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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal cell proliferation
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Accession:MP:0000350 term browser browse the term
Definition:anomaly in the ability of a cell population to undergo expansion by cell division


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decreased fibroblast proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myc MYC proto-oncogene, bHLH transcription factor IMP RGD PMID:22842522 RGD:7207891 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
decreased T cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd247 Cd247 molecule IMP compared to wild-type RGD PMID:24343121 RGD:13442481 NCBI chr13:83,996,045...84,071,408
Ensembl chr13:83,996,080...84,071,400
JBrowse link
G Cd247em1Mcwi Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:24343121 RGD:13442481
increased cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 IDA RGD PMID:12668975 RGD:704417 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ednrb endothelin receptor type B IMP RGD PMID:18683040 RGD:4892578 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Lpin1 lipin 1 IMP RGD PMID:21715287 RGD:38599010 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
increased T cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Themis thymocyte selection associated IAGP DNA:frameshift mutation: RGD PMID:22275874 RGD:38599149 NCBI chr 1:17,152,973...17,378,225
Ensembl chr 1:17,171,631...17,378,047
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 4999
    cellular phenotype 75
      abnormal cell physiology 61
        abnormal cell proliferation 15
          abnormal B cell proliferation + 0
          abnormal CD8-positive, alpha-beta memory T cell proliferation + 0
          abnormal Schwann cell proliferation + 0
          abnormal T cell proliferation + 8
          abnormal chondrocyte proliferation + 0
          abnormal endothelial cell proliferation + 0
          abnormal enterocyte proliferation 0
          abnormal epidermal stem cell proliferation 0
          abnormal fetal cardiomyocyte proliferation + 0
          abnormal fibroblast proliferation + 1
          abnormal granulosa cell proliferation + 0
          abnormal hematopoietic stem cell proliferation + 0
          abnormal inner cell mass proliferation + 0
          abnormal keratinocyte proliferation + 0
          abnormal kidney cell proliferation + 0
          abnormal lung endothelial cell proliferation + 0
          abnormal macrophage proliferation + 0
          abnormal melanoblast proliferation + 0
          abnormal melanocyte proliferation 0
          abnormal mesenchymal cell proliferation involved in lung development + 0
          abnormal myoblast proliferation + 0
          abnormal neural crest cell proliferation + 0
          abnormal neuron proliferation + 0
          abnormal organ of Corti supporting cell proliferation 0
          abnormal osteoblast proliferation + 0
          abnormal pancreatic beta cell proliferation + 1
          abnormal pancreatic endocrine progenitor cell proliferation + 0
          abnormal primordial germ cell proliferation + 0
          abnormal skeletal muscle satellite cell proliferation 0
          abnormal small intestinal crypt cell proliferation 0
          abnormal spermatogonia proliferation 0
          abnormal splenocyte proliferation + 0
          abnormal trophectoderm cell proliferation + 0
          abnormal trophoblast giant cell proliferation 0
          abnormal vascular endothelial cell proliferation + 0
          decreased cell proliferation + 4
          increased cell proliferation + 10
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.