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Term:Increased number of teeth
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Accession:HP:0011069 term browser browse the term
Definition:The presence of a supernumerary, i.e., extra, tooth or teeth.
Comment:The most frequent supernumerary tooth is a mesiodens, which occurs between the two maxillary central incisors. Often it fails to erupt, but creates a large anterior diastema, and would not be detected on physical examination (requires X-ray evaluation). This designation excludes coexistence of primary and permanent dentition due to delayed loss of the former. Note that this term does not refer to the situation in which two rows of teeth are seen at the time of eruption of permanent dentition before exfoliation of primary teeth, which can be a normal finding.
Synonyms:exact_synonym: Extra teeth;   Hyperdontia;   Increased tooth count;   Supernumerary teeth;   Supernumerary tooth;   Supplemental dentition;   Supplemental teeth
 narrow_synonym: Supernumary dentition;   Supernumary teeth
 related_synonym: More teeth than normal
 alt_id: HP:0000672
 xref: MSH:D014096;   SNOMEDCT_US:266414008;   SNOMEDCT_US:367534004;   SNOMEDCT_US:8666004;   UMLS:C0040457

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Increased number of teeth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 JBrowse link 4 72,280,969 72,569,221 RGD:8699517
G AMMECR1 AMMECR nuclear protein 1 JBrowse link X 110,194,186 110,440,233 RGD:8699517
G APC APC regulator of WNT signaling pathway JBrowse link 5 112,707,498 112,846,239 RGD:8699517
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 JBrowse link 8 20,197,375 20,226,852 RGD:8699517
G BCOR BCL6 corepressor JBrowse link X 40,051,246 40,177,390 RGD:8699517
G C2CD3 C2 domain containing 3 centriole elongation regulator JBrowse link 11 74,012,578 74,171,210 RGD:8699517
G CCBE1 collagen and calcium binding EGF domains 1 JBrowse link 18 59,430,939 59,698,181 RGD:8699517
G DDX59 DEAD-box helicase 59 JBrowse link 1 200,640,805 200,669,998 RGD:8699517
G DHCR7 7-dehydrocholesterol reductase JBrowse link 11 71,434,411 71,448,431 RGD:8699517
G DVL1 dishevelled segment polarity protein 1 JBrowse link 1 1,335,278 1,349,418 RGD:8699517
G DVL3 dishevelled segment polarity protein 3 JBrowse link 3 184,155,311 184,173,614 RGD:8699517
G DYNC2LI1 dynein cytoplasmic 2 light intermediate chain 1 JBrowse link 2 43,774,039 43,828,320 RGD:8699517
G EXT1 exostosin glycosyltransferase 1 JBrowse link 8 117,799,363 118,111,819 RGD:8699517
G FAT4 FAT atypical cadherin 4 JBrowse link 4 125,314,913 125,492,932 RGD:8699517
G FGF3 fibroblast growth factor 3 JBrowse link 11 69,809,968 69,819,416 RGD:8699517
G FZD2 frizzled class receptor 2 JBrowse link 17 44,557,484 44,561,262 RGD:8699517
G HSPG2 heparan sulfate proteoglycan 2 JBrowse link 1 21,822,244 21,937,310 RGD:8699517
G IL11RA interleukin 11 receptor subunit alpha JBrowse link 9 34,652,185 34,661,902 RGD:8699517
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 JBrowse link X 109,623,700 109,625,172 RGD:8699517
G KCNH1 potassium voltage-gated channel subfamily H member 1 JBrowse link 1 210,678,314 211,134,148 RGD:8699517
G MSX2 msh homeobox 2 JBrowse link 5 174,724,582 174,730,896 RGD:8699517
G NHS NHS actin remodeling regulator JBrowse link X 17,375,200 17,735,994 RGD:8699517
G NXN nucleoredoxin JBrowse link 17 799,310 979,776 RGD:8699517
G OFD1 OFD1 centriole and centriolar satellite protein JBrowse link X 13,734,713 13,773,978 RGD:8699517
G PIGL phosphatidylinositol glycan anchor biosynthesis class L JBrowse link 17 16,217,209 16,351,800 RGD:8699517
G RECQL4 RecQ like helicase 4 JBrowse link 8 144,511,284 144,517,828 RGD:8699517
G ROR2 receptor tyrosine kinase like orphan receptor 2 JBrowse link 9 91,722,598 91,950,228 RGD:8699517
G RPS23 ribosomal protein S23 JBrowse link 5 82,273,320 82,278,354 RGD:8699517
G RUNX2 RUNX family transcription factor 2 JBrowse link 6 45,328,317 45,551,082 RGD:8699517
G TRPS1 transcriptional repressor GATA binding 1 JBrowse link 8 115,408,496 115,669,637 RGD:8699517
G WNT5A Wnt family member 5A JBrowse link 3 55,465,715 55,505,261 RGD:8699517
Mesiodens term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAMTA1 calmodulin binding transcription activator 1 JBrowse link 1 6,785,324 7,769,706 RGD:8699517
G PUF60 poly(U) binding splicing factor 60 JBrowse link 8 143,816,344 143,830,041 RGD:8699517
Supernumerary maxillary incisor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IRF6 interferon regulatory factor 6 JBrowse link 1 209,785,617 209,806,175 RGD:8699517
G MSX1 msh homeobox 1 JBrowse link 4 4,859,665 4,863,936 RGD:8699517
G NECTIN1 nectin cell adhesion molecule 1 JBrowse link 11 119,638,098 119,729,200 RGD:8699517
G NHS NHS actin remodeling regulator JBrowse link X 17,375,200 17,735,994 RGD:8699517
G TP63 tumor protein p63 JBrowse link 3 189,596,746 189,897,279 RGD:8699517

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  Human phenotype 5901
    Phenotypic abnormality 5897
      Abnormality of head or neck 2581
        Abnormality of the head 2564
          Abnormality of the face 2331
            Abnormality of the mouth 1756
              Abnormal oral morphology 1641
                Abnormal oral cavity morphology 1641
                  Abnormality of the dentition 761
                    Abnormal number of teeth 276
                      Increased number of teeth 37
                        Mesiodens 2
                        Supernumerary maxillary incisor 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.