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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal T cell physiology
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Accession:MP:0002444 term browser browse the term
Definition:any functional anomaly of lymphocytes that are responsible for cell-mediated immunity and immune system regulation
Synonyms:exact_synonym: abnormal T cell function;   abnormal T lymphocyte function
 narrow_synonym: T-cell dysfunction;   t lymphocyte dysfunction


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decreased T cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd247 Cd247 molecule IMP compared to wild-type RGD PMID:24343121 RGD:13442481 NCBI chr13:83,996,045...84,071,408
Ensembl chr13:83,996,080...84,071,400
JBrowse link
G Cd247em1Mcwi Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:24343121 RGD:13442481

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  mammalian phenotype 4967
    immune system phenotype 427
      abnormal immune system physiology 346
        abnormal immune cell physiology 36
          abnormal leukocyte physiology 36
            abnormal lymphocyte physiology 33
              abnormal T cell physiology 6
                abnormal CD4-positive, alpha-beta T cell physiology + 0
                abnormal CD8-positive, alpha-beta T cell physiology + 0
                abnormal NK T cell physiology 0
                abnormal T cell activation + 6
                abnormal T cell apoptosis + 0
                abnormal memory T cell physiology + 0
                abnormal regulatory T cell physiology + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.