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ONTOLOGY REPORT - ANNOTATIONS


Term:abnormal type II hypersensitivity reaction
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Accession:MP:0002532 term browser browse the term
Definition:anomaly in the response caused by an Ag-Ab reaction; antibodies are directly or indirectly cytotoxic to antigens on cell surfaces or in connective tissues; most often involves IgG and IgM; complement activation is usually involved
Comment:Examples: autoimmune diseases: autoimmune hemolytic anemias, antibody-dependent cellular cytotoxicity (ADCC), Goodpasture disease, myasthenia gravis, Graves disease, pemphigous, and pemphigoid.
Synonyms:exact_synonym: antibody-mediated cellular toxicity;   cytotoxic type hypersensitivity


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increased susceptibility to type II hypersensitivity reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
Q Iresp1 Immunoglobin response QTL1 JBrowse link 20 9,655,642 14,411,641 RGD:619646

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Term Annotations click to browse term
  mammalian phenotype 4926
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal hypersensitivity reaction 4
          abnormal type II hypersensitivity reaction 1
            decreased susceptibility to type II hypersensitivity reaction 0
            increased susceptibility to type II hypersensitivity reaction 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 4926
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal inflammatory response 227
          abnormal acute inflammation 5
            abnormal type II hypersensitivity reaction 1
              decreased susceptibility to type II hypersensitivity reaction 0
              increased susceptibility to type II hypersensitivity reaction 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.