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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cation channel activity
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Accession:GO:2001259 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of cation channel activity.
Synonyms:exact_synonym: positive regulation of cation diffusion facilitator activity;   positive regulation of nonselective cation channel activity


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positive regulation of cation channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actn2 actinin alpha 2 JBrowse link 17 66,304,530 66,397,647 RGD:1624291
RGD:1600115
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:6893581
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Ank3 ankyrin 3 JBrowse link 20 19,948,767 20,480,628 RGD:6767295
G Asic2 acid sensing ion channel subunit 2 JBrowse link 10 68,247,800 69,347,223 RGD:1298620
G Ctss cathepsin S JBrowse link 2 197,655,780 197,679,768 RGD:1624291
RGD:1600115
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 JBrowse link 2 50,099,576 50,499,799 RGD:9686372
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:1624291
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 JBrowse link 1 102,103,093 102,107,134 RGD:7296920
G Nedd4l NEDD4 like E3 ubiquitin protein ligase JBrowse link 18 60,392,376 60,719,720 RGD:1624291
G Ntsr1 neurotensin receptor 1 JBrowse link 3 175,982,313 176,046,345 RGD:9743912
G Pirt phosphoinositide-interacting regulator of transient receptor potential channels JBrowse link 10 53,466,870 53,485,096 RGD:1624291
RGD:13792537
G Stac SH3 and cysteine rich domain JBrowse link 8 119,820,664 119,941,867 RGD:1624291
activation of store-operated calcium channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asph aspartate-beta-hydroxylase JBrowse link 5 22,577,680 22,799,333 RGD:1624291
G Cracr2a calcium release activated channel regulator 2A JBrowse link 4 160,143,160 160,238,744 RGD:1624291
RGD:1600115
G Plcg2 phospholipase C, gamma 2 JBrowse link 19 50,039,410 50,173,543 RGD:1624291
RGD:1600115
G Stim1 stromal interaction molecule 1 JBrowse link 1 167,373,894 167,533,412 RGD:7175076
RGD:13792537
RGD:1624291
RGD:1600115
G Stim2 stromal interaction molecule 2 JBrowse link 14 59,198,180 59,323,947 RGD:7175076
RGD:13792537
RGD:1624291
G Tmem110 transmembrane protein 110 JBrowse link 16 6,903,212 6,958,786 RGD:1600115
RGD:13792537
positive regulation of AMPA receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:1600115
RGD:1624291
G Arc activity-regulated cytoskeleton-associated protein JBrowse link 7 115,907,097 115,911,059 RGD:10047209
RGD:13792537
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 JBrowse link 7 119,228,112 119,353,332 RGD:13515081
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 JBrowse link 1 192,613,766 192,708,371 RGD:13515082
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 JBrowse link 10 95,954,160 96,015,484 RGD:13515082
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 JBrowse link 1 64,330,106 64,350,338 RGD:13515082
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1624291
RGD:1600115
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:1624291
RGD:1600115
positive regulation of delayed rectifier potassium channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap6 A-kinase anchoring protein 6 JBrowse link 6 73,553,111 73,991,992 RGD:1624291
RGD:1600115
G Akap7 A-kinase anchoring protein 7 JBrowse link 1 21,129,213 21,263,850 RGD:1624291
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:10047161
RGD:1624291
G Rnf207 ring finger protein 207 JBrowse link 5 169,486,253 169,500,451 RGD:1624291
RGD:1600115
positive regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 JBrowse link 4 15,706,974 16,130,848 RGD:11059598
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 JBrowse link 17 81,673,862 82,019,219 RGD:11059570
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 JBrowse link 7 140,311,120 140,324,902 RGD:13514092
RGD:13673808
G Fgf14 fibroblast growth factor 14 JBrowse link 15 110,382,274 111,077,027 RGD:1624291
RGD:10047342
G Nipsnap2 nipsnap homolog 2 JBrowse link 12 30,527,540 30,566,090 RGD:1624291
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hap1 huntingtin-associated protein 1 JBrowse link 10 88,257,975 88,266,210 RGD:6482800
RGD:1600115
RGD:1624291
G Htt huntingtin JBrowse link 14 81,105,139 81,254,637 RGD:1600115
RGD:1624291
G P2ry6 pyrimidinergic receptor P2Y6 JBrowse link 1 165,972,439 166,008,348 RGD:13673830
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
RGD:1600115
positive regulation of inward rectifier potassium channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 9 14,611,541 14,618,076 RGD:1624291
positive regulation of large conductance calcium-activated potassium channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gal galanin and GMAP prepropeptide JBrowse link 1 218,653,059 218,657,922 RGD:1624291
RGD:1600115
G Galr2 galanin receptor 2 JBrowse link 10 105,156,793 105,159,221 RGD:1600115
RGD:1624291
G LOC103690156 galanin receptor type 2 JBrowse link 10 105,234,244 105,241,704 RGD:1600115
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link 1 248,982,039 250,300,952 RGD:7777099
positive regulation of NMDA glutamate receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:14397550
G Ccr2 C-C motif chemokine receptor 2 RGD:14397550
G Cfl1 cofilin 1 JBrowse link 1 220,869,805 220,873,337 RGD:11570552
G Ephb2 Eph receptor B2 JBrowse link 5 155,024,478 155,143,539 RGD:1624291
RGD:1600115
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:14397550
G Ifngr1 interferon gamma receptor 1 JBrowse link 1 15,062,380 15,080,815 RGD:14397550
G Ifngr2 interferon gamma receptor 2 JBrowse link 11 31,694,339 31,712,611 RGD:14397550
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:13463453
G Rgs9 regulator of G-protein signaling 9 JBrowse link 10 97,509,971 97,582,188 RGD:1599994
positive regulation of proton-transporting ATP synthase activity, rotational mechanism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atpsckmt ATP synthase c subunit lysine N-methyltransferase JBrowse link 2 84,678,892 84,694,152 RGD:1600115
RGD:1624291
G Tmsb4x thymosin beta 4, X-linked JBrowse link X 28,593,405 28,617,267 RGD:1624291
positive regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap6 A-kinase anchoring protein 6 JBrowse link 6 73,553,111 73,991,992 RGD:8554839
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:1624291
RGD:1600115
G Calm2 calmodulin 2 JBrowse link 6 11,067,675 11,080,078 RGD:1624291
RGD:1600115
G Calm3 calmodulin 3 JBrowse link 1 78,844,520 78,851,628 RGD:1624291
RGD:1600115
G Gstm2 glutathione S-transferase mu 2 JBrowse link 2 210,778,041 210,782,807 RGD:1624291
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:1624291
RGD:1600115
G Jph2 junctophilin 2 JBrowse link 3 159,709,998 159,776,536 RGD:1624291
RGD:1600115
G Trdn triadin JBrowse link 1 25,403,390 25,787,664 RGD:1624291
RGD:13792537
positive regulation of store-operated calcium channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:8801954
G Casq1 calsequestrin 1 JBrowse link 13 90,592,676 90,602,365 RGD:1600115
RGD:1624291
positive regulation of voltage-gated calcium channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 JBrowse link 4 15,706,974 16,130,848 RGD:13514093
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 JBrowse link 7 140,311,120 140,324,902 RGD:13514097
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 JBrowse link 3 37,950,846 38,211,478 RGD:737839
G Cdk5 cyclin-dependent kinase 5 JBrowse link 4 7,282,945 7,287,427 RGD:13792535
G Ehd3 EH-domain containing 3 JBrowse link 6 25,076,012 25,102,457 RGD:1600115
RGD:1624291
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:7243967
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 JBrowse link 11 32,434,786 32,447,264 RGD:7243967
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:7243967
G S100a1 S100 calcium binding protein A1 JBrowse link 2 189,900,505 189,905,348 RGD:7205633
G Stac SH3 and cysteine rich domain JBrowse link 8 119,820,664 119,941,867 RGD:1624291
RGD:13792537
G Stac2 SH3 and cysteine rich domain 2 JBrowse link 10 85,988,367 86,004,209 RGD:1624291
RGD:13792537
G Stac3 SH3 and cysteine rich domain 3 JBrowse link 7 70,807,427 70,815,271 RGD:1624291
RGD:13792537
positive regulation of voltage-gated potassium channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc8 ATP binding cassette subfamily C member 8 JBrowse link 1 102,110,708 102,191,287 RGD:728122
G Amigo1 adhesion molecule with Ig like domain 1 JBrowse link 2 210,977,125 210,982,582 RGD:14390155
G Kcna1 potassium voltage-gated channel subfamily A member 1 JBrowse link 4 159,190,781 159,192,526 RGD:7242916
G Kcnc1 potassium voltage-gated channel subfamily C member 1 JBrowse link 1 102,414,352 102,456,718 RGD:12910700
G Kcnc2 potassium voltage-gated channel subfamily C member 2 JBrowse link 7 54,978,453 55,159,362 RGD:12910700
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:12910723
G Lrrc26 leucine rich repeat containing 26 JBrowse link 3 2,506,426 2,507,752 RGD:1624291
RGD:1600115
G Lrrc38 leucine rich repeat containing 38 JBrowse link 5 162,031,722 162,053,723 RGD:1624291
RGD:1600115
G Lrrc52 leucine rich repeat containing 52 JBrowse link 13 85,672,013 85,695,421 RGD:1624291
RGD:1600115
G Lrrc55 leucine rich repeat containing 55 JBrowse link 3 72,589,840 72,605,089 RGD:1624291
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf207 ring finger protein 207 JBrowse link 5 169,486,253 169,500,451 RGD:1624291
RGD:1600115
positive regulation of voltage-gated sodium channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kif5b kinesin family member 5B JBrowse link 17 54,181,416 54,219,048 RGD:11073607

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    positive regulation of biological process 6219
      positive regulation of transport 1144
        positive regulation of transporter activity 129
          positive regulation of ion transmembrane transporter activity 122
            positive regulation of cation channel activity 85
              positive regulation of AMPA receptor activity 9
              positive regulation of NMDA glutamate receptor activity 9
              positive regulation of acid-sensing ion channel activity 0
              positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 4
              positive regulation of large conductance calcium-activated potassium channel activity 4
              positive regulation of osmolarity-sensing cation channel activity 0
              positive regulation of proton-transporting ATP synthase activity, rotational mechanism 2
              positive regulation of ryanodine-sensitive calcium-release channel activity 8
              positive regulation of store-operated calcium channel activity + 8
              positive regulation of voltage-gated calcium channel activity + 15
              positive regulation of voltage-gated potassium channel activity + 15
              positive regulation of voltage-gated sodium channel activity 1
Path 2
Term Annotations click to browse term
  biological_process 18166
    biological regulation 12793
      regulation of biological process 12128
        regulation of localization 2955
          regulation of transport 2036
            regulation of transmembrane transport 594
              regulation of ion transmembrane transport 496
                regulation of ion transmembrane transporter activity 273
                  regulation of cation channel activity 185
                    positive regulation of cation channel activity 85
                      positive regulation of AMPA receptor activity 9
                      positive regulation of NMDA glutamate receptor activity 9
                      positive regulation of acid-sensing ion channel activity 0
                      positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 4
                      positive regulation of large conductance calcium-activated potassium channel activity 4
                      positive regulation of osmolarity-sensing cation channel activity 0
                      positive regulation of proton-transporting ATP synthase activity, rotational mechanism 2
                      positive regulation of ryanodine-sensitive calcium-release channel activity 8
                      positive regulation of store-operated calcium channel activity + 8
                      positive regulation of voltage-gated calcium channel activity + 15
                      positive regulation of voltage-gated potassium channel activity + 15
                      positive regulation of voltage-gated sodium channel activity 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.