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ONTOLOGY REPORT - ANNOTATIONS


Term:abnormal adaptive immunity
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Accession:MP:0002420 term browser browse the term
Definition:anomaly in the function of the response of antigen-specific lymphocytes to antigen, including the development of immunological memory
Synonyms:exact_synonym: acquired immune response dysfunction;   adaptive immunity dysfunction


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abnormal microglial cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:12879399
G Atmem1Kyo ATM serine/threonine kinase; ZFN induced mutant 1, Kyo RGD:12879399
decreased immunoglobulin level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:8696027
increased susceptibility to type III hypersensitivity reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:13792592
G Cd59em1Ask CD59 molecule; CRISPR/Cas9 induced mutant1, Ask RGD:13792592

Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 4930
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal adaptive immunity 35
          abnormal leukocyte physiology + 32
          abnormal professional antigen presenting cell physiology + 26
          abnormal somatic hypermutation frequency 0
          abnormal type I hypersensitivity reaction + 0
          abnormal type II hypersensitivity reaction + 1
          abnormal type III hypersensitivity reaction + 3
          abnormal type IV hypersensitivity reaction + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.