ensembl chr19:37,568,113...37,587,294
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G Ripor2 RHO family interacting cell polarization regulator 2 ISO
ISS
(PMID:23241886)
(MGI:5887189|PMID:25588844)
GO_REF:0000024
RGD
UniProt
PMID:23241886, PMID:25588844 GO_REF:0000024, MGI:5887189 NCBI chr17:42,324,594...42,549,907
Ensembl chr17:42,324,594...42,422,053
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of molecular function 3074
        negative regulation of molecular function 1226
          negative regulation of guanyl-nucleotide exchange factor activity 8
            negative regulation of Rho guanyl-nucleotide exchange factor activity 2
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of molecular function 3074
        regulation of catalytic activity 2350
          regulation of hydrolase activity 1307
            regulation of GTPase activity 442
              regulation of guanyl-nucleotide exchange factor activity 12
                negative regulation of guanyl-nucleotide exchange factor activity 8
                  negative regulation of Rho guanyl-nucleotide exchange factor activity 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.