Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:abnormal type I hypersensitivity reaction
go back to main search page
Accession:MP:0002531 term browser browse the term
Definition:anomaly in a reaction manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks
Comment:Examples: hay fever, asthma, and anaphylaxis.
Synonyms:exact_synonym: anaphylactic shock;   anaphylaxis;   immediate type hypersensitivity


show annotations for term's descendants       view all columns           Sort by:
 
abnormal type I hypersensitivity reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide JBrowse link 1 173,221,269 173,227,232 RGD:5509061
G Fcgr1 Fc receptor, IgG, high affinity I JBrowse link 3 96,282,909 96,293,969 RGD:5509061
G Fcgr3 Fc receptor, IgG, low affinity III JBrowse link 1 171,051,169 171,065,915 RGD:5509061
G Il13 interleukin 13 JBrowse link 11 53,631,323 53,634,702 RGD:5509061
G Ltc4s leukotriene C4 synthase JBrowse link 11 50,236,461 50,238,532 RGD:5509061
G Tbxa2r thromboxane A2 receptor JBrowse link 10 81,328,268 81,335,174 RGD:5509061
G Vamp8 vesicle-associated membrane protein 8 JBrowse link 6 72,385,221 72,390,667 RGD:5509061
decreased susceptibility to type I hypersensitivity reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 6 116,410,071 116,461,178 RGD:5509061
G Alox5ap arachidonate 5-lipoxygenase activating protein JBrowse link 5 149,265,004 149,288,153 RGD:5509061
G Ccr2 chemokine (C-C motif) receptor 2 JBrowse link 9 124,101,918 124,109,140 RGD:5509061
G Ccr6 chemokine (C-C motif) receptor 6 JBrowse link 17 8,236,041 8,258,519 RGD:5509061
G Ccrl2 chemokine (C-C motif) receptor-like 2 JBrowse link 9 111,054,834 111,057,518 RGD:5509061
G Cd81 CD81 antigen JBrowse link 7 143,052,750 143,067,930 RGD:5509061
G Cpa3 carboxypeptidase A3, mast cell JBrowse link 3 20,215,616 20,242,209 RGD:5509061
G Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) JBrowse link 15 78,325,800 78,351,001 RGD:5509061
G Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) JBrowse link 15 78,282,507 78,305,721 RGD:5509061
G Cysltr1 cysteinyl leukotriene receptor 1 JBrowse link X 106,576,509 106,603,679 RGD:5509061
G Cysltr2 cysteinyl leukotriene receptor 2 JBrowse link 14 73,025,672 73,049,114 RGD:5509061
G Ecm1 extracellular matrix protein 1 JBrowse link 3 95,734,147 95,739,876 RGD:5509061
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide JBrowse link 1 173,221,269 173,227,232 RGD:5509061
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide JBrowse link 1 171,229,572 171,234,349 RGD:5509061
G Fcgr3 Fc receptor, IgG, low affinity III JBrowse link 1 171,051,169 171,065,915 RGD:5509061
G Gab2 growth factor receptor bound protein 2-associated protein 2 JBrowse link 7 97,081,751 97,308,951 RGD:5509061
G Gna11 guanine nucleotide binding protein, alpha 11 JBrowse link 10 81,528,724 81,545,162 RGD:5509061
G Gnaq guanine nucleotide binding protein, alpha q polypeptide JBrowse link 19 16,132,684 16,388,520 RGD:5509061
G Igf1r insulin-like growth factor I receptor JBrowse link 7 67,952,257 68,233,668 RGD:5509061
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 5 75,574,987 75,656,722 RGD:5509061
G Lbp lipopolysaccharide binding protein JBrowse link 2 158,306,493 158,332,852 RGD:5509061
G Lta4h leukotriene A4 hydrolase JBrowse link 10 93,453,396 93,484,896 RGD:5509061
G Ltb4r1 leukotriene B4 receptor 1 JBrowse link 14 55,765,962 55,768,492 RGD:5509061
G Ltb4r2 leukotriene B4 receptor 2 JBrowse link 14 55,757,922 55,764,066 RGD:5509061
G Ltc4s leukotriene C4 synthase JBrowse link 11 50,236,461 50,238,532 RGD:5509061
G Mcl1 myeloid cell leukemia sequence 1 JBrowse link 3 95,656,944 95,663,179 RGD:5509061
G Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 JBrowse link 19 11,615,517 11,623,790 RGD:5509061
G Ndor1 NADPH dependent diflavin oxidoreductase 1 JBrowse link 2 25,244,813 25,255,509 RGD:5509061
G Orai1 ORAI calcium release-activated calcium modulator 1 JBrowse link 5 123,015,074 123,030,452 RGD:5509061
G Pla2g3 phospholipase A2, group III JBrowse link 11 3,488,158 3,499,346 RGD:5509061
G Ptgdr prostaglandin D receptor JBrowse link 14 44,851,235 44,859,375 RGD:5509061
G Ptgds prostaglandin D2 synthase (brain) JBrowse link 2 25,466,709 25,470,110 RGD:5509061
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 1 138,062,859 138,175,756 RGD:5509061
G Rhoh ras homolog family member H JBrowse link 5 65,860,742 65,896,700 RGD:5509061
G Serpinb3a serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A JBrowse link 1 107,045,587 107,052,303 RGD:5509061
G Stim1 stromal interaction molecule 1 JBrowse link 7 102,261,514 102,437,319 RGD:5509061
G Stxbp2 syntaxin binding protein 2 JBrowse link 8 3,630,960 3,643,998 RGD:5509061
G Suv39h1 suppressor of variegation 3-9 1 JBrowse link X 8,061,171 8,074,760 RGD:5509061
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 17 56,269,462 56,276,767 RGD:5509061
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 JBrowse link 4 156,013,595 156,016,613 RGD:5509061
G Vipr2 vasoactive intestinal peptide receptor 2 JBrowse link 12 116,077,420 116,148,637 RGD:5509061
increased susceptibility to type I hypersensitivity reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2b adenosine A2b receptor JBrowse link 11 62,248,984 62,266,452 RGD:5509061
G C3ar1 complement component 3a receptor 1 JBrowse link 6 122,847,140 122,856,157 RGD:5509061
G Cd276 CD276 antigen JBrowse link 9 58,524,300 58,555,033 RGD:5509061
G Cd28 CD28 antigen JBrowse link 1 60,746,388 60,773,359 RGD:5509061
G Cd300lf CD300 molecule like family member F JBrowse link 11 115,116,214 115,135,372 RGD:5509061
G Cish cytokine inducible SH2-containing protein JBrowse link 9 107,296,659 107,302,784 RGD:5509061
G Coro1a coronin, actin binding protein 1A JBrowse link 7 126,699,774 126,704,816 RGD:5509061
G Coro1b coronin, actin binding protein 1B JBrowse link 19 4,148,611 4,154,035 RGD:5509061
G Dusp1 dual specificity phosphatase 1 JBrowse link 17 26,505,591 26,508,472 RGD:5509061
G Dusp10 dual specificity phosphatase 10 JBrowse link 1 184,034,381 184,075,636 RGD:5509061
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 JBrowse link 10 24,773,814 24,836,195 RGD:5509061
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide JBrowse link 1 173,221,269 173,227,232 RGD:5509061
G Fcer2a Fc receptor, IgE, low affinity II, alpha polypeptide JBrowse link 8 3,680,280 3,694,174 RGD:5509061
G Fcgr1 Fc receptor, IgG, high affinity I JBrowse link 3 96,282,909 96,293,969 RGD:5509061
G Fcgr2b Fc receptor, IgG, low affinity IIb JBrowse link 1 170,960,558 170,976,071 RGD:5509061
G Fcgr3 Fc receptor, IgG, low affinity III JBrowse link 1 171,051,169 171,065,915 RGD:5509061
G Fyn Fyn proto-oncogene JBrowse link 10 39,369,743 39,565,381 RGD:5509061
G Hpgds hematopoietic prostaglandin D synthase JBrowse link 6 65,117,293 65,144,981 RGD:5509061
G Ighg1 immunoglobulin heavy constant gamma 1 (G1m marker) JBrowse link 12 113,326,541 113,330,523 RGD:5509061
G Il13 interleukin 13 JBrowse link 11 53,631,323 53,634,702 RGD:5509061
G Il25 interleukin 25 JBrowse link 14 54,932,695 54,935,837 RGD:5509061
G Il4ra interleukin 4 receptor, alpha JBrowse link 7 125,552,271 125,579,474 RGD:5509061
G Lilrb4a leukocyte immunoglobulin-like receptor, subfamily B, member 4A JBrowse link 10 51,490,898 51,496,613 RGD:5509061
G Lpar2 lysophosphatidic acid receptor 2 JBrowse link 8 69,822,565 69,831,102 RGD:5509061
G Lyz2 lysozyme 2 JBrowse link 10 117,277,541 117,282,272 RGD:5509061
G Mfsd2b major facilitator superfamily domain containing 2B JBrowse link 12 4,862,438 4,874,359 RGD:5509061
G Milr1 mast cell immunoglobulin like receptor 1 JBrowse link 11 106,750,646 106,768,794 RGD:5509061
G Mir21a microRNA 21a JBrowse link 11 86,584,067 86,584,158 RGD:5509061
G Mme membrane metallo endopeptidase JBrowse link 3 63,295,211 63,383,713 RGD:5509061
G Orai2 ORAI calcium release-activated calcium modulator 2 JBrowse link 5 136,147,456 136,170,697 RGD:5509061
G Pikfyve phosphoinositide kinase, FYVE type zinc finger containing JBrowse link 1 65,186,640 65,278,696 RGD:5509061
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase, type 1 beta JBrowse link 19 24,294,794 24,555,872 RGD:5509061
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) JBrowse link 1 149,829,618 149,961,290 RGD:5509061
G Ppia peptidylprolyl isomerase A JBrowse link 11 6,415,867 6,419,817 RGD:5509061
G Ptafr platelet-activating factor receptor JBrowse link 4 132,564,067 132,582,683 RGD:5509061
G Ptgdr2 prostaglandin D2 receptor 2 JBrowse link 19 10,924,519 10,942,511 RGD:5509061
G Ptger3 prostaglandin E receptor 3 (subtype EP3) JBrowse link 3 157,566,821 157,644,758 RGD:5509061
G Ptges prostaglandin E synthase JBrowse link 2 30,889,471 30,931,020 RGD:5509061
G Ptges2 prostaglandin E synthase 2 JBrowse link 2 32,395,890 32,402,740 RGD:5509061
G Rgs13 regulator of G-protein signaling 13 JBrowse link 1 144,137,386 144,177,372 RGD:5509061
G Rgs3 regulator of G-protein signaling 3 JBrowse link 4 62,559,835 62,703,019 RGD:5509061
G Stard7 START domain containing 7 JBrowse link 2 127,270,202 127,298,935 RGD:5509061
G Tbxa2r thromboxane A2 receptor JBrowse link 10 81,328,268 81,335,174 RGD:5509061
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a JBrowse link 6 125,349,723 125,362,483 RGD:5509061
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 7 45,303,155 45,334,071 RGD:5509061

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 14671
    immune system phenotype 4495
      abnormal immune system physiology 3123
        abnormal hypersensitivity reaction 193
          abnormal type I hypersensitivity reaction 86
            decreased susceptibility to type I hypersensitivity reaction 41
            increased susceptibility to type I hypersensitivity reaction 45
Path 2
Term Annotations click to browse term
  mammalian phenotype 14671
    immune system phenotype 4495
      abnormal immune system physiology 3123
        abnormal inflammatory response 1618
          abnormal acute inflammation 377
            abnormal type I hypersensitivity reaction 86
              decreased susceptibility to type I hypersensitivity reaction 41
              increased susceptibility to type I hypersensitivity reaction 45
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.