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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal Leydig cell morphology
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Accession:MP:0002786 term browser browse the term
Definition:any structural anomaly of the interstitial cells that are found adjacent to the seminiferous tubules in the testicle and produce testosterone in the presence of luteinizing hormone (LH); Leydig cells are polyhedral in shape, display a large prominent nucleus, an eosinophilic cytoplasm and numerous lipid-filled vesicles
Synonyms:exact_synonym: abnormal Leydig cells


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abnormal adult Leydig cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhh desert hedgehog signaling molecule IMP RGD PMID:21062903 RGD:38548923 NCBI chr 7:140,575,288...140,580,783
Ensembl chr 7:140,575,288...140,580,783
JBrowse link
abnormal fetal Leydig cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhh desert hedgehog signaling molecule IMP RGD PMID:21062903 RGD:38548923 NCBI chr 7:140,575,288...140,580,783
Ensembl chr 7:140,575,288...140,580,783
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 4967
    reproductive system phenotype 82
      abnormal reproductive system morphology 60
        abnormal sex gland morphology 41
          abnormal male reproductive gland morphology 37
            abnormal testis morphology 29
              abnormal seminiferous tubule morphology 8
                abnormal Leydig cell morphology 2
                  Leydig cell atrophy 0
                  Leydig cell hyperplasia 0
                  Leydig cell hypertrophy 0
                  Leydig cell hypoplasia 0
                  abnormal Leydig cell differentiation + 2
                  absent Leydig cells 0
                  ectopic Leydig cells 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 4967
    reproductive system phenotype 82
      abnormal reproductive system morphology 60
        abnormal male reproductive system morphology 39
          abnormal male genitalia morphology 39
            abnormal internal male genitalia morphology 34
              abnormal testis morphology 29
                abnormal seminiferous tubule morphology 8
                  abnormal Leydig cell morphology 2
                    Leydig cell atrophy 0
                    Leydig cell hyperplasia 0
                    Leydig cell hypertrophy 0
                    Leydig cell hypoplasia 0
                    abnormal Leydig cell differentiation + 2
                    absent Leydig cells 0
                    ectopic Leydig cells 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.