Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of intrinsic apoptotic signaling pathway
go back to main search page
Accession:GO:2001244 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.
Synonyms:exact_synonym: positive regulation of intrinsic apoptotic pathway;   positive regulation of intrinsic apoptotic signalling pathway;   positive regulation of mitochondrial-mediated apoptotic pathway
 narrow_synonym: positive regulation of intrinsic apoptosis


show annotations for term's descendants       view all columns           Sort by:
 
positive regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Bbc3 Bcl-2 binding component 3 JBrowse link 1 78,261,491 78,267,802 RGD:1600115
RGD:1624291
RGD:14390051
G Bcap31 B-cell receptor-associated protein 31 JBrowse link X 157,094,365 157,126,397 RGD:1624291
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:1624291
G Bclaf1 BCL2-associated transcription factor 1 JBrowse link 1 15,799,753 15,828,838 RGD:1624291
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:1600115
RGD:1624291
RGD:14390051
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:1624291
RGD:13792537
G Bok BCL2 family apoptosis regulator BOK JBrowse link 9 100,829,593 100,840,498 RGD:1624291
RGD:1600115
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase JBrowse link 3 120,373,604 120,404,910 RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1600115
RGD:1624291
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:1624291
RGD:1600115
G Cyct cytochrome c, testis JBrowse link 3 63,204,779 63,211,847 RGD:1624291
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:1600115
RGD:13792537
RGD:1624291
RGD:14390051
G Dnm1l dynamin 1-like JBrowse link 11 88,830,968 88,882,271 RGD:1624291
G Ei24 EI24, autophagy associated transmembrane protein JBrowse link 8 39,254,883 39,271,238 RGD:1624291
G Fis1 fission, mitochondrial 1 JBrowse link 12 22,750,485 22,765,324 RGD:1624291
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:1624291
G Gsdme gasdermin E JBrowse link 4 79,934,075 79,999,678 RGD:1624291
RGD:1600115
G Il19 interleukin 19 JBrowse link 13 47,663,592 47,677,869 RGD:1624291
G Il20ra interleukin 20 receptor subunit alpha JBrowse link 1 15,180,328 15,222,785 RGD:1624291
G Lck LCK proto-oncogene, Src family tyrosine kinase JBrowse link 5 147,750,976 147,779,627 RGD:1624291
RGD:1600115
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1624291
RGD:1600115
G Nupr1 nuclear protein 1, transcriptional regulator JBrowse link 1 194,767,484 194,769,519 RGD:1600115
RGD:1624291
RGD:14390051
G Plagl2 PLAG1 like zinc finger 2 JBrowse link 3 148,709,564 148,722,777 RGD:1624291
G Plekhf1 pleckstrin homology and FYVE domain containing 1 JBrowse link 1 94,609,041 94,616,565 RGD:1624291
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 62,159,128 62,179,635 RGD:1624291
G Prkra protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 3 63,489,081 63,507,918 RGD:1624291
RGD:1600115
G Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:1624291
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 15 34,470,796 34,479,741 RGD:1624291
G S100a8 S100 calcium binding protein A8 JBrowse link 2 190,073,239 190,074,333 RGD:1624291
RGD:1600115
G S100a9 S100 calcium binding protein A9 JBrowse link 2 190,097,436 190,100,209 RGD:1600115
RGD:1624291
G Septin4 septin 4 JBrowse link 10 74,860,068 74,884,196 RGD:1624291
G Siah1 siah E3 ubiquitin protein ligase 1 JBrowse link 19 21,372,163 21,395,773 RGD:1624291
G Slc9a3r1 SLC9A3 regulator 1 JBrowse link 10 103,713,045 103,730,145 RGD:1624291
G Styxl1 serine/threonine/tyrosine interacting-like 1 JBrowse link 12 23,954,563 23,987,155 RGD:1624291
RGD:13792537
G Taf6 TATA-box binding protein associated factor 6 JBrowse link 12 19,320,269 19,328,706 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1600115
RGD:1624291
RGD:14390051
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bok BCL2 family apoptosis regulator BOK JBrowse link 9 100,829,593 100,840,498 RGD:1600115
RGD:1624291
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
G Rnf183 ring finger protein 183 JBrowse link 5 78,283,722 78,292,729 RGD:1624291
G Serinc3 serine incorporator 3 JBrowse link 3 160,018,643 160,038,078 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Spop speckle type BTB/POZ protein JBrowse link 10 83,231,187 83,311,987 RGD:1624291
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Msx1 msh homeobox 1 JBrowse link 14 77,712,262 77,716,061 RGD:1624291
G Rpl11 ribosomal protein L11 JBrowse link 5 154,390,809 154,394,412 RGD:1624291
RGD:1600115
G Rps7 ribosomal protein S7 JBrowse link 6 47,899,525 47,904,389 RGD:1624291
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 JBrowse link 2 250,709,812 250,744,216 RGD:1624291
G Ubb ubiquitin B JBrowse link 10 48,880,231 48,881,896 RGD:1624291
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbh1 F-box DNA helicase 1 JBrowse link 17 70,399,093 70,437,151 RGD:1624291
G Mtch2 mitochondrial carrier 2 JBrowse link 3 79,678,141 79,695,356 RGD:1624291
G Nacc2 NACC family member 2 JBrowse link 3 3,508,084 3,574,787 RGD:1624291
RGD:1600115
G Pias4 protein inhibitor of activated STAT, 4 JBrowse link 7 11,414,565 11,428,090 RGD:1624291
G Plscr1 phospholipid scramblase 1 JBrowse link 8 99,625,523 99,645,882 RGD:1624291
RGD:1600115
G Rad9a RAD9 checkpoint clamp component A JBrowse link 1 219,443,347 219,450,574 RGD:1624291
G Rps3 ribosomal protein S3 JBrowse link 1 164,435,868 164,441,167 RGD:1624291
G Skil SKI-like proto-oncogene JBrowse link 2 115,862,932 115,891,304 RGD:1624291
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rpl26 ribosomal protein L26 JBrowse link 10 55,492,417 55,495,547 RGD:1624291
G Steap3 STEAP3 metalloreductase JBrowse link 13 36,257,220 36,274,144 RGD:1624291
G Tp73 tumor protein p73 JBrowse link 5 171,355,876 171,415,354 RGD:1624291
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nox1 NADPH oxidase 1 JBrowse link X 104,909,328 104,932,508 RGD:1624291
RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
G Sfpq splicing factor proline and glutamine rich JBrowse link 5 145,079,803 145,088,517 RGD:1624291
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1624291
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbxw7 F-box and WD repeat domain containing 7 JBrowse link 2 184,230,191 184,309,805 RGD:1624291
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 2 197,786,212 197,788,992 RGD:1624291
G Ralbp1 ralA binding protein 1 JBrowse link 9 113,579,107 113,598,477 RGD:12904719

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    cellular process 17241
      signal transduction 6872
        intracellular signal transduction 2584
          intrinsic apoptotic signaling pathway 300
            positive regulation of intrinsic apoptotic signaling pathway 69
              positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 9
              positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 8
              positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage + 11
              positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress + 1
              positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway 0
              positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 7
Path 2
Term Annotations click to browse term
  biological_process 19336
    biological regulation 13340
      regulation of biological process 12655
        positive regulation of biological process 6411
          positive regulation of cellular process 5747
            positive regulation of cell death 746
              positive regulation of programmed cell death 678
                positive regulation of apoptotic process 672
                  positive regulation of apoptotic signaling pathway 186
                    positive regulation of intrinsic apoptotic signaling pathway 69
                      positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 9
                      positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 8
                      positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage + 11
                      positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress + 1
                      positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway 0
                      positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 7
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.