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ONTOLOGY REPORT - ANNOTATIONS


Term:abnormal type III hypersensitivity reaction
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Accession:MP:0002533 term browser browse the term
Definition:anomaly in the tissue injury mediated by immune complexes; generally involves immune complexes formed in the blood via Abs encountering circulating Ag-Ab complexes then deposit in tissues (especially blood vessels and glomeruli), induce complement activation, and result in tissue injury
Comment:Examples: Autoimmune diseases: systemic lupus erythmatosus (SLE), rheumatoid arthritis, sjogren syndrome, scleroderma and glomerulonephritis.
Synonyms:exact_synonym: immune complex mediated hypersensitivity


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increased susceptibility to type III hypersensitivity reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:13792592
G Cd59em1Ask CD59 molecule; CRISPR/Cas9 induced mutant1, Ask RGD:13792592

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Term Annotations click to browse term
  mammalian phenotype 4928
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal hypersensitivity reaction 4
          abnormal type III hypersensitivity reaction 3
            decreased susceptibility to type III hypersensitivity reaction 0
            increased susceptibility to type III hypersensitivity reaction 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 4928
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal inflammatory response 228
          abnormal acute inflammation 5
            abnormal type III hypersensitivity reaction 3
              decreased susceptibility to type III hypersensitivity reaction 0
              increased susceptibility to type III hypersensitivity reaction 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.