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Term:Optic atrophy
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Accession:HP:0000648 term browser browse the term
Definition:Atrophy of the optic nerve. Optic atrophy results from the death of the retinal ganglion cell axons that comprise the optic nerve and manifesting as a pale optic nerve on fundoscopy.
Comment:The diagnosis of optic atrophy is made when the optic disc loses its normal orange-pink color. Optic atrophy is an end stage that arises from myriad causes of optic nerve damage anywhere along the path from the retina to the lateral geniculate. Some of the most common etiologies are advanced glaucoma, optic neuritis, arteritic or non-arteritic ischaemic optic neuropathy or a compressive lesion.
Synonyms:exact_synonym: Optic nerve atrophy;   Optic-nerve degeneration
 alt_id: HP:0007751;   HP:0007855
 xref: MSH:D009896;   SNOMEDCT_US:76976005;   UMLS:C0029124

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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the eye 0
        Abnormal eye morphology 0
          Abnormal posterior eye segment morphology 0
            Abnormal fundus morphology 0
              Abnormality of the optic nerve 0
                Abnormality of the optic disc 0
                  Optic atrophy 0
                    Optic atrophy from cranial nerve compression 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.