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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased osteosarcoma incidence
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Accession:MP:0003789 term browser browse the term
Definition:greater than the expected number of a malignant neoplasm derived form mesenchymal stem cells, osteoblasts or osteocytes, occurring in a specific population in a given time period; osteosarcoma is a highly invasive and destructive tumor rising in the skeleton with osteoid and immature woven bone
Synonyms:related_synonym: osteogenic sarcoma


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increased osteosarcoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 IAGP DNA:deletion RGD PMID:19825367 RGD:5147850 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
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Path 1
Term Annotations click to browse term
  mammalian phenotype 4987
    skeleton phenotype 379
      abnormal skeleton morphology 292
        increased skeletal tumor incidence 1
          increased osteosarcoma incidence 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 4987
    neoplasm 229
      altered tumor susceptibility 222
        abnormal tumor incidence 211
          increased tumor incidence 154
            increased classified tumor incidence 101
              increased malignant tumor incidence 60
                increased sarcoma incidence 2
                  increased osteosarcoma incidence 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.