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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of intrinsic apoptotic signaling pathway
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Accession:GO:2001242 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.
Synonyms:exact_synonym: regulation of intrinsic apoptotic pathway;   regulation of intrinsic apoptotic signalling pathway;   regulation of mitochondrial-mediated apoptotic pathway
 narrow_synonym: regulation of intrinsic apoptosis


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regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyld CYLD lysine 63 deubiquitinase JBrowse link 19 19,264,984 19,323,817 RGD:1600115
RGD:13792537
RGD:1624291
G Dapk2 death-associated protein kinase 2 JBrowse link 8 71,822,107 71,941,941 RGD:1624291
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 JBrowse link 3 79,734,961 79,743,737 RGD:1600115
RGD:1624291
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
G Styxl1 serine/threonine/tyrosine interacting-like 1 JBrowse link 12 23,954,563 23,987,155 RGD:1624291
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:1600115
RGD:1624291
G Creb3 cAMP responsive element binding protein 3 JBrowse link 5 59,063,532 59,068,196 RGD:1624291
G Creb3l1 cAMP responsive element binding protein 3-like 1 JBrowse link 3 80,892,433 80,933,283 RGD:1558627
RGD:1624291
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 JBrowse link 7 117,304,742 117,307,916 RGD:1624291
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1304324
RGD:13792537
RGD:1624291
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1624291
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:1624291
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:10047230
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:1624291
RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:1624291
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291
RGD:1600115
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291
G Selenos selenoprotein S JBrowse link 1 126,979,579 126,989,344 RGD:1624291
RGD:1600115
G Syvn1 synoviolin 1 JBrowse link 1 221,409,281 221,416,229 RGD:1624291
G Tmbim6 transmembrane BAX inhibitor motif containing 6 JBrowse link 7 141,039,433 141,070,269 RGD:1624291
RGD:1600115
G Txndc12 thioredoxin domain containing 12 JBrowse link 5 128,450,830 128,475,858 RGD:1624291
G Wfs1 wolframin ER transmembrane glycoprotein JBrowse link 14 78,640,707 78,665,224 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
RGD:10047191
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hyou1 hypoxia up-regulated 1 JBrowse link 8 48,699,796 48,711,912 RGD:1624291
RGD:1600115
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:1624291
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eno1 enolase 1 JBrowse link 5 167,288,223 167,299,610 RGD:1624291
G Hyou1 hypoxia up-regulated 1 JBrowse link 8 48,699,796 48,711,912 RGD:1624291
RGD:13792537
RGD:1600115
RGD:10047348
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:12793039
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:10047155
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:1624291
G Tmbim6 transmembrane BAX inhibitor motif containing 6 JBrowse link 7 141,039,433 141,070,269 RGD:1624291
RGD:1600115
negative regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC098008.1 RGD:13792537
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1600115
RGD:1624291
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1600115
RGD:13792537
RGD:1624291
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:1624291
RGD:13792537
G Bcl2l10 BCL2 like 10 JBrowse link 8 82,288,705 82,294,750 RGD:1624291
RGD:13792537
G Bcl2l2 Bcl2-like 2 JBrowse link 15 33,543,774 33,549,165 RGD:13792537
G Ddx3x DEAD-box helicase 3, X-linked JBrowse link X 10,400,363 10,414,010 RGD:1624291
G Fignl1 fidgetin-like 1 JBrowse link 14 91,895,902 91,904,474 RGD:1624291
G G2e3 G2/M-phase specific E3 ubiquitin protein ligase JBrowse link 6 72,092,148 72,123,878 RGD:1624291
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:1624291
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:1624291
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:1624291
G Hells helicase, lymphoid specific JBrowse link 1 257,901,856 257,953,889 RGD:1624291
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1624291
RGD:10047316
G Ivns1abp influenza virus NS1A binding protein JBrowse link 13 68,702,970 68,722,472 RGD:1624291
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 JBrowse link 3 81,295,023 81,304,181 RGD:1624291
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 2 197,786,212 197,788,992 RGD:13792537
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:1624291
RGD:1600115
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 JBrowse link 16 21,275,311 21,282,246 RGD:1624291
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 JBrowse link 3 79,721,686 79,728,863 RGD:1624291
G Noc2l NOC2-like nucleolar associated transcriptional repressor JBrowse link 5 173,659,796 173,672,699 RGD:1624291
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:10047289
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:1624291
G Parl presenilin associated, rhomboid-like JBrowse link 11 84,517,368 84,544,463 RGD:1600115
RGD:1624291
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:1624291
G Plaur plasminogen activator, urokinase receptor JBrowse link 1 81,328,171 81,344,954 RGD:1624291
RGD:1600115
G Ppif peptidylprolyl isomerase F JBrowse link 16 1,979,191 1,985,912 RGD:1624291
RGD:1600115
G Rtkn2 rhotekin 2 JBrowse link 20 21,919,486 22,004,279 RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
RGD:13792537
G Uri1 URI1, prefoldin-like chaperone JBrowse link 1 94,346,513 94,404,362 RGD:1624291
G Vdac2 voltage-dependent anion channel 2 JBrowse link 15 2,634,622 2,648,548 RGD:1624291
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Armc10 armadillo repeat containing 10 JBrowse link 4 10,004,846 10,020,017 RGD:1624291
G Cep63 centrosomal protein 63 JBrowse link 8 111,063,988 111,116,014 RGD:1624291
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:1624291
G Mdm4 MDM4 regulator of p53 JBrowse link 13 49,786,776 49,828,780 RGD:1624291
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291
G Pttg1ip PTTG1 interacting protein JBrowse link 20 11,746,369 11,764,097 RGD:1624291
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B JBrowse link 7 76,750,045 76,780,817 RGD:1624291
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor JBrowse link 10 3,170,387 3,214,648 RGD:1624291
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 JBrowse link 2 250,709,812 250,744,216 RGD:1624291
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ackr3 atypical chemokine receptor 3 JBrowse link 9 97,355,881 97,367,455 RGD:1624291
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 10 67,427,042 67,475,825 RGD:1624291
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:1624291
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:1624291
G Ccar2 cell cycle and apoptosis regulator 2 JBrowse link 15 51,818,887 51,834,443 RGD:1624291
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:1624291
RGD:1600115
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:1624291
G Ddias DNA damage-induced apoptosis suppressor JBrowse link 1 157,675,754 157,700,064 RGD:1624291
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:1624291
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
G Tmem161a transmembrane protein 161A JBrowse link 16 20,985,841 20,996,351 RGD:1624291
G Tpt1 tumor protein, translationally-controlled 1 JBrowse link 15 57,891,680 57,894,504 RGD:1624291
G Trim32 tripartite motif-containing 32 JBrowse link 5 81,431,554 81,449,023 RGD:1624291
G Usp47 ubiquitin specific peptidase 47 JBrowse link 1 176,854,589 176,937,763 RGD:1624291
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 10 67,427,042 67,475,825 RGD:1624291
G Bcl2l12 BCL2 like 12 JBrowse link 1 100,984,550 100,993,269 RGD:1624291
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:1624291
RGD:1600115
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
RGD:1600115
G Ell3 elongation factor for RNA polymerase II 3 JBrowse link 3 113,400,395 113,405,869 RGD:1624291
G Kdm1a lysine demethylase 1A JBrowse link 5 154,909,003 154,965,171 RGD:1624291
G Marchf7 membrane associated ring-CH-type finger 7 JBrowse link 3 46,284,961 46,325,230 RGD:1624291
RGD:1600115
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1624291
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Triap1 TP53 regulated inhibitor of apoptosis 1 JBrowse link 12 46,987,404 46,989,906 RGD:1624291
G Zfp385a zinc finger protein 385A JBrowse link 7 144,939,616 144,966,364 RGD:1624291
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsph1 heat shock protein family H (Hsp110) member 1 JBrowse link 12 6,322,685 6,341,898 RGD:1624291
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:8693356
RGD:1624291
G Trap1 TNF receptor-associated protein 1 JBrowse link 10 11,724,032 11,757,682 RGD:8693356
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1624291
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:1624291
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:1624291
G Ptger2 prostaglandin E receptor 2 JBrowse link 15 19,336,029 19,349,759 RGD:1624291
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1624291
G Ybx3 Y box binding protein 3 JBrowse link 4 165,606,819 165,630,041 RGD:1624291
RGD:1600115
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:1624291
RGD:1600115
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 JBrowse link 5 57,028,467 57,039,378 RGD:1624291
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bag5 BAG cochaperone 5 JBrowse link 6 136,180,640 136,185,651 RGD:1624291
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:1624291
RGD:1600115
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:1624291
RGD:1600115
G Mapk7 mitogen-activated protein kinase 7 JBrowse link 10 47,768,592 47,775,130 RGD:1624291
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:1624291
G Nme5 NME/NM23 family member 5 JBrowse link 18 27,357,460 27,374,641 RGD:1624291
RGD:13792537
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
RGD:1600115
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:1624291
G Vnn1 vanin 1 JBrowse link 1 22,614,832 22,625,134 RGD:1624291
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Nono non-POU domain containing, octamer-binding JBrowse link X 71,324,365 71,342,225 RGD:1624291
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291
RGD:1600115
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bok BCL2 family apoptosis regulator BOK JBrowse link 9 100,829,593 100,840,498 RGD:1600115
RGD:1624291
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
G Rnf183 ring finger protein 183 JBrowse link 5 78,283,722 78,292,729 RGD:1624291
G Serinc3 serine incorporator 3 JBrowse link 3 160,018,643 160,038,078 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Spop speckle type BTB/POZ protein JBrowse link 10 83,231,187 83,311,987 RGD:1624291
positive regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Bbc3 Bcl-2 binding component 3 JBrowse link 1 78,261,491 78,267,802 RGD:1600115
RGD:1624291
RGD:14390051
G Bcap31 B-cell receptor-associated protein 31 JBrowse link X 157,094,365 157,126,397 RGD:1624291
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:1624291
G Bclaf1 BCL2-associated transcription factor 1 JBrowse link 1 15,799,753 15,828,838 RGD:1624291
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:1600115
RGD:1624291
RGD:14390051
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:1624291
RGD:13792537
G Bok BCL2 family apoptosis regulator BOK JBrowse link 9 100,829,593 100,840,498 RGD:1624291
RGD:1600115
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase JBrowse link 3 120,373,604 120,404,910 RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1600115
RGD:1624291
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:1624291
RGD:1600115
G Cyct cytochrome c, testis JBrowse link 3 63,204,779 63,211,847 RGD:1624291
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:1600115
RGD:13792537
RGD:1624291
RGD:14390051
G Dnm1l dynamin 1-like JBrowse link 11 88,830,968 88,882,271 RGD:1624291
G Ei24 EI24, autophagy associated transmembrane protein JBrowse link 8 39,254,883 39,271,238 RGD:1624291
G Fis1 fission, mitochondrial 1 JBrowse link 12 22,750,485 22,765,324 RGD:1624291
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:1624291
G Gsdme gasdermin E JBrowse link 4 79,934,075 79,999,678 RGD:1624291
RGD:1600115
G Il19 interleukin 19 JBrowse link 13 47,663,592 47,677,869 RGD:1624291
G Il20ra interleukin 20 receptor subunit alpha JBrowse link 1 15,180,328 15,222,785 RGD:1624291
G Lck LCK proto-oncogene, Src family tyrosine kinase JBrowse link 5 147,750,976 147,779,627 RGD:1624291
RGD:1600115
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1624291
RGD:1600115
G Nupr1 nuclear protein 1, transcriptional regulator JBrowse link 1 194,767,484 194,769,519 RGD:1600115
RGD:1624291
RGD:14390051
G Plagl2 PLAG1 like zinc finger 2 JBrowse link 3 148,709,564 148,722,777 RGD:1624291
G Plekhf1 pleckstrin homology and FYVE domain containing 1 JBrowse link 1 94,609,041 94,616,565 RGD:1624291
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 62,159,128 62,179,635 RGD:1624291
G Prkra protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 3 63,489,081 63,507,918 RGD:1624291
RGD:1600115
G Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:1624291
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 15 34,470,796 34,479,741 RGD:1624291
G S100a8 S100 calcium binding protein A8 JBrowse link 2 190,073,239 190,074,333 RGD:1624291
RGD:1600115
G S100a9 S100 calcium binding protein A9 JBrowse link 2 190,097,436 190,100,209 RGD:1600115
RGD:1624291
G Septin4 septin 4 JBrowse link 10 74,860,068 74,884,196 RGD:1624291
G Siah1 siah E3 ubiquitin protein ligase 1 JBrowse link 19 21,372,163 21,395,773 RGD:1624291
G Slc9a3r1 SLC9A3 regulator 1 JBrowse link 10 103,713,045 103,730,145 RGD:1624291
G Styxl1 serine/threonine/tyrosine interacting-like 1 JBrowse link 12 23,954,563 23,987,155 RGD:1624291
RGD:13792537
G Taf6 TATA-box binding protein associated factor 6 JBrowse link 12 19,320,269 19,328,706 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1600115
RGD:1624291
RGD:14390051
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Msx1 msh homeobox 1 JBrowse link 14 77,712,262 77,716,061 RGD:1624291
G Rpl11 ribosomal protein L11 JBrowse link 5 154,390,809 154,394,412 RGD:1624291
RGD:1600115
G Rps7 ribosomal protein S7 JBrowse link 6 47,899,525 47,904,389 RGD:1624291
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 JBrowse link 2 250,709,812 250,744,216 RGD:1624291
G Ubb ubiquitin B JBrowse link 10 48,880,231 48,881,896 RGD:1624291
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbh1 F-box DNA helicase 1 JBrowse link 17 70,399,093 70,437,151 RGD:1624291
G Mtch2 mitochondrial carrier 2 JBrowse link 3 79,678,141 79,695,356 RGD:1624291
G Nacc2 NACC family member 2 JBrowse link 3 3,508,084 3,574,787 RGD:1624291
RGD:1600115
G Pias4 protein inhibitor of activated STAT, 4 JBrowse link 7 11,414,565 11,428,090 RGD:1624291
G Plscr1 phospholipid scramblase 1 JBrowse link 8 99,625,523 99,645,882 RGD:1624291
RGD:1600115
G Rad9a RAD9 checkpoint clamp component A JBrowse link 1 219,443,347 219,450,574 RGD:1624291
G Rps3 ribosomal protein S3 JBrowse link 1 164,435,868 164,441,167 RGD:1624291
G Skil SKI-like proto-oncogene JBrowse link 2 115,862,932 115,891,304 RGD:1624291
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rpl26 ribosomal protein L26 JBrowse link 10 55,492,417 55,495,547 RGD:1624291
G Steap3 STEAP3 metalloreductase JBrowse link 13 36,257,220 36,274,144 RGD:1624291
G Tp73 tumor protein p73 JBrowse link 5 171,355,876 171,415,354 RGD:1624291
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nox1 NADPH oxidase 1 JBrowse link X 104,909,328 104,932,508 RGD:1624291
RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
G Sfpq splicing factor proline and glutamine rich JBrowse link 5 145,079,803 145,088,517 RGD:1624291
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1624291
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbxw7 F-box and WD repeat domain containing 7 JBrowse link 2 184,230,191 184,309,805 RGD:1624291
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 2 197,786,212 197,788,992 RGD:1624291
G Ralbp1 ralA binding protein 1 JBrowse link 9 113,579,107 113,598,477 RGD:12904719
regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
G Erp29 endoplasmic reticulum protein 29 JBrowse link 12 40,619,377 40,625,884 RGD:1624291
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1624291
regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd2 ankyrin repeat domain 2 JBrowse link 1 261,281,859 261,291,307 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hnrnpk heterogeneous nuclear ribonucleoprotein K JBrowse link 17 6,664,730 6,676,753 RGD:1624291
regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G P4hb prolyl 4-hydroxylase subunit beta JBrowse link 10 109,736,459 109,748,070 RGD:1624291
G Ubqln1 ubiquilin 1 JBrowse link 17 6,840,441 6,878,842 RGD:1624291
RGD:1600115
regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:10414071

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19404
    cellular process 18142
      signal transduction 6884
        intracellular signal transduction 2593
          intrinsic apoptotic signaling pathway 301
            regulation of intrinsic apoptotic signaling pathway 177
              negative regulation of intrinsic apoptotic signaling pathway + 104
              positive regulation of intrinsic apoptotic signaling pathway + 69
              regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway + 32
              regulation of hypoxia-induced intrinsic apoptotic signaling pathway + 6
              regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 32
              regulation of intrinsic apoptotic signaling pathway in response to DNA damage + 38
              regulation of intrinsic apoptotic signaling pathway in response to osmotic stress + 7
              regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway + 2
              regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 26
Path 2
Term Annotations click to browse term
  biological_process 19404
    biological regulation 13421
      regulation of biological process 12724
        regulation of cellular process 12223
          regulation of cell death 1771
            regulation of programmed cell death 1603
              regulation of apoptotic process 1576
                regulation of apoptotic signaling pathway 424
                  regulation of intrinsic apoptotic signaling pathway 177
                    negative regulation of intrinsic apoptotic signaling pathway + 104
                    positive regulation of intrinsic apoptotic signaling pathway + 69
                    regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway + 32
                    regulation of hypoxia-induced intrinsic apoptotic signaling pathway + 6
                    regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 32
                    regulation of intrinsic apoptotic signaling pathway in response to DNA damage + 38
                    regulation of intrinsic apoptotic signaling pathway in response to osmotic stress + 7
                    regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway + 2
                    regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 26
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.