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ONTOLOGY REPORT - ANNOTATIONS


Term:abnormal macrophage physiology
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Accession:MP:0002451 term browser browse the term
Definition:any functional anomaly of the large mononuclear phagocytes which differentiate from monocytes, are typically resident in a particular tissue, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells
Synonyms:exact_synonym: macrophage dysfunction


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abnormal microglial cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:12879399
G Atmem1Kyo ATM serine/threonine kinase; ZFN induced mutant 1, Kyo RGD:12879399

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 4930
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal innate immunity 15
          abnormal macrophage physiology 3
            abnormal macrophage activation involved in immune response 0
            abnormal macrophage antigen presentation + 0
            abnormal macrophage apoptosis + 0
            abnormal macrophage chemotaxis + 0
            abnormal macrophage cytokine production + 0
            abnormal macrophage nitric oxide production + 0
            abnormal macrophage proliferation + 0
            abnormal microglial cell physiology + 3
            abnormal osteoclast physiology 0
            impaired macrophage phagocytosis 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 4930
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal cell-mediated immunity 32
          abnormal leukocyte physiology 32
            abnormal macrophage physiology 3
              abnormal macrophage activation involved in immune response 0
              abnormal macrophage antigen presentation + 0
              abnormal macrophage apoptosis + 0
              abnormal macrophage chemotaxis + 0
              abnormal macrophage cytokine production + 0
              abnormal macrophage nitric oxide production + 0
              abnormal macrophage proliferation + 0
              abnormal microglial cell physiology + 3
              abnormal osteoclast physiology 0
              impaired macrophage phagocytosis 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.