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ONTOLOGY REPORT - ANNOTATIONS


Term:abnormal somatic hypermutation frequency
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Accession:MP:0004815 term browser browse the term
Definition:any anomaly in the high frequency of programmed mutation that occurs in the gene segments encoding the variable regions of antibodies during the differentiation of individual B lymphocytes into antibody producing plasma cells
Synonyms:exact_synonym: abnormal SHM


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  mammalian phenotype 4926
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal adaptive immunity 35
          abnormal somatic hypermutation frequency 0
Path 2
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  mammalian phenotype 4926
    hematopoietic system phenotype 164
      abnormal hematopoietic system morphology/development 148
        abnormal hematopoietic cell morphology 123
          abnormal blood cell morphology 59
            abnormal hemopoiesis 9
              abnormal definitive hematopoiesis 9
                abnormal leukopoiesis 9
                  abnormal lymphopoiesis 9
                    abnormal B cell differentiation 0
                      abnormal somatic hypermutation frequency 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.