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ONTOLOGY REPORT - ANNOTATIONS


Term:abnormal basement membrane morphology
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Accession:MP:0004272 term browser browse the term
Definition:anomaly in the structure, organization and/or placement of the extracellular supportive tissue adjacent to the basal surface of the epithelia, including the epithelium of muscle cells, fat cells and Schwann cells; it is comprised of type IV collagen, laminin, and sulfated proteoglycans and other components and consists of two layers, the basal lamina and the lamina reticularis
Comment:Note: Basal lamina and lamina reticularis (or of two basal laminae) compose the basement membrane. Thus, in strict sense, the term basement membrane is different from and should not be confused with basal lamina.
Synonyms:exact_synonym: abnormal basement lamina morphology;   basement membrane dysplasia


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impaired basement membrane formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
Q Edpm11 Estrogen-dependent pituitary mass QTL 11 JBrowse link 9 2,355,722 47,355,722 RGD:629550

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  mammalian phenotype 5083
    cellular phenotype 59
      abnormal extracellular matrix morphology 1
        abnormal basement membrane morphology 1
          abnormal basal lamina morphology 0
          abnormal cochlear basement membrane morphology 0
          impaired basement membrane formation 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.