Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:increased susceptibility to type I hypersensitivity reaction
go back to main search page
Accession:MP:0005596 term browser browse the term
Definition:greater likelihood of developing a response manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks
Comment:Examples of this type of hypersensitivity include hay fever, asthma, and anaphylaxis.
Synonyms:exact_synonym: decreased resistance to anaphylactic shock;   decreased resistance to anaphylaxis;   decreased resistance to immediate type hypersensitivity;   decreased resistance to type I hypersensitivity reaction;   increased susceptibility to allergic response;   increased susceptibility to anaphylactic shock;   increased susceptibility to anaphylaxis;   increased susceptibility to immediate type hypersensitivity
 alt_id: MP:0001878


show annotations for term's descendants       view all columns           Sort by:
 

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 4926
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal adaptive immunity 35
          abnormal type I hypersensitivity reaction 0
            increased susceptibility to type I hypersensitivity reaction 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 4926
    immune system phenotype 414
      abnormal immune system physiology 339
        abnormal inflammatory response 227
          abnormal acute inflammation 5
            abnormal type I hypersensitivity reaction 0
              increased susceptibility to type I hypersensitivity reaction 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.